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1.
Rev Med Brux ; 37(3): 135-144, 2016.
Artigo em Francês | MEDLINE | ID: mdl-28525186

RESUMO

BACKGROUND: This retrospective and observational study is based on the hypothesis that sex offenders have experienced trauma and/or educational dysfunction which have a responsibility in theirs crimes of sexual type. The purpose of this study is to highlight these disturbances, develop a typology of sex offenders and offer a reflection on elements which allowed their acting out. METHODS: Two groups were selected. A group of 31 patients having committed criminal offences or murders and having been determined as mentally irresponsibles of their act (" Défense Sociale " in Belgium). This group was compared to a group of 31 patients consulting a general practitioner. A survey and a personal interview were used. Most of this questions came from Thomas Achenbach's Child Behavior Checklist (this questionnaire highlight psychiatric disorders or pathological behaviors in childhood). The inclusion criteria were: male patients major in social defense; single or series rape(s) (accompanied or not by murder); incest; pedophilia; intelligence quotient greater than or equal to 80 (determined by the scale WAIS). RESULTS: The anova test results showed a statistically significant difference between the two groups (p ⟨ 0,00063). Several different profiles of rapists were established. CONCLUSION: Indeed, patient group shows more trauma such as sexual abuse (9.8 times more) and physical abuse (3.1 times more) than the control group. Three factors were identified as a condition to an achieved rape: a pathological family dynamic, impaired impulse control and an empathic deficit.


INTRODUCTION: Cette étude rétrospective et observationnelle se base sur une hypothèse de travail postulant que les délinquants sexuels auraient évolué dans une dynamique familiale pathologique comprenant des dysfonctions éducatives et/ou des éléments traumatiques. Les buts de cette étude sont de mettre en évidence les perturbations familiales qu'ils auraient subies durant l'enfance, d'élaborer une typologie actuelle de ces délinquants en défense sociale et de proposer une réflexion sur les éléments qui ont permis leur passage à l'acte. METHODES: Deux groupes ont été sélectionnés. Le groupe de patients est représenté par 31 AICS (Auteurs d'Infractions à Caractère Sexuel) choisis aléatoirement en Défense Sociale belge en 2013 et ayant répondu à un questionnaire. Ce groupe a été comparé à un autre groupe de 31 patients ayant répondu au même questionnaire anonyme dans la salle d'attente d'un médecin généraliste. Ce questionnaire a été inspiré de la Child Behavior Checklist qui est utilisée pour mettre en évidence des comportements pathologiques de l'enfant et de l'adolescent. Les questions étaient donc ciblées dans leur passé, lorsqu'ils étaient enfants et adolescents. RESULTATS: Le test anova (p ⟨ 0,00063) montre une différence significative des scores entre les deux groupes pour les questions fermées. En effet, le groupe d'AICS présente un score plus élevé dans les paramètres scorés des réponses fermées (plus d'abus sexuels, plus de toxicomanies, etc.). Pour les pédophiles, l'étude a permis de mettre en évidence plusieurs facteurs qui orientent la pulsion sexuelle préférentiellement vers l'enfant plutôt que vers l'adulte. Les violeurs de femmes adultes semblent présenter davantage de traits sadiques. Différents profils d'AICS ont pu être établis. CONCLUSION: Le passage à l'acte du viol met en évidence sur les patients de l'étude trois facteurs nécessaires à son déroulement : une dynamique familiale pathologique, des troubles du contrôle des impulsions et un déficit empathique. Les résultats de cette recherche pourraient permettre d'apporter des informations concernant les différentes étiologies motivant leur passage à l'acte afin de mieux cibler le traitement pour diminuer le risque de récidive.


