Detalhe da pesquisa
1.
Integration of the Transcriptome and Genome-Wide Landscape of BRD2 and BRD4 Binding Motifs Identifies Key Superenhancer Genes and Reveals the Mechanism of Bet Inhibitor Action in Rheumatoid Arthritis Synovial Fibroblasts.
J Immunol
; 206(2): 422-431, 2021 01 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33288543
2.
Bempegaldesleukin (BEMPEG; NKTR-214) efficacy as a single agent and in combination with checkpoint-inhibitor therapy in mouse models of osteosarcoma.
Int J Cancer
; 148(8): 1928-1937, 2021 04 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33152115
3.
Role of Vγ9vδ2 T lymphocytes in infectious diseases.
Front Immunol
; 13: 928441, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35924233
4.
BTN3A Targeting Vγ9Vδ2 T Cells Antimicrobial Activity Against Coxiella burnetii-Infected Cells.
Front Immunol
; 13: 915244, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35833118
5.
NKTR-255 is a polymer-conjugated IL-15 with unique mechanisms of action on T and natural killer cells.
J Clin Invest
; 131(19)2021 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34375310
6.
Discovery of the Bruton's Tyrosine Kinase Inhibitor Clinical Candidate TAK-020 (S)-5-(1-((1-Acryloylpyrrolidin-3-yl)oxy)isoquinolin-3-yl)-2,4-dihydro-3H-1,2,4-triazol-3-one, by Fragment-Based Drug Design.
J Med Chem
; 64(17): 12893-12902, 2021 09 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34448571
7.
NKTR-255, a novel polymer-conjugated rhIL-15 with potent antitumor efficacy.
J Immunother Cancer
; 9(5)2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-34001523
8.
Acquired and natural memory T cells join forces at the mucosal front line.
Nat Rev Immunol
; 4(4): 290-300, 2004 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-15057787
9.
PD-L1- and calcitriol-dependent liposomal antigen-specific regulation of systemic inflammatory autoimmune disease.
JCI Insight
; 4(18)2019 09 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-31487265
10.
Immune checkpoint inhibitor PD-1 pathway is down-regulated in synovium at various stages of rheumatoid arthritis disease progression.
PLoS One
; 13(2): e0192704, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29489833
11.
Integrative analysis reveals CD38 as a therapeutic target for plasma cell-rich pre-disease and established rheumatoid arthritis and systemic lupus erythematosus.
Arthritis Res Ther
; 20(1): 85, 2018 05 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29720240
12.
Correction to "Discovery of the Bruton's Tyrosine Kinase Inhibitor Clinical Candidate TAK-020 (S)-5-(1-((1-Acryloylpyrrolidin-3-yl)oxy)isoquinolin-3-yl)-2,4-dihydro-3H-1,2,4-triazol-3-one, by Fragment-Based Drug Design".
J Med Chem
; 64(21): 16318, 2021 Nov 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34708652
13.
Limited clonality in autoimmunity: drivers and regulators.
Autoimmun Rev
; 3(7-8): 524-9, 2004 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-15546801
14.
Seven surprises in the TCR-centred regulation of immune responsiveness in an autoimmune system.
Novartis Found Symp
; 252: 165-71; discussion 171-6, 203-10, 2003.
Artigo
em Inglês
| MEDLINE | ID: mdl-14609218
15.
Immunodominance in the TCR repertoire of a [corrected] TCR peptide-specific CD4+ Treg population that controls experimental autoimmune encephalomyelitis.
J Immunol
; 180(7): 4577-85, 2008 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-18354180
16.
Regulatory T cells control autoimmunity in vivo by inducing apoptotic depletion of activated pathogenic lymphocytes.
J Immunol
; 170(6): 2985-92, 2003 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-12626551
17.
CD8alphaalpha-mediated survival and differentiation of CD8 memory T cell precursors.
Science
; 304(5670): 590-3, 2004 Apr 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-15105501