Pesquisa | Portal de Pesquisa da BVS Enfermagem

1.

Macrodomain-containing proteins: regulating new intracellular functions of mono(ADP-ribosyl)ation.

Feijs, Karla L H; Forst, Alexandra H; Verheugd, Patricia; Lüscher, Bernhard.

Nat Rev Mol Cell Biol ; 14(7): 443-51, 2013 Jul.

Artigo em Inglês | MEDLINE | ID: mdl-23736681

2.

Learning how to read ADP-ribosylation.

Kleine, Henning; Lüscher, Bernhard.

Cell ; 139(1): 17-9, 2009 Oct 02.

Artigo em Inglês | MEDLINE | ID: mdl-19804746

3.

Mono-ADP-ribosylation by PARP10 inhibits Chikungunya virus nsP2 proteolytic activity and viral replication.

Krieg, Sarah; Pott, Fabian; Potthoff, Laura; Verheirstraeten, Maud; Bütepage, Mareike; Golzmann, Alexandra; Lippok, Barbara; Goffinet, Christine; Lüscher, Bernhard; Korn, Patricia.

Cell Mol Life Sci ; 80(3): 72, 2023 Feb 25.

Artigo em Inglês | MEDLINE | ID: mdl-36840772

4.

Induction of senescence upon loss of the Ash2l core subunit of H3K4 methyltransferase complexes.

Bochynska, Agnieszka; Stenzel, Alexander T; Sayadi Boroujeni, Roksaneh; Kuo, Chao-Chung; Barsoum, Mirna; Liang, Weili; Bussmann, Philip; Costa, Ivan G; Lüscher-Firzlaff, Juliane; Lüscher, Bernhard.

Nucleic Acids Res ; 50(14): 7889-7905, 2022 08 12.

Artigo em Inglês | MEDLINE | ID: mdl-35819198

5.

Intracellular mono-ADP-ribosyltransferases at the host-virus interphase.

Lüscher, Bernhard; Verheirstraeten, Maud; Krieg, Sarah; Korn, Patricia.

Cell Mol Life Sci ; 79(6): 288, 2022 May 10.

Artigo em Inglês | MEDLINE | ID: mdl-35536484

6.

ADP-ribosylation of RNA and DNA: from in vitro characterization to in vivo function.

Weixler, Lisa; Schäringer, Katja; Momoh, Jeffrey; Lüscher, Bernhard; Feijs, Karla L H; Zaja, Roko.

Nucleic Acids Res ; 49(7): 3634-3650, 2021 04 19.

Artigo em Inglês | MEDLINE | ID: mdl-33693930

7.

The mono-ADP-ribosyltransferase ARTD10 regulates the voltage-gated K⁺ channel Kv1.1 through protein kinase C delta.

Tian, Yuemin; Korn, Patricia; Tripathi, Priyanka; Komnig, Daniel; Wiemuth, Dominik; Nikouee, Azadeh; Classen, Arno; Bolm, Carsten; Falkenburger, Björn H; Lüscher, Bernhard; Gründer, Stefan.

BMC Biol ; 18(1): 143, 2020 10 15.

Artigo em Inglês | MEDLINE | ID: mdl-33059680

8.

ADP-Ribosylation, a Multifaceted Posttranslational Modification Involved in the Control of Cell Physiology in Health and Disease.

Lüscher, Bernhard; Bütepage, Mareike; Eckei, Laura; Krieg, Sarah; Verheugd, Patricia; Shilton, Brian H.

Chem Rev ; 118(3): 1092-1136, 2018 02 14.

Artigo em Inglês | MEDLINE | ID: mdl-29172462

9.

The Absence of DHHC3 Affects Primary and Latent Herpes Simplex Virus 1 Infection.

Wang, Shaohui; Mott, Kevin R; Cilluffo, Marianne; Kilpatrick, Casey L; Murakami, Shoko; Ljubimov, Alexander V; Kousoulas, Konstantin G; Awasthi, Sita; Luscher, Bernhard; Ghiasi, Homayon.

J Virol ; 92(4)2018 02 15.

Artigo em Inglês | MEDLINE | ID: mdl-29187538

10.

DHHC7 Palmitoylates Glucose Transporter 4 (Glut4) and Regulates Glut4 Membrane Translocation.

Du, Keyong; Murakami, Shoko; Sun, Yingmin; Kilpatrick, Casey L; Luscher, Bernhard.

J Biol Chem ; 292(7): 2979-2991, 2017 02 17.

Artigo em Inglês | MEDLINE | ID: mdl-28057756

11.

Binding of Herpes Simplex Virus 1 UL20 to GODZ (DHHC3) Affects Its Palmitoylation and Is Essential for Infectivity and Proper Targeting and Localization of UL20 and Glycoprotein K.

Wang, Shaohui; Mott, Kevin R; Wawrowsky, Kolja; Kousoulas, Konstantin G; Luscher, Bernhard; Ghiasi, Homayon.

J Virol ; 91(19)2017 10 01.

Artigo em Inglês | MEDLINE | ID: mdl-28724772

12.

