Detalhe da pesquisa
1.
Factor XI Inhibition for the Prevention of Catheter-Associated Thrombosis in Patients With Cancer Undergoing Central Line Placement: A Phase 2 Clinical Trial.
Arterioscler Thromb Vasc Biol
; 44(1): 290-299, 2024 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37970718
2.
Role of platelet count in a murine stasis model of deep vein thrombosis.
Platelets
; 35(1): 2290916, 2024 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-38099327
3.
The contact activation inhibitor AB023 in heparin-free hemodialysis: results of a randomized phase 2 clinical trial.
Blood
; 138(22): 2173-2184, 2021 12 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34086880
4.
Factor XII plays a pathogenic role in organ failure and death in baboons challenged with Staphylococcus aureus.
Blood
; 138(2): 178-189, 2021 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33598692
5.
Cross-Talk between the Complement Pathway and the Contact Activation System of Coagulation: Activated Factor XI Neutralizes Complement Factor H.
J Immunol
; 206(8): 1784-1792, 2021 04 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33811105
6.
The protein C activator AB002 rapidly interrupts thrombus development in baboons.
Blood
; 135(9): 689-699, 2020 02 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-31977000
7.
Role of platelets in regulating activated coagulation factor XI activity.
Am J Physiol Cell Physiol
; 320(3): C365-C374, 2021 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33471623
8.
Contact Activation Inhibitor and Factor XI Antibody, AB023, Produces Safe, Dose-Dependent Anticoagulation in a Phase 1 First-In-Human Trial.
Arterioscler Thromb Vasc Biol
; 39(4): 799-809, 2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30700130
9.
Activation of coagulation FXI promotes endothelial inflammation and amplifies platelet activation in a nonhuman primate model of hyperlipidemia.
Res Pract Thromb Haemost
; 8(1): 102276, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-38226339
10.
Pharmacological targeting of coagulation factor XI mitigates the development of experimental atherosclerosis in low-density lipoprotein receptor-deficient mice.
J Thromb Haemost
; 19(4): 1001-1017, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33421301
11.
Heterogeneous ventricular sympathetic innervation, altered beta-adrenergic receptor expression, and rhythm instability in mice lacking the p75 neurotrophin receptor.
Am J Physiol Heart Circ Physiol
; 298(6): H1652-60, 2010 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-20190098
12.
The contact activation system as a potential therapeutic target in patients with COVID-19.
Res Pract Thromb Haemost
; 4(4): 500-505, 2020 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-32542210
13.
Antibody inhibition of contact factor XII reduces platelet deposition in a model of extracorporeal membrane oxygenator perfusion in nonhuman primates.
Res Pract Thromb Haemost
; 4(2): 205-216, 2020 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-32110750
14.
Inhibition of contact-mediated activation of factor XI protects baboons against S aureus-induced organ damage and death.
Blood Adv
; 3(4): 658-669, 2019 02 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-30808684
15.
Regulation of cardiac innervation and function via the p75 neurotrophin receptor.
Auton Neurosci
; 140(1-2): 40-8, 2008 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-18430612
16.
BMP7-induced dendritic growth in sympathetic neurons requires p75(NTR) signaling.
Dev Neurobiol
; 76(9): 1003-13, 2016 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-26663679
17.
Priming with BTCP, a dopamine reuptake blocker, reinstates cocaine-seeking and enhances cocaine cue-induced reinstatement.
Pharmacol Biochem Behav
; 82(1): 46-54, 2005 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-16099021
18.
3-OH-pip-BTCP, a metabolite of the potent DA uptake blocker BTCP, exerts cocaine-like action in rats.
Neuroreport
; 14(18): 2439-44, 2003 Dec 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-14663207
19.
Sympathetic denervation of peri-infarct myocardium requires the p75 neurotrophin receptor.
Exp Neurol
; 249: 111-9, 2013 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-24013014
20.
Factor XI contributes to myocardial ischemia-reperfusion injury in mice.
Blood Adv
; 2(2): 85-88, 2018 01 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-29365314