Detalhe da pesquisa
1.
Indoline CD4-mimetic compounds mediate potent and broad HIV-1 inhibition and sensitization to antibody-dependent cellular cytotoxicity.
Proc Natl Acad Sci U S A
; 120(13): e2222073120, 2023 03 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-36961924
2.
V3 tip determinants of susceptibility to inhibition by CD4-mimetic compounds in natural clade A human immunodeficiency virus (HIV-1) envelope glycoproteins.
J Virol
; 97(11): e0117123, 2023 Nov 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-37888980
3.
Gaza's broken health-care system is compounding the risk of disease.
Nature
; 623(7985): 32, 2023 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-37907635
4.
Characterization of Human Immunodeficiency Virus (HIV-1) Envelope Glycoprotein Variants Selected for Resistance to a CD4-Mimetic Compound.
J Virol
; 96(17): e0063622, 2022 09 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-35980207
5.
Gp41-targeted antibodies restore infectivity of a fusion-deficient HIV-1 envelope glycoprotein.
PLoS Pathog
; 16(5): e1008577, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32392227
6.
Long-Acting BMS-378806 Analogues Stabilize the State-1 Conformation of the Human Immunodeficiency Virus Type 1 Envelope Glycoproteins.
J Virol
; 94(10)2020 05 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32161177
7.
Strain-Dependent Activation and Inhibition of Human Immunodeficiency Virus Entry by a Specific PF-68742 Stereoisomer.
J Virol
; 93(21)2019 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31391272
8.
Comparison of Uncleaved and Mature Human Immunodeficiency Virus Membrane Envelope Glycoprotein Trimers.
J Virol
; 92(12)2018 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29618643
9.
Crystal structures of trimeric HIV envelope with entry inhibitors BMS-378806 and BMS-626529.
Nat Chem Biol
; 13(10): 1115-1122, 2017 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-28825711
10.
A Small-Molecule CD4-Mimetic Compound Protects Bone Marrow-Liver-Thymus Humanized Mice From HIV-1 Infection.
J Infect Dis
; 218(3): 471-475, 2018 07 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29617845
11.
Activation and Inactivation of Primary Human Immunodeficiency Virus Envelope Glycoprotein Trimers by CD4-Mimetic Compounds.
J Virol
; 91(3)2017 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27881646
12.
Induction of a Tier-1-Like Phenotype in Diverse Tier-2 Isolates by Agents That Guide HIV-1 Env to Perturbation-Sensitive, Nonnative States.
J Virol
; 91(15)2017 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28490588
13.
Residues in the gp41 Ectodomain Regulate HIV-1 Envelope Glycoprotein Conformational Transitions Induced by gp120-Directed Inhibitors.
J Virol
; 91(5)2017 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28003492
14.
CD4 mimetics sensitize HIV-1-infected cells to ADCC.
Proc Natl Acad Sci U S A
; 112(20): E2687-94, 2015 May 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-25941367
15.
Antibodies Elicited by Multiple Envelope Glycoprotein Immunogens in Primates Neutralize Primary Human Immunodeficiency Viruses (HIV-1) Sensitized by CD4-Mimetic Compounds.
J Virol
; 90(10): 5031-5046, 2016 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26962221
16.
Evaluation of the contribution of the transmembrane region to the ectodomain conformation of the human immunodeficiency virus (HIV-1) envelope glycoprotein.
Virol J
; 14(1): 33, 2017 02 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-28209172
17.
CD4-mimetic small molecules sensitize human immunodeficiency virus to vaccine-elicited antibodies.
J Virol
; 88(12): 6542-55, 2014 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-24696475
18.
Structure-based design, synthesis and validation of CD4-mimetic small molecule inhibitors of HIV-1 entry: conversion of a viral entry agonist to an antagonist.
Acc Chem Res
; 47(4): 1228-37, 2014 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24502450
19.
Discovery and optimization of novel small-molecule HIV-1 entry inhibitors using field-based virtual screening and bioisosteric replacement.
Bioorg Med Chem Lett
; 24(23): 5439-45, 2014 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25454268
20.
AIDS epidemic: Iran needs global support to fight HIV.
Nature
; 494(7437): 314, 2013 Feb 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-23426315