Detalhe da pesquisa
1.
Strategies to lower the Pgp efflux liability in a series of potent indole azetidine MCHR1 antagonists.
Bioorg Med Chem Lett
; 21(18): 5310-4, 2011 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21802292
2.
Synthesis and SAR investigations for novel melanin-concentrating hormone 1 receptor (MCH1) antagonists Part 1. The discovery of arylacetamides as viable replacements for the dihydropyrimidinone moiety of an HTS hit.
J Med Chem
; 50(16): 3870-82, 2007 Aug 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-17668921
3.
Synthesis and SAR investigations for novel melanin-concentrating hormone 1 receptor (MCH1) antagonists part 2: A hybrid strategy combining key fragments of HTS hits.
J Med Chem
; 50(16): 3883-90, 2007 Aug 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-17668922