Pesquisa | Portal de Pesquisa da BVS Enfermagem

1.

Systemwide disassembly and assembly of SCF ubiquitin ligase complexes.

Baek, Kheewoong; Scott, Daniel C; Henneberg, Lukas T; King, Moeko T; Mann, Matthias; Schulman, Brenda A.

Cell ; 186(9): 1895-1911.e21, 2023 04 27.

Artigo em Inglês | MEDLINE | ID: mdl-37028429

2.

Spatial proteomics in three-dimensional intact specimens.

Bhatia, Harsharan Singh; Brunner, Andreas-David; Öztürk, Furkan; Kapoor, Saketh; Rong, Zhouyi; Mai, Hongcheng; Thielert, Marvin; Ali, Mayar; Al-Maskari, Rami; Paetzold, Johannes Christian; Kofler, Florian; Todorov, Mihail Ivilinov; Molbay, Muge; Kolabas, Zeynep Ilgin; Negwer, Moritz; Hoeher, Luciano; Steinke, Hanno; Dima, Alina; Gupta, Basavdatta; Kaltenecker, Doris; Caliskan, Özüm Sehnaz; Brandt, Daniel; Krahmer, Natalie; Müller, Stephan; Lichtenthaler, Stefan Frieder; Hellal, Farida; Bechmann, Ingo; Menze, Bjoern; Theis, Fabian; Mann, Matthias; Ertürk, Ali.

Cell ; 185(26): 5040-5058.e19, 2022 12 22.

Artigo em Inglês | MEDLINE | ID: mdl-36563667

3.

SnapShot: Clinical proteomics.

Zhu, Yi; Aebersold, Ruedi; Mann, Matthias; Guo, Tiannan.

Cell ; 184(18): 4840-4840.e1, 2021 09 02.

Artigo em Inglês | MEDLINE | ID: mdl-34478659

4.

The CMG Helicase Bypasses DNA-Protein Cross-Links to Facilitate Their Repair.

Sparks, Justin L; Chistol, Gheorghe; Gao, Alan O; Räschle, Markus; Larsen, Nicolai B; Mann, Matthias; Duxin, Julien P; Walter, Johannes C.

Cell ; 176(1-2): 167-181.e21, 2019 01 10.

Artigo em Inglês | MEDLINE | ID: mdl-30595447

5.

The tumor suppressor kinase DAPK3 drives tumor-intrinsic immunity through the STING-IFN-ß pathway.

Takahashi, Mariko; Lio, Chan-Wang J; Campeau, Anaamika; Steger, Martin; Ay, Ferhat; Mann, Matthias; Gonzalez, David J; Jain, Mohit; Sharma, Sonia.

Nat Immunol ; 22(4): 485-496, 2021 04.

Artigo em Inglês | MEDLINE | ID: mdl-33767426

6.

Systemwide disassembly and assembly of SCF ubiquitin ligase complexes.

Baek, Kheewoong; Scott, Daniel C; Henneberg, Lukas T; King, Moeko T; Mann, Matthias; Schulman, Brenda A.

Cell ; 186(11): 2492, 2023 May 25.

Artigo em Inglês | MEDLINE | ID: mdl-37236156

7.

Multi-level Proteomics Identifies CT45 as a Chemosensitivity Mediator and Immunotherapy Target in Ovarian Cancer.

Coscia, Fabian; Lengyel, Ernst; Duraiswamy, Jaikumar; Ashcroft, Bradley; Bassani-Sternberg, Michal; Wierer, Michael; Johnson, Alyssa; Wroblewski, Kristen; Montag, Anthony; Yamada, S Diane; López-Méndez, Blanca; Nilsson, Jakob; Mund, Andreas; Mann, Matthias; Curtis, Marion.

Cell ; 175(1): 159-170.e16, 2018 09 20.

Artigo em Inglês | MEDLINE | ID: mdl-30241606

8.

Dynamics in protein translation sustaining T cell preparedness.

Wolf, Tobias; Jin, Wenjie; Zoppi, Giada; Vogel, Ian A; Akhmedov, Murodzhon; Bleck, Christopher K E; Beltraminelli, Tim; Rieckmann, Jan C; Ramirez, Neftali J; Benevento, Marco; Notarbartolo, Samuele; Bumann, Dirk; Meissner, Felix; Grimbacher, Bodo; Mann, Matthias; Lanzavecchia, Antonio; Sallusto, Federica; Kwee, Ivo; Geiger, Roger.

