1.
RSC Adv
; 9(55): 32210-32218, 2019 Oct 07.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35530773
RESUMO
An archazolid natural product fragment that displays dose-dependent inhibition of the vacuolar-type ATPase (VATPase) has been synthesized by a high-yielding Suzuki coupling of two complex subunits. Similarly, a further simplified fragment was prepared and evaluated for VATPase inhibitory activity. This compound did inhibit the VATPase, as evidenced by growth inhibition of etiolated Arabidopsis seedlings, however at approximately 10× lower potency than the more complex fragment. Cyclooxygenase (COX) enzyme inhibition was not observed for either fragment.
2.
RSC Adv
; 9(60): 34963, 2019 Oct 28.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35532435
RESUMO
[This corrects the article DOI: 10.1039/C9RA07050H.].