Detalhe da pesquisa
1.
Pathophysiology and pathogenic mechanisms of pulmonary hypertension: role of membrane receptors, ion channels, and Ca2+ signaling.
Physiol Rev
; 103(3): 1827-1897, 2023 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36422993
2.
Mechanosensitive cation currents through TRPC6 and Piezo1 channels in human pulmonary arterial endothelial cells.
Am J Physiol Cell Physiol
; 323(4): C959-C973, 2022 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35968892
3.
Mechanosensitive channel Piezo1 is required for pulmonary artery smooth muscle cell proliferation.
Am J Physiol Lung Cell Mol Physiol
; 322(5): L737-L760, 2022 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35318857
4.
Endothelial upregulation of mechanosensitive channel Piezo1 in pulmonary hypertension.
Am J Physiol Cell Physiol
; 321(6): C1010-C1027, 2021 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34669509
5.
TRPC6, a therapeutic target for pulmonary hypertension.
Am J Physiol Lung Cell Mol Physiol
; 321(6): L1161-L1182, 2021 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34704831
6.
mTOR Signaling in Pulmonary Vascular Disease: Pathogenic Role and Therapeutic Target.
Int J Mol Sci
; 22(4)2021 Feb 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-33670032
7.
Notch enhances Ca2+ entry by activating calcium-sensing receptors and inhibiting voltage-gated K+ channels.
Am J Physiol Cell Physiol
; 318(5): C954-C968, 2020 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32186932
8.
MicroRNA-mediated downregulation of K+ channels in pulmonary arterial hypertension.
Am J Physiol Lung Cell Mol Physiol
; 318(1): L10-L26, 2020 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31553627
9.
Pulmonary vascular dysfunction in metabolic syndrome.
J Physiol
; 597(4): 1121-1141, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30125956
10.
Divergent changes of p53 in pulmonary arterial endothelial and smooth muscle cells involved in the development of pulmonary hypertension.
Am J Physiol Lung Cell Mol Physiol
; 316(1): L216-L228, 2019 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30358436
11.
Akt2 (Protein Kinase B Beta) Stabilizes ATP7A, a Copper Transporter for Extracellular Superoxide Dismutase, in Vascular Smooth Muscle: Novel Mechanism to Limit Endothelial Dysfunction in Type 2 Diabetes Mellitus.
Arterioscler Thromb Vasc Biol
; 38(3): 529-541, 2018 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29301787
12.
Overexpression of hexokinase 2 reduces mitochondrial calcium overload in coronary endothelial cells of type 2 diabetic mice.
Am J Physiol Cell Physiol
; 314(6): C732-C740, 2018 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29513568
13.
Hypoxia selectively upregulates cation channels and increases cytosolic [Ca2+] in pulmonary, but not coronary, arterial smooth muscle cells.
Am J Physiol Cell Physiol
; 314(4): C504-C517, 2018 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29351410
14.
Endothelial HIF-2α contributes to severe pulmonary hypertension due to endothelial-to-mesenchymal transition.
Am J Physiol Lung Cell Mol Physiol
; 314(2): L256-L275, 2018 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29074488
15.
Mitochondrial connexin40 regulates mitochondrial calcium uptake in coronary endothelial cells.
Am J Physiol Cell Physiol
; 312(4): C398-C406, 2017 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28122731
16.
Capsaicin-induced Ca2+ signaling is enhanced via upregulated TRPV1 channels in pulmonary artery smooth muscle cells from patients with idiopathic PAH.
Am J Physiol Lung Cell Mol Physiol
; 312(3): L309-L325, 2017 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27979859
17.
ATP promotes cell survival via regulation of cytosolic [Ca2+] and Bcl-2/Bax ratio in lung cancer cells.
Am J Physiol Cell Physiol
; 310(2): C99-114, 2016 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26491047
18.
Pathogenic role of calcium-sensing receptors in the development and progression of pulmonary hypertension.
Am J Physiol Lung Cell Mol Physiol
; 310(9): L846-59, 2016 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26968768
19.
Notch Activation of Ca(2+) Signaling in the Development of Hypoxic Pulmonary Vasoconstriction and Pulmonary Hypertension.
Am J Respir Cell Mol Biol
; 53(3): 355-67, 2015 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-25569851
20.
O-GlcNAcase overexpression reverses coronary endothelial cell dysfunction in type 1 diabetic mice.
Am J Physiol Cell Physiol
; 309(9): C593-9, 2015 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26269457