Assuntos
Comportamento Infantil/psicologia , Criminosos/psicologia , Psiquiatria Legal , Delitos Sexuais/psicologia , Adulto , Bélgica , Criança , Maus-Tratos Infantis , Abuso Sexual na Infância/psicologia , Humanos , Incesto/psicologia , Masculino , Pedofilia/psicologia , Estupro/psicologia , Estudos Retrospectivos
2.
Rev Med Brux ; 37(4): 235-241, 2016.
Artigo em Francês | MEDLINE | ID: mdl-28525221

RESUMO

In Belgium, poor sleep complaints are numerous and frequent in the general population. Of these complaints, one of the most important is insomnia. Acute onset and chronicity of insomnia can be explained by different models based on genetic criteria, neurophysiological, neuroendocrine, neuroimmunological and neuroimaging. Insomnia can be associated with a lot of somatic and psychiatric comorbidities. The diagnosis of insomnia is primarily a clinical diagnosis based on medical history and physical examination. Different tools can help us in our approach, such as self-questionnaires and sleep diaries while additional tests (polysomnography and actigraphy) should be reserved for research of associated sleep disorders and for unclear situations. The management of insomnia can be non-drug treatment (exercise, light therapy, acupuncture and self-treatment cognitive behavioral therapy) but also drug treatment (benzodiazepine, Z-DRUGS, melatonin, antidepressants, herbal medicines, neuroleptics and antihistaminics). Each of these approaches has advantages and disadvantages that must be considered when choosing treatment. The aim of this review is to allow general practitioners to better understand the mechanisms of insomnia and to have recommendations for the diagnosis and treatment of insomnia.


En Belgique, les plaintes de mauvais sommeil sont multiples et fréquentes dans la population générale. Parmi ces plaintes, l'une des plus importantes est l'insomnie. La survenue aiguë et le passage à la chronicité de l'insomnie peuvent être expliqués par différents modèles reposant sur des critères génétiques, neurophysiologiques, neuroendocriniens, neuroimmunologiques et de neuroimageries. L'insomnie peut être associée à de nombreuses comorbidités somatiques et psychiatriques. Le diagnostic de l'insomnie est avant tout un diagnostic clinique reposant sur l'anamnèse médicale et l 'examen physique. Différents outils peuvent nous aider dans notre démarche, tels que les auto-questionnaires et les agendas de sommeil tandis que les examens complémentaires (polysomnographie et actimétrie) sont à réserver à la recherche de pathologies du sommeil associées et pour les situations peu claires. La prise en charge de l'insomnie peut être non médicamenteuse (exercice physique, luminothérapie, acupuncture, auto-traitement et thérapie cognitivocomportementale), mais aussi médicamenteuse (benzodiazépines, Z-DRUGS, mélatonine, antidépresseurs, médicaments à base de plantes, neuroleptiques et antihistaminiques). Chacune de ses approches présente des avantages et des inconvénients dont il faudra tenir compte lors du choix du traitement. Le but de cette revue est de permettre aux médecins généralistes de mieux comprendre les mécanismes de l'insomnie et de disposer de recommandations pour le diagnostic et le traitement de l'insomnie.


Assuntos
Medicina Geral , Distúrbios do Início e da Manutenção do Sono/diagnóstico , Distúrbios do Início e da Manutenção do Sono/terapia , Humanos , Guias de Prática Clínica como Assunto
3.
J Neurophysiol ; 110(1): 162-9, 2013 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-23596336

RESUMO

Previous studies in animals and humans have reported correlations between the durations of rapid eye movement sleep (REMS) episodes and immediately preceding or subsequent non-REMS (NREMS) episodes. The relationship between these two types of sleep is a crucial component in understanding the regulation and neurophysiology of ultradian alternations that occur during sleep. Although the present study replicated previous studies, we also measured NREMS in terms of spectral power Delta and Ultra-Slow bands in addition to duration in examining correlations. The spectral power Delta band, also known as slow-wave activity, measures sleep quantity and is believed to reflect sleep physiology better than mere episode durations. The Ultra-Slow spectral power band was analyzed in parallel. Healthy human participants of both sexes (n = 26, age range 15-45 yr, n = 12 female) were carefully selected to participate in two consecutive series of home polysomnograms performed after 2 nights of habituation to the equipment. In the analyses, REMS episode durations (minutes) were compared with immediately preceding and immediately subsequent NREMS episodes (Delta and Ultra-Slow power) in each sleep cycle. REMS episode duration was more strongly correlated with preceding NREMS episodes than with subsequent NREMS episodes. However, in most cases, no correlations were observed in either direction. One ultradian sleep regulation hypothesis, which is based on stronger correlations between REMS and subsequent NREMS episode durations, holds that the main purpose of REMS is to reactivate NREMS during each sleep cycle. The present results do not support that hypothesis.


