Assuntos
Granuloma/patologia , Glomérulos Renais/patologia , Nefrite Intersticial/patologia , Proteinúria/patologia , Sarcoidose/patologia , Adulto , Biópsia com Agulha de Grande Calibre , Glucocorticoides/uso terapêutico , Granuloma/tratamento farmacológico , Humanos , Glomérulos Renais/efeitos dos fármacos , Masculino , Nefrite Intersticial/tratamento farmacológico , Prednisona/uso terapêutico , Proteinúria/tratamento farmacológico , Sarcoidose/tratamento farmacológico , Resultado do TratamentoRESUMO
BACKGROUND: Waldenström's macroglobulinemia is a low-grade B-cell lymphoma characterized by monoclonal synthesis and secretion of IgM antibodies [3]. The classic symptoms of WM result from blood hyperviscosity. Neurologic symptoms, such as fatigue, dizziness, and blurred vision, are common. The metastatic spread to the CNS, which rarely has been reported, can occur either diffusely or in the form of a mass lesion. CASE DESCRIPTION: We present the case of a 73-year-old woman with intracerebral large B-cell lymphoma and concurrent WM. CONCLUSION: This case illustrates the importance of histopathologic diagnosis by brain biopsy despite an existing diagnosis of systemic neoplasm.
Assuntos
Neoplasias Encefálicas/complicações , Neoplasias Encefálicas/patologia , Linfoma de Células B/complicações , Linfoma de Células B/patologia , Macroglobulinemia de Waldenstrom/complicações , Macroglobulinemia de Waldenstrom/patologia , Idoso , Neoplasias Encefálicas/terapia , Feminino , Humanos , Linfoma de Células B/terapia , Macroglobulinemia de Waldenstrom/terapiaRESUMO
Head and neck sarcomas are rare but are associated with significant morbidity/mortality and management difficulties. These tumors are best managed in a multidisciplinary setting. Open or core biopsy is essential for histologic diagnosis and grading. Complete surgical tumor resection with negative margins at the first attempt is the best chance for potential cure. In most patients, except those with small resectable low-grade lesions, adjuvant radiotherapy and chemotherapy are added to maximize local control with variable results. Resection margins effect on recurrence rate and treatment modalities in selective types of head and neck sarcomas are discussed in this article.
Assuntos
Neoplasias de Cabeça e Pescoço/patologia , Margens de Excisão , Sarcoma/patologia , Quimioterapia Adjuvante , Neoplasias de Cabeça e Pescoço/cirurgia , Humanos , Prognóstico , Radioterapia Adjuvante , Sarcoma/cirurgiaRESUMO
Eosinophilic polymyositis (EPM) is part of a rare disorder, eosinophilic myopathies (EM), which is a form of polymyositis characterized by the presence of eosinophils in muscle biopsy sections and occasionally blood eosinophilia. Herein, we are presenting an interesting case of eosinophilic polymyositis presenting with muscle pain with no other organ systems involved.