Detalhe da pesquisa
1.
Discovery of florylpicoxamid, a mimic of a macrocyclic natural product.
Bioorg Med Chem
; 50: 116455, 2021 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34757295
2.
In vivo activation of latent HIV with a synthetic bryostatin analog effects both latent cell "kick" and "kill" in strategy for virus eradication.
PLoS Pathog
; 13(9): e1006575, 2017 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-28934369
3.
Simplified Bryostatin Analogues Protect Cells from Chikungunya Virus-Induced Cell Death.
J Nat Prod
; 79(4): 675-9, 2016 Apr 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-26900625
4.
Toward a biorelevant structure of protein kinase C bound modulators: design, synthesis, and evaluation of labeled bryostatin analogues for analysis with rotational echo double resonance NMR spectroscopy.
J Am Chem Soc
; 137(10): 3678-85, 2015 Mar 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-25710634
5.
Design, synthesis, and evaluation of potent bryostatin analogs that modulate PKC translocation selectivity.
Proc Natl Acad Sci U S A
; 108(17): 6721-6, 2011 Apr 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-21415363
6.
Translating Nature's Library: The Bryostatins and Function-Oriented Synthesis.
Isr J Chem
; 51(3-4): 453-472, 2011 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22661768
7.
REDOR NMR Reveals Multiple Conformers for a Protein Kinase C Ligand in a Membrane Environment.
ACS Cent Sci
; 4(1): 89-96, 2018 Jan 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-29392180
8.
Characterization of designed, synthetically accessible bryostatin analog HIV latency reversing agents.
Virology
; 520: 83-93, 2018 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29800728
9.
Designed, synthetically accessible bryostatin analogues potently induce activation of latent HIV reservoirs in vitro.
Nat Chem
; 4(9): 705-10, 2012 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-22914190