Motivational enhancement therapy with and without cognitive behavior therapy to treat type 1 diabetes: a randomized trial.

BACKGROUND: Although psychological issues can interfere with diabetes care, the effectiveness of psychological treatments in improving diabetes outcomes is uncertain. OBJECTIVE: To determine whether motivational enhancement therapy with or without cognitive behavior therapy improves glycemic control in type 1 diabetes compared with usual care. DESIGN: Randomized, controlled trial. SETTING: 8 diabetes centers in London and Manchester, United Kingdom. PATIENTS: 344 adults with type 1 diabetes for longer than 2 years, with hemoglobin A(1c) levels of 8.2% to 15%, and without complications or severe comorbid disease. INTERVENTION: Nurse-delivered motivational enhancement therapy (4 sessions over 2 months), motivational enhancement therapy plus cognitive behavior therapy (12 sessions over 6 months), or usual care. MEASUREMENTS: 12-month change in hemoglobin A(1c) levels (primary outcome), hypoglycemic events, depression, quality of life, fear of hypoglycemia, diabetes self-care activities, and body mass index (secondary outcomes). RESULTS: In an analysis including all randomly assigned patients, the 12-month change in hemoglobin A(1c) levels compared with usual care was -0.46% (95% CI, -0.81% to -0.11%) in the motivational enhancement therapy plus cognitive behavior therapy group and -0.19% (CI, -0.53% to 0.16%) in the motivational enhancement therapy group alone. There was no evidence of treatment effects on secondary outcomes. LIMITATIONS: Of 1659 screened patients, only 507 were eligible and 344 participated. Data on the primary outcome were unavailable for 11.3% of the participants. Study design did not permit distinction of the additive effect of cognitive behavior therapy plus motivational enhancement therapy from the effect of greater intensity and duration of the combined intervention compared with the motivational enhancement therapy alone. CONCLUSION: Nurse-delivered motivational enhancement therapy and cognitive behavior therapy is feasible for adults with poorly controlled type 1 diabetes. Combined therapy results in modest 12-month improvement in hemoglobin A(1c) levels compared with usual care, but motivational enhancement therapy alone does not.

The purpose of attributing cause: beliefs about the causes of myocardial infarction.

Patients' beliefs concerning the causes of their illnesses are core to a number of theoretical models of illness behaviour. The current study explored the themes that emerged from patients' accounts of the causes of their first myocardial infarctions (MIs). Semi-structured interviews were conducted with 12 patients within a week of their MI, at a UK district hospital. Transcripts were analysed using interpretative phenomenological analysis. Three researchers noted themes that emerged from each interview, then common themes were selected and refined on the basis of an aggregation of interviews. Three dominant themes emerged: (1) single versus multiple causation, (2) causes as triggers versus underlying dispositions, and (3) the potentially conflicting motives of avoiding blame whilst at the same time, seeking control. Whilst many participants had complex ideas concerning what caused their MI, and could often name several causes, they tended to emphasise the importance of a single cause, which often related to their symptoms. Further, several participants interpreted "cause" in terms of an acute trigger of MI, rather than as a chronic causal factor. Participants were apparently attempting to answer the question about why they had an MI now, leading to talk about single causes that trigger MI. By contrast, much previous research has been concerned with patients' knowledge of "risk factors", considering the production of only a few causes to reflect ignorance. A key process in participants attributing cause appeared to be attempting to avoid blaming themselves or others for their MI, whilst simultaneously seeking to assert control over future recurrence. Analysis of the functions and purposes of causal attribution suggests that patients' focus on blame and control may be both emotionally and behaviourally adaptive, if not necessarily epidemiologically precise. These findings suggest that interventions to change causal attributions may be misguided, and may even be harmful.

Nurse-led psychological interventions to improve diabetes control: assessing competencies.

OBJECTIVE: To assess whether medical nurses can deliver motivational enhancement therapy (MET) and cognitive behavioural therapy (CBT) to a competent level and whether treatment fidelity is maintained. METHODS: Training consisted of classroom teaching, written materials, a training caseload, and audio-visual feedback. We used the Motivational Interviewing Treatment Integrity (MITI), the Revised 12-item Cognitive Therapy Scale (CTS-R), and components of the Motivational Interviewing Skill Code (MISC) to assess competency and treatment fidelity. Two independent clinical psychologists who were blind to the allocation rated a random selection of 40 sessions. RESULTS: Six nurses were trained in both interventions. For the MET the mean (SD) scores for empathy and spirit on the MITI scale were 5.1 (0.7) and 4.6 (1.0) respectively and for CBT the total mean (SD) CTS-R score was 52.1 (7.5), which was acceptable competency in both treatments. The two interventions were distinguishable. CONCLUSION: Results suggest that nurses can be trained to deliver diabetes-specific MET and CBT competently and maintain treatment fidelity. PRACTICE IMPLICATIONS: Findings of this study provide preliminary evidence to suggest that nurse-led psychological interventions could be incorporated into the traditional diabetes setting.

The psychological costs of inadequate cervical smear test results: three-month follow-up.

We have previously shown that upon receipt of inadequate cervical smear test results, women have elevated levels of state anxiety and concern about their test results, similar to those of women receiving abnormal smear test results. The current paper reports data on the psychological impact three months after receiving an inadequate smear test result. Two groups of women who initially received a normal test result (n=184) or either a first or non-consecutive inadequate smear test result (n=140) responded. Women with initially received inadequate smear test results no longer had higher state anxiety than women who received normal test results. However, women who initially received inadequate smear test results were still more concerned about their test results and less satisfied with the information they had received about these initial test results, even after receiving normal results from repeat cervical smear tests. Concern was strongly predicted by dissatisfaction with information provided about inadequate smear test results. These results underscore the need to improve communication about inadequate cervical smear test results.

Psychological impact of human papillomavirus testing in women with borderline or mildly dyskaryotic cervical smear test results: cross sectional questionnaire study.

OBJECTIVE: To describe the psychological impact on women of being tested for human papillomavirus (HPV) when smear test results are borderline or mildly dyskaryotic. DESIGN: Cross sectional questionnaire study. SETTING: Two centres participating in an English pilot study of HPV testing in women with borderline or mildly dyskaryotic smear test results. PARTICIPANTS: Women receiving borderline or mildly dyskaryotic smear test results tested for HPV and found to be HPV positive (n = 536) or HPV negative (n = 331); and women not tested for HPV with borderline or mildly dyskaryotic smear results (n = 143) or normal smear results (n = 366). MAIN OUTCOME MEASURES: State anxiety, distress, and concern about test result, assessed within four weeks of receipt of results. RESULTS: Women with borderline or mildly dyskaryotic smear results who were HPV positive were more anxious, distressed, and concerned than the other three groups. Three variables independently predicted anxiety in HPV positive women: younger age (beta = -0.11, P = 0.03), higher perceived risk of cervical cancer (beta = 0.17, P < 0.001), and reporting that they did not understand the meaning of test results (beta = 0.17, P = 0.001). Testing HPV negative was not reassuring: among women with abnormal smear test results, those who were HPV negative were no less anxious than those who were not tested for HPV. CONCLUSIONS: Informing women more effectively about the meaning of borderline or mildly dyskaryotic smear test results and HPV status, in particular about the absolute risks of cervical cancer and the prevalence of HPV infection, may avoid some anxiety for those who are HPV positive while achieving some reassurance for those who test HPV negative.