Detalhe da pesquisa
1.
7-Deazaguanines in DNA: functional and structural elucidation of a DNA modification system.
Nucleic Acids Res
; 51(8): 3836-3854, 2023 05 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-36928176
2.
PlzA is a bifunctional c-di-GMP biosensor that promotes tick and mammalian host-adaptation of Borrelia burgdorferi.
PLoS Pathog
; 17(7): e1009725, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34265024
3.
Specificity in the biosynthesis of the universal tRNA nucleoside N6-threonylcarbamoyl adenosine (t6A)-TsaD is the gatekeeper.
RNA
; 26(9): 1094-1103, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32385138
4.
Evidence that immunization with TP0751, a bipartite Treponema pallidum lipoprotein with an intrinsically disordered region and lipocalin fold, fails to protect in the rabbit model of experimental syphilis.
PLoS Pathog
; 16(9): e1008871, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32936831
5.
Structural Modeling of the Treponema pallidum Outer Membrane Protein Repertoire: a Road Map for Deconvolution of Syphilis Pathogenesis and Development of a Syphilis Vaccine.
J Bacteriol
; 203(15): e0008221, 2021 07 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33972353
6.
Conformational communication mediates the reset step in t6A biosynthesis.
Nucleic Acids Res
; 47(12): 6551-6567, 2019 07 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31114923
7.
Structure and mechanism of a bacterial t6A biosynthesis system.
Nucleic Acids Res
; 46(3): 1395-1411, 2018 02 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-29309633
8.
Inhibitor potency varies widely among tumor-relevant human isocitrate dehydrogenase 1 mutants.
Biochem J
; 475(20): 3221-3238, 2018 10 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-30249606
9.
Mechanism and catalytic strategy of the prokaryotic-specific GTP cyclohydrolase-IB.
Biochem J
; 474(6): 1017-1039, 2017 03 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-28126741
10.
Bipartite Topology of Treponema pallidum Repeat Proteins C/D and I: OUTER MEMBRANE INSERTION, TRIMERIZATION, AND PORIN FUNCTION REQUIRE A C-TERMINAL ß-BARREL DOMAIN.
J Biol Chem
; 290(19): 12313-31, 2015 May 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-25805501
11.
Stage-specific global alterations in the transcriptomes of Lyme disease spirochetes during tick feeding and following mammalian host adaptation.
Mol Microbiol
; 95(3): 509-38, 2015 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-25425211
12.
A Homology Model Reveals Novel Structural Features and an Immunodominant Surface Loop/Opsonic Target in the Treponema pallidum BamA Ortholog TP_0326.
J Bacteriol
; 197(11): 1906-20, 2015 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-25825429
13.
Structural characterization and modeling of the Borrelia burgdorferi hybrid histidine kinase Hk1 periplasmic sensor: A system for sensing small molecules associated with tick feeding.
J Struct Biol
; 192(1): 48-58, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26321039
14.
Subconjunctival hemorrhage post hyaluronic acid filler for cheeks and tear trough deformity.
Dermatol Ther
; 33(6): e13902, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32588942
15.
Structural modeling and physicochemical characterization provide evidence that P66 forms a ß-barrel in the Borrelia burgdorferi outer membrane.
J Bacteriol
; 196(4): 859-72, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-24317399
16.
Rv3868 (EccA1), an essential component of the Mycobacterium tuberculosis ESX-1 secretion system, is thermostable.
Biochim Biophys Acta
; 1834(6): 1181-6, 2013 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-23415725
17.
The major outer sheath protein (Msp) of Treponema denticola has a bipartite domain architecture and exists as periplasmic and outer membrane-spanning conformers.
J Bacteriol
; 195(9): 2060-71, 2013 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-23457251
18.
TprC/D (Tp0117/131), a trimeric, pore-forming rare outer membrane protein of Treponema pallidum, has a bipartite domain structure.
J Bacteriol
; 194(9): 2321-33, 2012 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-22389487
19.
The transition from closed to open conformation of Treponema pallidum outer membrane-associated lipoprotein TP0453 involves membrane sensing and integration by two amphipathic helices.
J Biol Chem
; 286(48): 41656-41668, 2011 Dec 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-21965687
20.
TP0326, a Treponema pallidum ß-barrel assembly machinery A (BamA) orthologue and rare outer membrane protein.
Mol Microbiol
; 80(6): 1496-515, 2011 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-21488980