Effects of a ceramide-containing water-in-oil ointment on skin barrier function and allergen penetration in an IL-31 treated 3D model of the disrupted skin barrier.

Huth, Sebastian; Schmitt, Laurenz; Marquardt, Yvonne; Heise, Ruth; Lüscher, Bernhard; Amann, Philipp M; Baron, Jens M.

Exp Dermatol ; 27(9): 1009-1014, 2018 09.

Artigo em Inglês | MEDLINE | ID: mdl-29851147

13.

Control of the Physical and Antimicrobial Skin Barrier by an IL-31-IL-1 Signaling Network.

Hänel, Kai H; Pfaff, Carolina M; Cornelissen, Christian; Amann, Philipp M; Marquardt, Yvonne; Czaja, Katharina; Kim, Arianna; Lüscher, Bernhard; Baron, Jens M.

J Immunol ; 196(8): 3233-44, 2016 Apr 15.

Artigo em Inglês | MEDLINE | ID: mdl-26944931

14.

Neuronal circuitry mechanism regulating adult quiescent neural stem-cell fate decision.

Song, Juan; Zhong, Chun; Bonaguidi, Michael A; Sun, Gerald J; Hsu, Derek; Gu, Yan; Meletis, Konstantinos; Huang, Z Josh; Ge, Shaoyu; Enikolopov, Grigori; Deisseroth, Karl; Luscher, Bernhard; Christian, Kimberly M; Ming, Guo-li; Song, Hongjun.

Nature ; 489(7414): 150-4, 2012 Sep 06.

Artigo em Inglês | MEDLINE | ID: mdl-22842902

15.

Structural prediction of the interaction of the tumor suppressor p27^KIP1 with cyclin A/CDK2 identifies a novel catalytically relevant determinant.

Li, Jinyu; Vervoorts, Jörg; Carloni, Paolo; Rossetti, Giulia; Lüscher, Bernhard.

BMC Bioinformatics ; 18(1): 15, 2017 Jan 05.

Artigo em Inglês | MEDLINE | ID: mdl-28056778

16.

Dissociation of Golgi-associated DHHC-type Zinc Finger Protein (GODZ)- and Sertoli Cell Gene with a Zinc Finger Domain-ß (SERZ-ß)-mediated Palmitoylation by Loss of Function Analyses in Knock-out Mice.

Kilpatrick, Casey L; Murakami, Shoko; Feng, Mengyang; Wu, Xia; Lal, Rachnanjali; Chen, Gong; Du, Keyong; Luscher, Bernhard.

J Biol Chem ; 291(53): 27371-27386, 2016 12 30.

Artigo em Inglês | MEDLINE | ID: mdl-27875292

17.

IκB kinaseα/ß control biliary homeostasis and hepatocarcinogenesis in mice by phosphorylating the cell-death mediator receptor-interacting protein kinase 1.

Koppe, Christiane; Verheugd, Patricia; Gautheron, Jérémie; Reisinger, Florian; Kreggenwinkel, Karina; Roderburg, Christoph; Quagliata, Luca; Terracciano, Luigi; Gassler, Nikolaus; Tolba, René H; Boege, Yannick; Weber, Achim; Karin, Michael; Luedde, Mark; Neumann, Ulf P; Weiskirchen, Ralf; Tacke, Frank; Vucur, Mihael; Trautwein, Christian; Lüscher, Bernhard; Preisinger, Christian; Heikenwalder, Mathias; Luedde, Tom.

Hepatology ; 64(4): 1217-31, 2016 10.

Artigo em Inglês | MEDLINE | ID: mdl-27396433

18.

Palmitoylation of gephyrin controls receptor clustering and plasticity of GABAergic synapses.

Dejanovic, Borislav; Semtner, Marcus; Ebert, Silvia; Lamkemeyer, Tobias; Neuser, Franziska; Lüscher, Bernhard; Meier, Jochen C; Schwarz, Guenter.

PLoS Biol ; 12(7): e1001908, 2014 Jul.

Artigo em Inglês | MEDLINE | ID: mdl-25025157

19.

Sulfoximines as ATR inhibitors: Analogs of VE-821.

Hendriks, Christine M M; Hartkamp, Jörg; Wiezorek, Stefan; Steinkamp, Anne-Dorothee; Rossetti, Giulia; Lüscher, Bernhard; Bolm, Carsten.

Bioorg Med Chem Lett ; 27(12): 2659-2662, 2017 06 15.

Artigo em Inglês | MEDLINE | ID: mdl-28479198

20.

Inhibition of SIRT2 suppresses hepatic fibrosis.

Arteaga, Maribel; Shang, Na; Ding, Xianzhong; Yong, Sherri; Cotler, Scott J; Denning, Mitchell F; Shimamura, Takashi; Breslin, Peter; Lüscher, Bernhard; Qiu, Wei.

Am J Physiol Gastrointest Liver Physiol ; 310(11): G1155-68, 2016 06 01.

Artigo em Inglês | MEDLINE | ID: mdl-27125275

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