Assuntos
Ondas Encefálicas/fisiologia , Sono REM/fisiologia , Adolescente , Adulto , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Adulto Jovem
4.
Rev Med Brux ; 34(2): 90-9, 2013.
Artigo em Francês | MEDLINE | ID: mdl-23755716

RESUMO

The study of the cerebral mechanisms underlying empathy lies currently at the heart of neuroscience research. This process which can be defined as "the ability to put oneself into other's shoes in order to feel his emotions and feelings", constitutes a basic skill in any interpersonal relationship, particularly in the caregiver-patient relationship. In addition, the study of empathy impairements offers new ways to approach diverse mental disorders such as autism or psychopathy. However, it is essential to identify how the brain processes empathy in healthy subjects before studying its impairements. The purpose of this paper will then be to synthesize what the neuroscience research already identified thanks to the numerous works in neurophysiology, neuroimaging and lesion studies. We will also mention some limitations of this field of research and end the paper with its future perspectives.


Assuntos
Empatia , Emoções , Humanos , Neurociências , Pesquisa , Teoria da Mente
5.
Rev Med Brux ; 34(6): 456-61, 2013.
Artigo em Francês | MEDLINE | ID: mdl-24505865

RESUMO

Monitoring parameters for anorexia nervosa include clinical, biological and psychological factors. Many research groups are currently trying to identify parameters more likely to predict the severity or the evolution of the illness. Body composition has been proposed as one of those parameters. The aim of the present study is to demonstrate that measures of body composition are more accurate and efficient than the use of body composition index (BMI). We also aim to show that body composition could be used as a prognostic factor in the long-term evolution of patients with anorexia nervosa. It's a retrospective study investigating body composition and BMI in 44 patients treated in a specialized unit for eating disorder. Measures of body composition and BMI were gathered at the time of admission and again 3 months after refeeding onset. Data was correlated to the EDI-2 questionnaire scores. BMI and %FM where found to be increased (P < 0.05) between admission and after 3 months refeeding. The double objective of reaching a BMI value > or = 20 kg/m2 and a %FM value > or = 2% was achieved by 22% of patients. No significant correlation was found between EDI-2 scores and measures of BMI and %FM either on admission or after the 3 months refeeding period. In conclusion, results of our study don't allow concluding for a prognostic superiority of %FM. Nonetheless, BMI currently used as a reference for the monitoring of eating disorders patients seems to lack sensitivity where measures of body composition seem more informative regarding nutritional status. Furthermore, fat mass plays an important role in other clinical manifestations. In addition, measures of body composition should allow more individualised therapeutic support.


Assuntos
Anorexia Nervosa/diagnóstico , Composição Corporal , Hospitalização , Adolescente , Adulto , Anorexia Nervosa/epidemiologia , Anorexia Nervosa/metabolismo , Anorexia Nervosa/terapia , Impedância Elétrica , Feminino , Hospitalização/estatística & dados numéricos , Humanos , Terapia Nutricional , Estudos Retrospectivos , Adulto Jovem
6.
Rev Med Brux ; 33(2): 75-86, 2012.
Artigo em Francês | MEDLINE | ID: mdl-22812053

RESUMO

Attention-deficit/hyperactivity disorder (ADHD) is a common neuropsychiatric disorder of childhood with a prevalence rate of 5 % among school-age children. This disorder have a strong impact on parent-child relationships. This review synthesizes recent research evidence regarding the rate of child abuse among ADHD children. At least one per 30 chidren have been maltreated in a general population. All authors are asking for better prevention of abuse by a better knowledge of which children are at greater risk of abuse. ADHD children, like children with disabilities, are most frequently maltreated. In this group of children, abuse are often associated with co-occurrence of oppositionnal defiant disorder (ODD) or behavioral difficulties. Maltreated ADHD children have an increased risk of substance use disorders (SUDs) at adolescence. Through this review, we hypothesize about the reasons of an increased risk of abuse by ADHD children. With our clinical experience, we will try to plan prevention and detection strategies about abuse in ADHD children, which have a strong impact on children's pronostic.


