Detalhe da pesquisa
1.
F901318 represents a novel class of antifungal drug that inhibits dihydroorotate dehydrogenase.
Proc Natl Acad Sci U S A
; 113(45): 12809-12814, 2016 Nov 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27791100
2.
Pharmacodynamics of the Novel Antifungal Agent F901318 for Acute Sinopulmonary Aspergillosis Caused by Aspergillus flavus.
J Infect Dis
; 217(7): 1118-1127, 2018 03 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-28968675
3.
Pharmacodynamics of Voriconazole for Invasive Pulmonary Scedosporiosis.
Antimicrob Agents Chemother
; 62(5)2018 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29439967
4.
Repurposing and Reformulation of the Antiparasitic Agent Flubendazole for Treatment of Cryptococcal Meningoencephalitis, a Neglected Fungal Disease.
Antimicrob Agents Chemother
; 62(4)2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29311092
5.
Experimental Models of Short Courses of Liposomal Amphotericin B for Induction Therapy for Cryptococcal Meningitis.
Antimicrob Agents Chemother
; 61(6)2017 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28320715
6.
Pharmacodynamics of Isavuconazole in a Dynamic In Vitro Model of Invasive Pulmonary Aspergillosis.
Antimicrob Agents Chemother
; 60(1): 278-87, 2016 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26503648
7.
Pharmacodynamics of liposomal amphotericin B and flucytosine for cryptococcal meningoencephalitis: safe and effective regimens for immunocompromised patients.
J Infect Dis
; 208(2): 351-61, 2013 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23599314
8.
Pharmacokinetics and pharmacodynamics of fluconazole for cryptococcal meningoencephalitis: implications for antifungal therapy and in vitro susceptibility breakpoints.
Antimicrob Agents Chemother
; 57(6): 2793-800, 2013 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-23571544
9.
Anidulafungin for neonatal hematogenous Candida meningoencephalitis: identification of candidate regimens for humans using a translational pharmacological approach.
Antimicrob Agents Chemother
; 56(2): 708-14, 2012 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-22123680
10.
Pharmacodynamics of echinocandins against Candida glabrata: requirement for dosage escalation to achieve maximal antifungal activity in neutropenic hosts.
Antimicrob Agents Chemother
; 55(10): 4880-7, 2011 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-21807969
11.
Pharmacodynamics of the Orotomides against Aspergillus fumigatus: New Opportunities for Treatment of Multidrug-Resistant Fungal Disease.
mBio
; 8(4)2017 08 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-28830945
12.
Efficacy of an abbreviated induction regimen of amphotericin B deoxycholate for cryptococcal meningoencephalitis: 3 days of therapy is equivalent to 14 days.
mBio
; 5(1): e00725-13, 2014 Jan 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-24473125
13.
Evaluation of the pharmacokinetics and clinical utility of isavuconazole for treatment of invasive fungal infections.
Expert Opin Drug Metab Toxicol
; 8(6): 759-65, 2012 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-22530880
14.
The Aspergillus fumigatus dihydroxyacid dehydratase Ilv3A/IlvC is required for full virulence.
PLoS One
; 7(9): e43559, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-23028460