Detalhe da pesquisa
1.
Persistent Hepatitis E virus infection across England and Wales 2009-2017: Demography, virology and outcomes.
J Viral Hepat
; 28(2): 420-430, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33073452
2.
Evaluation of clinical and genetic factors in the population pharmacokinetics of carbamazepine.
Br J Clin Pharmacol
; 87(6): 2572-2588, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33217013
3.
Definition of Haptens Derived from Sulfamethoxazole: In Vitro and in Vivo.
Chem Res Toxicol
; 32(10): 2095-2106, 2019 10 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-31468968
4.
Characterisation of the NRF2 transcriptional network and its response to chemical insult in primary human hepatocytes: implications for prediction of drug-induced liver injury.
Arch Toxicol
; 93(2): 385-399, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30426165
5.
Characterization of the Specificity, Functionality, and Durability of Host T-Cell Responses Against the Full-Length Hepatitis E Virus.
Hepatology
; 64(6): 1934-1950, 2016 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27631819
6.
Mass Spectrometric Characterization of Circulating Covalent Protein Adducts Derived from Epoxide Metabolites of Carbamazepine in Patients.
Chem Res Toxicol
; 30(7): 1419-1435, 2017 07 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-28562019
7.
Dapsone and Nitroso Dapsone Activation of NaiÌve T-Cells from Healthy Donors.
Chem Res Toxicol
; 30(12): 2174-2186, 2017 12 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-29045131
8.
Auto-oxidation of Isoniazid Leads to Isonicotinic-Lysine Adducts on Human Serum Albumin.
Chem Res Toxicol
; 28(1): 51-8, 2015 Jan 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-25489718
9.
Characterization of Peroxidases Expressed in Human Antigen Presenting Cells and Analysis of the Covalent Binding of Nitroso Sulfamethoxazole to Myeloperoxidase.
Chem Res Toxicol
; 28(1): 144-54, 2015 Jan 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-25531135
10.
Mass spectrometric characterization of circulating covalent protein adducts derived from a drug acyl glucuronide metabolite: multiple albumin adductions in diclofenac patients.
J Pharmacol Exp Ther
; 350(2): 387-402, 2014 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-24902585
11.
Abacavir forms novel cross-linking abacavir protein adducts in patients.
Chem Res Toxicol
; 27(4): 524-35, 2014 Apr 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-24571427
12.
Oxidative bioactivation of abacavir in subcellular fractions of human antigen presenting cells.
Chem Res Toxicol
; 26(7): 1064-72, 2013 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23697900
13.
Convenient syntheses of halo-dibenz[b,f]azepines and carbamazepine analogues via N-arylindoles.
Org Biomol Chem
; 11(48): 8426-34, 2013 Dec 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-24193242
14.
The role of heme and the mitochondrion in the chemical and molecular mechanisms of mammalian cell death induced by the artemisinin antimalarials.
J Biol Chem
; 286(2): 987-96, 2011 Jan 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-21059641
15.
Direct evidence for the formation of diastereoisomeric benzylpenicilloyl haptens from benzylpenicillin and benzylpenicillenic acid in patients.
J Pharmacol Exp Ther
; 338(3): 841-9, 2011 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-21680886
16.
Quantifying the metabolic activation of nevirapine in patients by integrated applications of NMR and mass spectrometries.
Drug Metab Dispos
; 38(1): 122-32, 2010 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-19797610
17.
Metabolic and chemical origins of cross-reactive immunological reactions to arylamine benzenesulfonamides: T-cell responses to hydroxylamine and nitroso derivatives.
Chem Res Toxicol
; 23(1): 184-92, 2010 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-19954178
18.
Acyl glucuronides: the good, the bad and the ugly.
Biopharm Drug Dispos
; 31(7): 367-95, 2010 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-20830700
19.
Mortality and the risk of malignancy in autoimmune liver diseases: a population-based study in Canterbury, New Zealand.
Hepatology
; 57(4): 1677, 2013 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-22815246
20.
A mechanistic investigation into the irreversible protein binding and antigenicity of p-phenylenediamine.
Chem Res Toxicol
; 22(6): 1172-80, 2009 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-19469519