Nat Immunol ; 21(8): 927-937, 2020 08.

Artigo em Inglês | MEDLINE | ID: mdl-32632289

9.

Non-canonical substrate recognition by the human WDR26-CTLH E3 ligase regulates prodrug metabolism.

Gottemukkala, Karthik V; Chrustowicz, Jakub; Sherpa, Dawafuti; Sepic, Sara; Vu, Duc Tung; Karayel, Özge; Papadopoulou, Eleftheria C; Gross, Annette; Schorpp, Kenji; von Gronau, Susanne; Hadian, Kamyar; Murray, Peter J; Mann, Matthias; Schulman, Brenda A; Alpi, Arno F.

Mol Cell ; 84(10): 1948-1963.e11, 2024 May 16.

Artigo em Inglês | MEDLINE | ID: mdl-38759627

10.

Multisite phosphorylation dictates selective E2-E3 pairing as revealed by Ubc8/UBE2H-GID/CTLH assemblies.

Chrustowicz, Jakub; Sherpa, Dawafuti; Li, Jerry; Langlois, Christine R; Papadopoulou, Eleftheria C; Vu, D Tung; Hehl, Laura A; Karayel, Özge; Beier, Viola; von Gronau, Susanne; Müller, Judith; Prabu, J Rajan; Mann, Matthias; Kleiger, Gary; Alpi, Arno F; Schulman, Brenda A.

Mol Cell ; 84(2): 293-308.e14, 2024 Jan 18.

Artigo em Inglês | MEDLINE | ID: mdl-38113892

11.

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.

Hubel, Philipp; Urban, Christian; Bergant, Valter; Schneider, William M; Knauer, Barbara; Stukalov, Alexey; Scaturro, Pietro; Mann, Angelika; Brunotte, Linda; Hoffmann, Heinrich H; Schoggins, John W; Schwemmle, Martin; Mann, Matthias; Rice, Charles M; Pichlmair, Andreas.

Nat Immunol ; 20(4): 493-502, 2019 04.

Artigo em Inglês | MEDLINE | ID: mdl-30833792

12.

IKKß primes inflammasome formation by recruiting NLRP3 to the trans-Golgi network.

Schmacke, Niklas A; O'Duill, Fionan; Gaidt, Moritz M; Szymanska, Inga; Kamper, Julia M; Schmid-Burgk, Jonathan L; Mädler, Sophia C; Mackens-Kiani, Timur; Kozaki, Tatsuya; Chauhan, Dhruv; Nagl, Dennis; Stafford, Che A; Harz, Hartmann; Fröhlich, Adrian L; Pinci, Francesca; Ginhoux, Florent; Beckmann, Roland; Mann, Matthias; Leonhardt, Heinrich; Hornung, Veit.

Immunity ; 55(12): 2271-2284.e7, 2022 12 13.

Artigo em Inglês | MEDLINE | ID: mdl-36384135

13.

L-Arginine Modulates T Cell Metabolism and Enhances Survival and Anti-tumor Activity.

Geiger, Roger; Rieckmann, Jan C; Wolf, Tobias; Basso, Camilla; Feng, Yuehan; Fuhrer, Tobias; Kogadeeva, Maria; Picotti, Paola; Meissner, Felix; Mann, Matthias; Zamboni, Nicola; Sallusto, Federica; Lanzavecchia, Antonio.

Cell ; 167(3): 829-842.e13, 2016 Oct 20.

Artigo em Inglês | MEDLINE | ID: mdl-27745970

14.

A human interactome in three quantitative dimensions organized by stoichiometries and abundances.

Hein, Marco Y; Hubner, Nina C; Poser, Ina; Cox, Jürgen; Nagaraj, Nagarjuna; Toyoda, Yusuke; Gak, Igor A; Weisswange, Ina; Mansfeld, Jörg; Buchholz, Frank; Hyman, Anthony A; Mann, Matthias.

Cell ; 163(3): 712-23, 2015 Oct 22.

Artigo em Inglês | MEDLINE | ID: mdl-26496610

15.

Widespread Proteome Remodeling and Aggregation in Aging C. elegans.

Walther, Dirk M; Kasturi, Prasad; Zheng, Min; Pinkert, Stefan; Vecchi, Giulia; Ciryam, Prajwal; Morimoto, Richard I; Dobson, Christopher M; Vendruscolo, Michele; Mann, Matthias; Hartl, F Ulrich.

