Detalhe da pesquisa
1.
Phosphoinositide 3-Kinase Regulates Glycolysis through Mobilization of Aldolase from the Actin Cytoskeleton.
Cell
; 164(3): 433-46, 2016 Jan 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-26824656
2.
Putting the K+ in K+aloric Restriction.
Immunity
; 50(5): 1129-1131, 2019 05 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-31117009
3.
PI3K drives the de novo synthesis of coenzyme A from vitamin B5.
Nature
; 608(7921): 192-198, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35896750
4.
Low glycaemic diets alter lipid metabolism to influence tumour growth.
Nature
; 599(7884): 302-307, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34671163
5.
Ketogenic HMG-CoA lyase and its product ß-hydroxybutyrate promote pancreatic cancer progression.
EMBO J
; 41(9): e110466, 2022 05 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-35307861
6.
Altered exocrine function can drive adipose wasting in early pancreatic cancer.
Nature
; 558(7711): 600-604, 2018 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29925948
7.
Inhibition of Rb Phosphorylation Leads to mTORC2-Mediated Activation of Akt.
Mol Cell
; 62(6): 929-942, 2016 06 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-27237051
8.
REV1 inhibitor JH-RE-06 enhances tumor cell response to chemotherapy by triggering senescence hallmarks.
Proc Natl Acad Sci U S A
; 117(46): 28918-28921, 2020 11 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-33168727
9.
Yap regulates glucose utilization and sustains nucleotide synthesis to enable organ growth.
EMBO J
; 37(22)2018 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30348863
10.
Phosphoinositide 3-kinase inhibitors induce DNA damage through nucleoside depletion.
Proc Natl Acad Sci U S A
; 113(30): E4338-47, 2016 07 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-27402769
11.
Selenoprotein H is an essential regulator of redox homeostasis that cooperates with p53 in development and tumorigenesis.
Proc Natl Acad Sci U S A
; 113(38): E5562-71, 2016 09 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-27588899
12.
Metabolic Reprogramming by the PI3K-Akt-mTOR Pathway in Cancer.
Recent Results Cancer Res
; 207: 39-72, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27557534
13.
A CRISPRi/a screening platform to study cellular nutrient transport in diverse microenvironments.
Nat Cell Biol
; 26(5): 825-838, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38605144
14.
NF1 deficiency drives metabolic reprogramming in ER+ breast cancer.
Mol Metab
; 80: 101876, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-38216123
15.
Lipid availability influences ferroptosis sensitivity in cancer cells by regulating polyunsaturated fatty acid trafficking.
bioRxiv
; 2024 May 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-38766165
16.
Proper protein glycosylation promotes mitogen-activated protein kinase signal fidelity.
Biochemistry
; 52(1): 115-24, 2013 Jan 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-23210626
17.
Tumor lipid metabolism: a mechanistic link between diet and cancer progression.
Curr Opin Biotechnol
; 84: 102993, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37716318
18.
Effects of aging on glucose and lipid metabolism in mice.
bioRxiv
; 2023 Dec 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-38187759
19.
Upregulation of Receptor Tyrosine Kinase Activity and Stemness as Resistance Mechanisms to Akt Inhibitors in Breast Cancer.
Cancers (Basel)
; 14(20)2022 Oct 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-36291790
20.
Cancer cells depend on environmental lipids for proliferation when electron acceptors are limited.
Nat Metab
; 4(6): 711-723, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35739397