Assuntos
Transtorno do Deficit de Atenção com Hiperatividade/complicações , Maus-Tratos Infantis , Pais/psicologia , Transtorno do Deficit de Atenção com Hiperatividade/terapia , Criança , Maus-Tratos Infantis/prevenção & controle , Humanos , Fatores de Risco
7.
Rev Med Brux ; 33(2): 105-10, 2012.
Artigo em Francês | MEDLINE | ID: mdl-22812056

RESUMO

In 1930, Dr Edward Bach developed flower essences known as Bach flowers. Today, over 70 years later, they are becoming more and more popular and are used by many practitioners, despite a total lack of scientific support for their use. A review of the literature on the controversial use of this alternative treatment is discussed.


Assuntos
Flores , Fitoterapia , Extratos Vegetais/uso terapêutico , Humanos
8.
Rev Med Brux ; 32(3): 169-78, 2011.
Artigo em Francês | MEDLINE | ID: mdl-21834446

RESUMO

Despite numbers of publications and effort to try to establish the definition, the classification, the epidemiology, the clinical aspects and the psychopathology of serial killers, a universal consensus seems to say the least. Crime, though reduced in some countries, appears to impact more and more consistent worldwide, generating controversial ideas and a multitude of possible explanations. The serial killer usually presents as a caucasian man, aged between 20 and 40 years, often embedded socially and in his family, but with serious psychiatric, personal and especially family history. Usually acting alone, the serial killer plans a crime well in advance, but sometimes within the scope of impulsivity for a minority, the victim not being previously selected. In the latter case, an actual mental illness like psychosis is found. It is clear from numerous psychopathological studies conducted so far that most serial killers are defined as psychopathic sexual sadists, whose childhood was difficult, if not flouted, punctuated by physical and psychological violence situations. In addition, pervasive fantasies combined with thoughts of death, sex and violence are as much in common with the original acts of which they are the instigators. Beyond a relentless media that is constantly watering the public with stories and pictures depicting them as such, serial killers remain an enigma. We can therefore attempt to answer the various questions raised by this phenomenon, the way these people operate and how we can curb the rise, thanks to the neurobiological and neurophysiological approaches that science offers us.


Assuntos
Homicídio , Transtornos Mentais , Humanos
9.
Rev Med Brux ; 32(3): 158-68, 2011.
Artigo em Francês | MEDLINE | ID: mdl-21834445

RESUMO

Psychopathy related research has traditionally focused on males. Today, numerous evidences testify to the existence of the disorder in women. Nevertheless the possibility to transpose this concept unchanged to women is debated, as it was initially developed in male populations. Current researches didn't notice major gender differences in the structure of the disorder. Nevertheless, one note differences in the prevalence measurement and in the mean score of psychopathy according to usual diagnostic scales. The prevalence rates are generally lower among women, and men seem to have higher mean scores on psychopathy measures. Furthermore, man and woman share most of interpersonal and affective traits as well as psychopathic behaviours, but they may rely on different tactics to achieve the same goals. Considering these differences, the increase of the female criminality speaks to the need for understanding more the construct of the disorder in women, for validating results already obtained with larger samples and for developing objective and adapted evaluating instruments to predict reliably reoffends, institutional structures and treatment response. Secondly it would be interesting to enlighten early factors that may affect, predict or moderate the expression of the disorder, in a preventive goal.


Assuntos
Transtorno da Personalidade Antissocial , Transtorno da Personalidade Antissocial/diagnóstico , Feminino , Humanos , Prevalência
10.
Rev Med Brux ; 32(5): 459-72, 2011.
Artigo em Francês | MEDLINE | ID: mdl-22165524

RESUMO

Young women are at risk of mental problem during pregnancy and postpartum. It is particularly important that the mental health of childbearing women is stable. However, all psychotropic medications diffuse across the placenta and are excreted into breast milk. The fetus is thus at risk of teratogenicity and postnatal behavioural sequelae. Which are today the psychotropics that can take up the challenge of minimizing the risk for the foetus and at the same time limiting the impact of morbidity on the mother ? Medical literature of last ten years is reviewed. The safety issue of psychotropic's use during pregnancy and lactation is still unresolved. Little information is available concerning developmental outcome of children exposed to medication, especially about newer molecules even though recent case reports are encouraging. Larger standardized studies are still needed.


