Detalhe da pesquisa
1.
Tumor necrosis factor receptor signaling is a driver of chronic lymphocytic leukemia that can be therapeutically targeted by the flavonoid wogonin.
Haematologica
; 103(4): 688-697, 2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29326123
2.
HTLV-1-associated adult T cell leukemia is highly susceptible to Navitoclax due to enhanced Bax expression.
Int J Cancer
; 138(2): 507-14, 2016 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26260669
3.
Molecular mechanisms and anti-cancer aspects of the medicinal phytochemicals rocaglamides (=flavaglines).
Int J Cancer
; 137(8): 1791-9, 2015 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24895251
4.
Mangrove dolabrane-type of diterpenes tagalsins suppresses tumor growth via ROS-mediated apoptosis and ATM/ATR-Chk1/Chk2-regulated cell cycle arrest.
Int J Cancer
; 137(11): 2739-48, 2015 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26061604
5.
Targeting CDK9 by wogonin and related natural flavones potentiates the anti-cancer efficacy of the Bcl-2 family inhibitor ABT-263.
Int J Cancer
; 136(3): 688-98, 2015 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24895203
6.
Regulation of IL4 gene expression by T cells and therapeutic perspectives.
Nat Rev Immunol
; 3(7): 534-43, 2003 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-12876556
7.
The Wilms' tumor suppressor WT1 enhances CD95L expression and promotes activation-induced cell death in leukemic T cells.
Int J Cancer
; 134(2): 291-300, 2014 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23832418
8.
The natural anticancer compound rocaglamide selectively inhibits the G1-S-phase transition in cancer cells through the ATM/ATR-mediated Chk1/2 cell cycle checkpoints.
Int J Cancer
; 134(8): 1991-2002, 2014 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24150948
9.
Wogonin and related natural flavones overcome tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) protein resistance of tumors by down-regulation of c-FLIP protein and up-regulation of TRAIL receptor 2 expression.
J Biol Chem
; 287(1): 641-649, 2012 Jan 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-22086925
10.
Curcumin suppresses T cell activation by blocking Ca2+ mobilization and nuclear factor of activated T cells (NFAT) activation.
J Biol Chem
; 287(13): 10200-10209, 2012 Mar 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-22303019
11.
Targeting the IL-4/IL-13 signaling pathway sensitizes Hodgkin lymphoma cells to chemotherapeutic drugs.
Int J Cancer
; 133(8): 1945-54, 2013 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23553437
12.
Rocaglamide and a XIAP inhibitor cooperatively sensitize TRAIL-mediated apoptosis in Hodgkin's lymphomas.
Int J Cancer
; 131(4): 1003-8, 2012 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21952919
13.
Early growth response protein-1 (Egr-1) is preferentially expressed in T helper type 2 (Th2) cells and is involved in acute transcription of the Th2 cytokine interleukin-4.
J Biol Chem
; 285(3): 1643-52, 2010 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19915002
14.
Treatment resistance analysis reveals GLUT-1-mediated glucose uptake as a major target of synthetic rocaglates in cancer cells.
Cancer Med
; 10(19): 6807-6822, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34546000
15.
Vitamin E inhibits CD95 ligand expression and protects T cells from activation-induced cell death.
J Clin Invest
; 110(5): 681-90, 2002 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-12208869
16.
Rocaglamide breaks TRAIL-resistance in human multiple myeloma and acute T-cell leukemia in vivo in a mouse xenogtraft model.
Cancer Lett
; 389: 70-77, 2017 03 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-27998762
17.
The anticancer phytochemical rocaglamide inhibits Rho GTPase activity and cancer cell migration.
Oncotarget
; 7(32): 51908-51921, 2016 Aug 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27340868
18.
Dolabrane-type diterpenes from the mangrove plant Ceriops tagal with antitumor activities.
Fitoterapia
; 103: 277-82, 2015 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-25936771
19.
Targeting apoptosis pathways in cancer by Chinese medicine.
Cancer Lett
; 332(2): 304-12, 2013 May 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-20685036
20.
The natural anticancer compounds rocaglamides inhibit the Raf-MEK-ERK pathway by targeting prohibitin 1 and 2.
Chem Biol
; 19(9): 1093-104, 2012 Sep 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-22999878