Cell ; 161(4): 919-32, 2015 May 07.

Artigo em Inglês | MEDLINE | ID: mdl-25957690

16.

Unbiased spatial proteomics with single-cell resolution in tissues.

Mund, Andreas; Brunner, Andreas-David; Mann, Matthias.

Mol Cell ; 82(12): 2335-2349, 2022 06 16.

Artigo em Inglês | MEDLINE | ID: mdl-35714588

17.

Social network architecture of human immune cells unveiled by quantitative proteomics.

Rieckmann, Jan C; Geiger, Roger; Hornburg, Daniel; Wolf, Tobias; Kveler, Ksenya; Jarrossay, David; Sallusto, Federica; Shen-Orr, Shai S; Lanzavecchia, Antonio; Mann, Matthias; Meissner, Felix.

Nat Immunol ; 18(5): 583-593, 2017 05.

Artigo em Inglês | MEDLINE | ID: mdl-28263321

18.

The social and structural architecture of the yeast protein interactome.

Michaelis, André C; Brunner, Andreas-David; Zwiebel, Maximilian; Meier, Florian; Strauss, Maximilian T; Bludau, Isabell; Mann, Matthias.

Nature ; 624(7990): 192-200, 2023 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-37968396

19.

Profiling the human intestinal environment under physiological conditions.

Shalon, Dari; Culver, Rebecca Neal; Grembi, Jessica A; Folz, Jacob; Treit, Peter V; Shi, Handuo; Rosenberger, Florian A; Dethlefsen, Les; Meng, Xiandong; Yaffe, Eitan; Aranda-Díaz, Andrés; Geyer, Philipp E; Mueller-Reif, Johannes B; Spencer, Sean; Patterson, Andrew D; Triadafilopoulos, George; Holmes, Susan P; Mann, Matthias; Fiehn, Oliver; Relman, David A; Huang, Kerwyn Casey.

Nature ; 617(7961): 581-591, 2023 May.

Artigo em Inglês | MEDLINE | ID: mdl-37165188

20.

GID E3 ligase supramolecular chelate assembly configures multipronged ubiquitin targeting of an oligomeric metabolic enzyme.

Sherpa, Dawafuti; Chrustowicz, Jakub; Qiao, Shuai; Langlois, Christine R; Hehl, Laura A; Gottemukkala, Karthik Varma; Hansen, Fynn M; Karayel, Ozge; von Gronau, Susanne; Prabu, J Rajan; Mann, Matthias; Alpi, Arno F; Schulman, Brenda A.

Mol Cell ; 81(11): 2445-2459.e13, 2021 06 03.

Artigo em Inglês | MEDLINE | ID: mdl-33905682

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Systemwide disassembly and assembly of SCF ubiquitin ligase complexes.

Spatial proteomics in three-dimensional intact specimens.

SnapShot: Clinical proteomics.

The CMG Helicase Bypasses DNA-Protein Cross-Links to Facilitate Their Repair.

The tumor suppressor kinase DAPK3 drives tumor-intrinsic immunity through the STING-IFN-ß pathway.

Systemwide disassembly and assembly of SCF ubiquitin ligase complexes.

Multi-level Proteomics Identifies CT45 as a Chemosensitivity Mediator and Immunotherapy Target in Ovarian Cancer.

Dynamics in protein translation sustaining T cell preparedness.

Non-canonical substrate recognition by the human WDR26-CTLH E3 ligase regulates prodrug metabolism.

Multisite phosphorylation dictates selective E2-E3 pairing as revealed by Ubc8/UBE2H-GID/CTLH assemblies.

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.

IKKß primes inflammasome formation by recruiting NLRP3 to the trans-Golgi network.

L-Arginine Modulates T Cell Metabolism and Enhances Survival and Anti-tumor Activity.

A human interactome in three quantitative dimensions organized by stoichiometries and abundances.

Widespread Proteome Remodeling and Aggregation in Aging C. elegans.

Unbiased spatial proteomics with single-cell resolution in tissues.

Social network architecture of human immune cells unveiled by quantitative proteomics.

The social and structural architecture of the yeast protein interactome.

Profiling the human intestinal environment under physiological conditions.

GID E3 ligase supramolecular chelate assembly configures multipronged ubiquitin targeting of an oligomeric metabolic enzyme.