Detalhe da pesquisa
1.
Identification and targeting of a unique NaV1.7 domain driving chronic pain.
Proc Natl Acad Sci U S A
; 120(32): e2217800120, 2023 08 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37498871
2.
A light-gated potassium channel for sustained neuronal inhibition.
Nat Methods
; 15(11): 969-976, 2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30377377
3.
Mechanism, and treatment of anti-CV2/CRMP5 autoimmune pain.
bioRxiv
; 2024 May 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-38766071
4.
Targeting the vascular endothelial growth factor A/neuropilin 1 axis for relief of neuropathic pain.
Pain
; 164(7): 1473-1488, 2023 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36729125
5.
SARS-CoV-2 spike protein co-opts VEGF-A/neuropilin-1 receptor signaling to induce analgesia.
Pain
; 162(1): 243-252, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33009246
6.
Selective targeting of NaV1.7 via inhibition of the CRMP2-Ubc9 interaction reduces pain in rodents.
Sci Transl Med
; 13(619): eabh1314, 2021 11 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34757807
7.
SARS-CoV-2 Spike protein co-opts VEGF-A/Neuropilin-1 receptor signaling to induce analgesia.
bioRxiv
; 2020 Sep 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-32869019
8.
1-O-Acetylgeopyxin A, a derivative of a fungal metabolite, blocks tetrodotoxin-sensitive voltage-gated sodium, calcium channels and neuronal excitability which correlates with inhibition of neuropathic pain.
Mol Brain
; 13(1): 73, 2020 05 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32393368
9.
A modulator of the low-voltage-activated T-type calcium channel that reverses HIV glycoprotein 120-, paclitaxel-, and spinal nerve ligation-induced peripheral neuropathies.
Pain
; 161(11): 2551-2570, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32541387
10.
Cdk5-mediated CRMP2 phosphorylation is necessary and sufficient for peripheral neuropathic pain.
Neurobiol Pain
; 52019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31080913
11.
(-)-Hardwickiic Acid and Hautriwaic Acid Induce Antinociception via Blockade of Tetrodotoxin-Sensitive Voltage-Dependent Sodium Channels.
ACS Chem Neurosci
; 10(3): 1716-1728, 2019 03 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-30525440
12.
Targeting the CaVα-CaVß interaction yields an antagonist of the N-type CaV2.2 channel with broad antinociceptive efficacy.
Pain
; 160(7): 1644-1661, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30933958
13.
Reversal of Peripheral Neuropathic Pain by the Small-Molecule Natural Product Physalin F via Block of CaV2.3 (R-Type) and CaV2.2 (N-Type) Voltage-Gated Calcium Channels.
ACS Chem Neurosci
; 10(6): 2939-2955, 2019 06 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-30946560
14.
Betulinic acid, derived from the desert lavender Hyptis emoryi, attenuates paclitaxel-, HIV-, and nerve injury-associated peripheral sensory neuropathy via block of N- and T-type calcium channels.
Pain
; 160(1): 117-135, 2019 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-30169422
15.
CRMP2 is necessary for Neurofibromatosis type 1 related pain.
Channels (Austin)
; 12(1): 47-50, 2018 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28837387
16.
CRMP2-Neurofibromin Interface Drives NF1-related Pain.
Neuroscience
; 381: 79-90, 2018 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29655575
17.
Homology-guided mutational analysis reveals the functional requirements for antinociceptive specificity of collapsin response mediator protein 2-derived peptides.
Br J Pharmacol
; 175(12): 2244-2260, 2018 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28161890
18.
Dissecting the role of the CRMP2-neurofibromin complex on pain behaviors.
Pain
; 158(11): 2203-2221, 2017 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-28767512
19.
CRISPR/Cas9 editing of Nf1 gene identifies CRMP2 as a therapeutic target in neurofibromatosis type 1-related pain that is reversed by (S)-Lacosamide.
Pain
; 158(12): 2301-2319, 2017 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-28809766
20.
Isolation of Mouse Coronary Endothelial Cells.
J Vis Exp
; (113)2016 07 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-27404385