Assuntos
Deficiências do Desenvolvimento/induzido quimicamente , Troca Materno-Fetal , Psicotrópicos/farmacocinética , Aleitamento Materno/efeitos adversos , Feminino , Humanos , Lactente , Lactação , Gravidez , Efeitos Tardios da Exposição Pré-Natal , Psicotrópicos/efeitos adversos
11.
Acta Psychiatr Scand ; 121(3): 236-9, 2010 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-19764928

RESUMO

OBJECTIVE: Major depressive disorder (MDD), which is associated with altered neuroplasticity and increased relative cardiac sympathic activity, enhances the risk of cardiovascular pathologies. Interaction between cardiac sympatho-vagal indexes and delta sleep power is probably altered in MDD. METHOD: Sleep characteristics and cardiac sympatho-vagal indexes of 10 depressive patients were compared to 10 control men across the first three non-rapid eye movement (NREM)-REM cycles. Interaction between normalized high frequency (HF) and delta power bands was studied using coherence analysis. RESULTS: Patients showed increased sleep latency, stage 1 and wake durations. No differences in heart rate variabilities were observed: Total power, HF and RR-interval decreased from NREM to REM sleep and wakefulness in both groups. Gain value was lower in patients while coherence and phase shift were similar between groups. Modifications in HF appear 8 min before modifications in delta. CONCLUSION: Major depressive disorder is related to an altered link between cardiac vagal influence and delta sleep, suggesting disorders in cardiovascular controls and an altered neuroplasticity.


Assuntos
Ritmo Delta/psicologia , Transtorno Depressivo Maior/fisiopatologia , Coração/fisiologia , Sono REM/fisiologia , Adulto , Pressão Sanguínea/fisiologia , Estudos de Casos e Controles , Transtorno Depressivo Maior/etiologia , Transtorno Depressivo Maior/psicologia , Eletrocardiografia , Eletroencefalografia , Movimentos Oculares/fisiologia , Frequência Cardíaca/fisiologia , Humanos , Masculino , Pessoa de Meia-Idade , Plasticidade Neuronal , Vigília/fisiologia , Adulto Jovem
12.
Rev Med Brux ; 30(6): 577-87, 2009.
Artigo em Francês | MEDLINE | ID: mdl-20545071

RESUMO

Although psychopathy has traditionally been cited as a disorder of personality, confusion arises as the term is used interchangeably with the terms antisocial personality disorder of the Diagnostic and Statistical Manual of Mental Disorders, fourth edition, text revision (DSM-IV TR) or dissocial personality disorder, both of which are largely behaviorally based. This paper aims to provide a clinical and scientific overview of the literature on the topic of psychopathy, which examines this conundrum. This article begins with a wee bit of history about Hervey Cleckley's work, The Mask of Sanity, and then presents the definitions and nosography of psychopathy, focusing on the distinction between the antisocial psychopath and the successful psychopath. The discussion will then lead on the epidemiological aspects and diagnosis, especially psychometric and measurement tools used to assess psychopathy in the individual: Hare's Psychopathy Checklist-Revised (PCL-R), as this is the most frequently used and validated measure of psychopathy. The second section of the article reviews several studies dealing with structural and functional neuroimaging in psychopaths. The final part of this overview considers the treatment and interventions that are available to psychopathic offenders and the implications for future research, especially in terms of prevention. This review demonstrates that studies and further research are still required in psychopathy, particularly using functional neuroimaging techniques, as fMRI and magnetoencephalography, that can describe the functional neuroanatomy of human emotion. Today, cognitive and social neurosciences constitute one of the most promising way to study psychopathy.


