Detalhe da pesquisa
1.
Attenuation hotspots in neurotropic human astroviruses.
PLoS Biol
; 21(7): e3001815, 2023 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37459343
2.
Serendipitous Identification of a Covalent Activator of Liver Pyruvate Kinase.
Chembiochem
; 24(1): e202200339, 2023 01 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36250581
3.
Semliki Forest Virus Chimeras with Functional Replicase Modules from Related Alphaviruses Survive by Adaptive Mutations in Functionally Important Hot Spots.
J Virol
; 95(20): e0097321, 2021 09 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-34319778
4.
Timeliness of Proteolytic Events Is Prerequisite for Efficient Functioning of the Alphaviral Replicase.
J Virol
; 92(14)2018 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29695431
5.
Wolbachia Blocks Viral Genome Replication Early in Infection without a Transcriptional Response by the Endosymbiont or Host Small RNA Pathways.
PLoS Pathog
; 12(4): e1005536, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-27089431
6.
Assembly of Replication-Incompetent African Horse Sickness Virus Particles: Rational Design of Vaccines for All Serotypes.
J Virol
; 90(16): 7405-7414, 2016 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27279609
7.
Mutations conferring a noncytotoxic phenotype on chikungunya virus replicons compromise enzymatic properties of nonstructural protein 2.
J Virol
; 89(6): 3145-62, 2015 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-25552719
8.
Bindarit, an inhibitor of monocyte chemotactic protein synthesis, protects against bone loss induced by chikungunya virus infection.
J Virol
; 89(1): 581-93, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25339772
9.
Functional cross-talk between distant domains of chikungunya virus non-structural protein 2 is decisive for its RNA-modulating activity.
J Biol Chem
; 289(9): 5635-53, 2014 Feb 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-24407286
10.
Novel attenuated Chikungunya vaccine candidates elicit protective immunity in C57BL/6 mice.
J Virol
; 88(5): 2858-66, 2014 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-24371047
11.
Prime-boost immunization strategies against Chikungunya virus.
J Virol
; 88(22): 13333-43, 2014 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-25210177
12.
RIG-I and MDA-5 detection of viral RNA-dependent RNA polymerase activity restricts positive-strand RNA virus replication.
PLoS Pathog
; 9(9): e1003610, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-24039580
13.
A pathogenic role for CD4+ T cells during Chikungunya virus infection in mice.
J Immunol
; 190(1): 259-69, 2013 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23209328
14.
Presentation overrides specificity: probing the plasticity of alphaviral proteolytic activity through mutational analysis.
J Virol
; 87(18): 10207-20, 2013 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-23864614
15.
Magnetic fractionation and proteomic dissection of cellular organelles occupied by the late replication complexes of Semliki Forest virus.
J Virol
; 87(18): 10295-312, 2013 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-23864636
16.
Macromolecular assembly-driven processing of the 2/3 cleavage site in the alphavirus replicase polyprotein.
J Virol
; 86(1): 553-65, 2012 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-22031949
17.
Virus replicon particle based Chikungunya virus neutralization assay using Gaussia luciferase as readout.
Virol J
; 10: 235, 2013 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23855906
18.
Tuning liver pyruvate kinase activity up or down with a new class of allosteric modulators.
Eur J Med Chem
; 250: 115177, 2023 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36753880
19.
Acetylation regulates the oligomerization state and activity of RNase J, the Helicobacter pylori major ribonuclease.
Nat Commun
; 14(1): 8072, 2023 Dec 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-38057323
20.
Structure-Guided Chemical Optimization of Bicyclic Peptide (Bicycle) Inhibitors of Angiotensin-Converting Enzyme 2.
J Med Chem
; 66(14): 9881-9893, 2023 07 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-37433017