Detalhe da pesquisa
1.
Structural Basis of Membrane Protein Chaperoning through the Mitochondrial Intermembrane Space.
Cell
; 175(5): 1365-1379.e25, 2018 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30445040
2.
Conformational ensembles of the human intrinsically disordered proteome.
Nature
; 626(8000): 897-904, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-38297118
3.
Plant YTHDF proteins are direct effectors of antiviral immunity against an N6-methyladenosine-containing RNA virus.
EMBO J
; 42(18): e113378, 2023 09 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-37431920
4.
Cryo-EM structure of the human NKCC1 transporter reveals mechanisms of ion coupling and specificity.
EMBO J
; 41(23): e110169, 2022 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36239040
5.
Cancer Mutations of the Tumor Suppressor SPOP Disrupt the Formation of Active, Phase-Separated Compartments.
Mol Cell
; 72(1): 19-36.e8, 2018 10 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30244836
6.
Insights into the conservation and diversification of the molecular functions of YTHDF proteins.
PLoS Genet
; 19(10): e1010980, 2023 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-37816028
7.
Conformational Rigidity and Protein Dynamics at Distinct Timescales Regulate PTP1B Activity and Allostery.
Mol Cell
; 65(4): 644-658.e5, 2017 Feb 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-28212750
8.
PRKN-linked familial Parkinson's disease: cellular and molecular mechanisms of disease-linked variants.
Cell Mol Life Sci
; 81(1): 223, 2024 May 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-38767677
9.
Destabilization and Degradation of a Disease-Linked PGM1 Protein Variant.
Biochemistry
; 63(11): 1423-1433, 2024 Jun 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-38743592
10.
The effect of linker conformation on performance and stability of a two-domain lytic polysaccharide monooxygenase.
J Biol Chem
; 299(11): 105262, 2023 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37734553
11.
Lysine deserts prevent adventitious ubiquitylation of ubiquitin-proteasome components.
Cell Mol Life Sci
; 80(6): 143, 2023 May 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37160462
12.
HSP70-binding motifs function as protein quality control degrons.
Cell Mol Life Sci
; 80(1): 32, 2023 Jan 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-36609589
13.
Accurate model of liquid-liquid phase behavior of intrinsically disordered proteins from optimization of single-chain properties.
Proc Natl Acad Sci U S A
; 118(44)2021 11 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34716273
14.
Mapping the degradation pathway of a disease-linked aspartoacylase variant.
PLoS Genet
; 17(4): e1009539, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33914734
15.
Biophysical and Mechanistic Models for Disease-Causing Protein Variants.
Trends Biochem Sci
; 44(7): 575-588, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30712981
16.
Interpreting the molecular mechanisms of disease variants in human transmembrane proteins.
Biophys J
; 122(11): 2176-2191, 2023 06 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36600598
17.
Assessment of models for calculating the hydrodynamic radius of intrinsically disordered proteins.
Biophys J
; 122(2): 310-321, 2023 01 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-36518077
18.
Rare Catechol-O-methyltransferase Missense Variants Are Structurally Unstable Proteasome Targets.
Biochemistry
; 62(8): 1394-1405, 2023 04 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-36976271
19.
Integrated NMR/Molecular Dynamics Determination of the Ensemble Conformation of a Thermodynamically Stable CUUG RNA Tetraloop.
J Am Chem Soc
; 145(30): 16557-16572, 2023 08 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-37479220
20.
Lynch syndrome, molecular mechanisms and variant classification.
Br J Cancer
; 128(5): 726-734, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36434153