Assuntos
Transtorno da Personalidade Antissocial/psicologia , Neurociências/tendências , Comportamento Social , Transtorno da Personalidade Antissocial/classificação , Transtorno da Personalidade Antissocial/diagnóstico , Transtorno da Personalidade Antissocial/epidemiologia , Encéfalo/patologia , Transtornos Cognitivos/etiologia , Manual Diagnóstico e Estatístico de Transtornos Mentais , Humanos , Imageamento por Ressonância Magnética , Transtornos do Humor/etiologia , Personalidade
13.
Epidemiol Psychiatr Sci ; 29: e33, 2019 Apr 22.
Artigo em Inglês | MEDLINE | ID: mdl-31006419

RESUMO

AIMS: The Resilience Scale for Adults (RSA) is a questionnaire that measures protective factors of mental health. The aim of this paper is to perform a network analysis of the RSA in a dataset composed of 675 French-speaking Belgian university students, to identify potential targets for intervention to improve protective factors in individuals. METHODS: We estimated a network structure for the 33-item questionnaire and for the six domains of resilience: perception of self, planned future, social competence, structured style, family cohesion and social competence. Node predictability (shared variance with surrounding nodes in the network) was used to assess the connectivity of items. An exploratory graph analysis (EGA) was performed to detect communities in the network: the number of communities detected being different than the original number of factors proposed in the scale, we estimated a new network with the resulting structure and verified the validity of the new construct which was proposed. We provide the anonymised dataset and code in external online materials (10.17632/64db36w8kf.2) to ensure complete reproducibility of the results. RESULTS: The network composed of items from the RSA is overall positively connected with strongest connections arising among items from the same domain. The domain network reports several connections, both positive and negative. The EGA reported the existence of four communities that we propose as an additional network structure. Node predictability estimates show that connectedness varies among the items and domains of the RSA. CONCLUSIONS: Network analysis is a useful tool to explore resilience and identify targets for clinical intervention. In this study, the four domains acting as components of the additional four-domain network structure may be potential targets to improve an individual's resilience. Further studies may endeavour to replicate our findings in different samples.


Assuntos
Resiliência Psicológica , Estudantes/psicologia , Inquéritos e Questionários , Adolescente , Adulto , Bélgica , Análise Fatorial , Feminino , Humanos , Masculino , Psicometria , Reprodutibilidade dos Testes , Estudantes/estatística & dados numéricos , Universidades , Adulto Jovem
14.
Encephale ; 34(2): 139-45, 2008 Apr.
Artigo em Francês | MEDLINE | ID: mdl-18597721

RESUMO

BACKGROUND: In the context of the increasing interest in the study and assessment of emotional abilities in psychology, we translated into French and evaluated the construct validity of the emotional intelligence inventory (EII) designed in English [Psychol Rep; 88 (2001):353-64]. This self-rating scale is modelled along the theoretical constructs of the Mayer, Caruso and Salovey's model [Intelligence; 27 (1999):267-98]; it comprises 41 items tapping the four following factors: (1) empathy; (2) utilization of feelings, (3) handling relationships and; (4) self-control. METHODS: One thousand three hundred and thirty-five students (42.7% men) with a mean age of 19.6 years and affiliated to several school and faculties participated to this Belgian interuniversity study. They were administered the French version of the EII, as well as a series of related questionnaires. Confirmatory factor analyses (CFA) were applied to these data and various fit indices examined in order to assess the factorial adjustment to the data of the four-factor a priori structure. RESULTS: CFA did not support the original 41-item four-factor structure for the scale in French, but a good statistical fit to the data could be obtained with the reduction of the scale to 20 items. The content of the resulting item set, keeping Tapia's four factors, encourages a revision of the domain covered by the subscales. CONCLUSION: Further efforts should be directed at assessing the content validity of the proposed revised scale as a reliable tool in measuring emotional intelligence by self-report.


