Detalhe da pesquisa
1.
Structural and functional characterization of AfsR, an SARP family transcriptional activator of antibiotic biosynthesis in Streptomyces.
PLoS Biol
; 22(3): e3002528, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38427710
2.
MATT-DDI: Predicting multi-type drug-drug interactions via heterogeneous attention mechanisms.
Methods
; 220: 1-10, 2023 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37858611
3.
Structural basis of Streptomyces transcription activation by zinc uptake regulator.
Nucleic Acids Res
; 50(14): 8363-8376, 2022 08 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35871291
4.
Identification and characterization of a strong constitutive promoter stnYp for activating biosynthetic genes and producing natural products in streptomyces.
Microb Cell Fact
; 22(1): 127, 2023 Jul 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-37443029
5.
Characterization of Pyridomycin B Reveals the Formation of Functional Groups in Antimycobacterial Pyridomycin.
Appl Environ Microbiol
; 88(6): e0203521, 2022 03 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-35108072
6.
Characterization of Lysozyme-Like Effector TseP Reveals the Dependence of Type VI Secretion System (T6SS) Secretion on Effectors in Aeromonas dhakensis Strain SSU.
Appl Environ Microbiol
; 87(12): e0043521, 2021 05 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-33837015
7.
Oxidative Indole Dearomatization for Asymmetric Furoindoline Synthesis by a Flavin-Dependent Monooxygenase Involved in the Biosynthesis of Bicyclic Thiopeptide Thiostrepton.
Angew Chem Int Ed Engl
; 60(15): 8401-8405, 2021 04 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33496012
8.
RedH and PigC Catalyze the Biosynthesis of Hybrubins via Phosphorylation of 4'-Methoxy-2,2'-Bipyrrole-5'-Carbaldehyde.
Appl Environ Microbiol
; 86(2)2020 01 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31704680
9.
Characterization of an 17ß-estradiol-degrading bacterium Stenotrophomonas maltophilia SJTL3 tolerant to adverse environmental factors.
Appl Microbiol Biotechnol
; 104(3): 1291-1305, 2020 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-31834439
10.
Biosynthesis of the pyrrolidine protein synthesis inhibitor anisomycin involves novel gene ensemble and cryptic biosynthetic steps.
Proc Natl Acad Sci U S A
; 114(16): 4135-4140, 2017 04 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-28373542
11.
Functional Genome Mining Reveals a Class V Lanthipeptide Containing a d-Amino Acid Introduced by an F420 H2 -Dependent Reductase.
Angew Chem Int Ed Engl
; 59(41): 18029-18035, 2020 10 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32648341
12.
The molecular basis for the intramolecular migration (NIH shift) of the carboxyl group during para-hydroxybenzoate catabolism.
Mol Microbiol
; 110(3): 411-424, 2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30070064
13.
Structural basis of the mechanism of ß-methyl epimerization by enzyme MarH.
Org Biomol Chem
; 17(44): 9605-9614, 2019 11 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-31681917
14.
Substrate-bound structures of a ketoreductase from amphotericin modular polyketide synthase.
J Struct Biol
; 203(2): 135-141, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29626512
15.
Conserved residues Arg188 and Asp302 are critical for active site organization and catalysis in human ABO(H) blood group A and B glycosyltransferases.
Glycobiology
; 28(8): 624-636, 2018 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29873711
16.
Design and Biosynthesis of Dimeric Alboflavusins with Biaryl Linkages via Regiospecific C-C Bond Coupling.
J Am Chem Soc
; 140(51): 18009-18015, 2018 12 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-30516971
17.
Biosynthesis of Tropolones in Streptomyces spp.: Interweaving Biosynthesis and Degradation of Phenylacetic Acid and Hydroxylations on the Tropone Ring.
Appl Environ Microbiol
; 84(12)2018 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29654178
18.
StnK2 catalysing a Pictet-Spengler reaction involved in the biosynthesis of the antitumor reagent streptonigrin.
Org Biomol Chem
; 16(47): 9124-9128, 2018 12 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30483694
19.
Divergent biosynthesis of indole alkaloids FR900452 and spiro-maremycins.
Org Biomol Chem
; 16(30): 5446-5451, 2018 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30020298
20.
Synthesis, antimycobacterial activity and influence on mycobacterial InhA and PknB of 12-membered cyclodepsipeptides.
Bioorg Med Chem
; 26(12): 3166-3190, 2018 07 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-29706526