Assuntos
Afeto , Inteligência , Idioma , Inquéritos e Questionários , Adolescente , Adulto , Análise Fatorial , Feminino , França , Humanos , Masculino , Reprodutibilidade dos Testes
15.
Neuroscience ; 148(3): 782-93, 2007 Sep 07.
Artigo em Inglês | MEDLINE | ID: mdl-17693033

RESUMO

OBJECTIVE: The aim of the present study is to investigate the scaling properties of the sleep electroencephalogram (EEG) in remitted depressed men, and to evaluate if a past history of major depressive disorder (MDD) could modify significantly and definitively, as a "scar marker," the dynamics of the sleep EEG time series. METHODOLOGY: Whole night sleep electroencephalogram signals were recorded in 24 men: 10 untreated depressed men in full to partial remission (42.43+/-5.62 years) and 14 healthy subjects (42.8+/-8.55 years). Scaling properties in these time series were investigated with detrended fluctuation analysis (DFA) (time range: 0.16-2.00 s). The scaling exponent alpha was determined in stage 2, in slow wave sleep (stages 3 and 4), and during rapid eye movement (REM) sleep. Forty-five epochs of 20 s were chosen randomly in each of these stages for each subject in both groups. RESULTS: We did not observe a significant difference and deviation of the scaling exponents between the two groups during the three sleep stages of interest. CONCLUSION: In this study, we do not observe any functional sequelae of a past history of one or more unipolar major depressive episode on the fluctuation properties of the sleep EEG. This finding is a sign of similar underlying neuronal dynamics in healthy controls and patients with a lifetime history of MDD. This study gives an additional argument to the theory that depression does not modify definitively the dynamics of the neuronal networks and is therefore against the "depressive scar hypothesis," in which permanent residual deficit is created by the acute state of the depressive disease.


Assuntos
Córtex Cerebral/fisiopatologia , Transtorno Depressivo/complicações , Transtorno Depressivo/fisiopatologia , Eletroencefalografia , Transtornos do Sono-Vigília/etiologia , Transtornos do Sono-Vigília/fisiopatologia , Sono/fisiologia , Potenciais de Ação/fisiologia , Adulto , Biomarcadores , Humanos , Pessoa de Meia-Idade , Rede Nervosa/fisiopatologia , Neurônios/fisiologia , Recuperação de Função Fisiológica/fisiologia , Sono REM/fisiologia , Tempo , Fatores de Tempo
16.
Clin Neurophysiol ; 118(4): 940-50, 2007 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-17314064

RESUMO

OBJECTIVE: The aim of the present paper is to study the fluctuations of the sleep EEG over various time scales during a specific pathological condition: major depressive episode. Focus is made on scaling behaviour, which is the signature of the absence of characteristic time scale, and the presence of long-range correlations associated to physiological constancy preservation, variability reduction and mostly adaptability. METHODS: Whole night sleep electroencephalogram signals were recorded in 24 men: 10 untreated patients with a major depressive episode (41.70+/-8.11 years) and 14 healthy subjects (42.43+/-5.67 years). Scaling in these time series was investigated with detrended fluctuation analysis (time range: 0.16-2.00s). Scaling exponents (alpha) were determined in stage 2, slow wave sleep (stages 3 and 4) and during REM sleep. Forty-five epochs of 20s were chosen randomly in each of these stages. RESULTS: The median values of alpha were lower in patients during stage 2 and SWS. CONCLUSIONS: Major depressive episodes are characterized by a modification in the correlation structure of the sleep EEG time series. The finding which shows decreasing rate of the temporal correlations being different within the two groups in stage 2 and SWS provides an electrophysiologic argument that the underlying neuronal dynamics are modified during acute depression. SIGNIFICANCE: The observed modifications in scaling behaviour in acutely depressed patients could be an explanation of the sleep fragmentation and instability found during major depressive episode.


Assuntos
Depressão/fisiopatologia , Eletroencefalografia , Sono/fisiologia , Adulto , Humanos , Masculino , Pessoa de Meia-Idade , Dinâmica não Linear , Polissonografia , Processamento de Sinais Assistido por Computador
17.
Rev Med Brux ; 28(3): 191-3, 2007.
Artigo em Francês | MEDLINE | ID: mdl-17708476

RESUMO

We report on a sleepy woman, suffering from morbid obesity, with a diagnosis of severe sleep apnea syndrome made at the age of 30 year, treated with nocturnal ventilatory support (nasal CPAP). The patient had an history of preeclampsia during a first pregnancy. In the following years, this patient remained very compliant with nasal CPAP, was no longer sleepy and was three times pregnant, without any complication.


Assuntos
Pressão Positiva Contínua nas Vias Aéreas/métodos , Obesidade Mórbida/complicações , Complicações na Gravidez/terapia , Síndromes da Apneia do Sono/terapia , Adulto , Feminino , Humanos , Obesidade Mórbida/terapia , Cooperação do Paciente , Pré-Eclâmpsia/prevenção & controle , Gravidez
18.
Rev Med Brux ; 28(1): 33-8, 2007.
Artigo em Francês | MEDLINE | ID: mdl-17427677

RESUMO

The concept of resilience refers to the capacity of certain individuals either to adapt successfully to adversity, or to function in a competent manner when faced with a traumatic situation. The concept of resilience represents a new paradigm in the field of clinical psychology. It puts into perspective determinist models, whether they be psychological (experiences incurred during the first years of life forever seal the destiny of a subject) or biological (an individual is defined by his/her genes). It permits the study of an individual according to his/her resources and no longer according to his/her faults. Nevertheless, for several years, resilience has suffered from its own success by being frequently used in inappropriate contexts. With the aim of better understanding this concept and of avoiding its determinist and normative distortion, we present here a review of the different factors (psychological, family, sociological and biological factors) contributing to the process of resilience. Moreover, in the discussion, we present some methodological and conceptual issues presented by the concept of resilience.


Assuntos
Adaptação Psicológica , Estresse Psicológico , Família , Feminino , Humanos , Controle Interno-Externo , Acontecimentos que Mudam a Vida , Masculino , Estresse Psicológico/prevenção & controle
19.
Rev Med Brux ; 28(1): 11-20, 2007.
Artigo em Francês | MEDLINE | ID: mdl-17427674

RESUMO

Nowadays, a high percentage of the population in modern societies suffers from various kinds of sleep disturbances, in part due to the impact of increased socio-cultural stress factors. The most common sleep complaint is insomnia. Psychophysiological insomnia is one of the most frequent forms of sleep disturbances. It is a type of conditioned or learned insomnia that is presumably derived from two sources. The first involves the conditioning of sleep-preventing habits in which repeated pairing of sleeplessness and situational, temporal, or behavioural stimuli normally associated with sleep leads to conditional arousal that impairs sleep. The second involves somatised tension believed to result from the internalisation of psychological conflicts and excessive worrying about sleep, which are incompatible with sleep. Quantitative EEG approach, particularly with spectral analysis, has recently refined the analysis of the EEG in sleep. These EEG quantification techniques are now very useful to understand the neurophysiological basis of a lot of sleep disorders, particularly in the case of psychophysiological insomnia.


Assuntos
Distúrbios do Início e da Manutenção do Sono/fisiopatologia , Distúrbios do Início e da Manutenção do Sono/psicologia , Ansiedade , Nível de Alerta , Eletroencefalografia , Humanos , Aprendizagem , Transtornos do Sono-Vigília/fisiopatologia , Transtornos do Sono-Vigília/psicologia
20.
Med Eng Phys ; 28(2): 156-65, 2006 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-15939658

RESUMO

Spectral analysis is now a standard procedure for analyzing the electroencephalograms (EEG) obtained by polysomnographic recordings. These numerical methods assume an artifact-free EEG since artifacts create spurious spectral components. Our aim was the development of a QRS artifact removal technique that might be applied to full night EEG with a minimal human intervention. This technique should handle one EEG channel, with or without use of one ECG channel. Variance minimization, independent component analysis (ICA), morphological filters (MF) have been implemented. Careful attention has been given to define the MF structuring element. The tests on artifact-simulated and real data were checked on the residual ECG spectral components present in the cleaned EEG. The best results are obtained by the MF when the structuring element is an artifact template defined either directly on the EEG or on the ICA ECG component. Further developments are required to identify and subtract the T-wave artifacts.


Assuntos
Algoritmos , Artefatos , Encéfalo/fisiologia , Diagnóstico por Computador/métodos , Eletrocardiografia/métodos , Eletroencefalografia/métodos , Polissonografia/métodos , Humanos , Processamento de Sinais Assistido por Computador
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