Detalhe da pesquisa
1.
Phase 1b study of enzalutamide plus CC-115, a dual mTORC1/2 and DNA-PK inhibitor, in men with metastatic castration-resistant prostate cancer (mCRPC).
Br J Cancer
; 130(1): 53-62, 2024 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37980367
2.
Rapid interrogation of cancer cell of origin through CRISPR editing.
Proc Natl Acad Sci U S A
; 118(32)2021 08 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34353917
3.
The telomere capping complex CST has an unusual stoichiometry, makes multipartite interaction with G-Tails, and unfolds higher-order G-tail structures.
PLoS Genet
; 9(1): e1003145, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23300477
4.
Lysosome-dependent FOXA1 ubiquitination contributes to luminal lineage of advanced prostate cancer.
Mol Oncol
; 17(10): 2126-2146, 2023 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37491794
5.
ClC1 chloride channel in myotonic dystrophy type 2 and ClC1 splicing in vitro.
Acta Myol
; 31(2): 144-53, 2012 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-23097607
6.
Defining the therapeutic selective dependencies for distinct subtypes of PI3K pathway-altered prostate cancers.
Nat Commun
; 12(1): 5053, 2021 08 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-34417459
7.
AKT1 E17K Inhibits Cancer Cell Migration by Abrogating ß-Catenin Signaling.
Mol Cancer Res
; 19(4): 573-584, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33303690
8.
Role of Blm and collaborating factors in recombination and survival following replication stress in Ustilago maydis.
DNA Repair (Amst)
; 8(6): 752-9, 2009 Jun 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-19349216
9.
Oncogenic ERG Represses PI3K Signaling through Downregulation of IRS2.
Cancer Res
; 80(7): 1428-1437, 2020 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32015092
10.
ERG orchestrates chromatin interactions to drive prostate cell fate reprogramming.
J Clin Invest
; 130(11): 5924-5941, 2020 11 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-32701507
11.
Tumor Microenvironment-Derived NRG1 Promotes Antiandrogen Resistance in Prostate Cancer.
Cancer Cell
; 38(2): 279-296.e9, 2020 08 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32679108
12.
Dss1 regulates interaction of Brh2 with DNA.
Biochemistry
; 48(50): 11929-38, 2009 Dec 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-19919104
13.
Compensatory role for Rad52 during recombinational repair in Ustilago maydis.
Mol Microbiol
; 67(5): 1156-68, 2008 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-18208529
14.
Aberrant Expression of ERG Promotes Resistance to Combined PI3K and AR Pathway Inhibition through Maintenance of AR Target Genes.
Mol Cancer Ther
; 18(9): 1577-1586, 2019 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31296553
15.
Ortholog of BRCA2-interacting protein BCCIP controls morphogenetic responses during DNA replication stress in Ustilago maydis.
DNA Repair (Amst)
; 6(11): 1651-60, 2007 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-17627904
16.
Prostate-specific membrane antigen cleavage of vitamin B9 stimulates oncogenic signaling through metabotropic glutamate receptors.
J Exp Med
; 215(1): 159-175, 2018 01 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29141866
17.
Deletion of 3p13-14 locus spanning FOXP1 to SHQ1 cooperates with PTEN loss in prostate oncogenesis.
Nat Commun
; 8(1): 1081, 2017 10 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-29057879
18.
JAK2 inhibition sensitizes resistant EGFR-mutant lung adenocarcinoma to tyrosine kinase inhibitors.
Sci Signal
; 9(421): ra33, 2016 Mar 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-27025877
19.
Correction: Prostate-specific membrane antigen cleavage of vitamin B9 stimulates oncogenic signaling through metabotropic glutamate receptors.
J Exp Med
; 215(1): 377, 2018 01 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29183990
20.
Structural bases of dimerization of yeast telomere protein Cdc13 and its interaction with the catalytic subunit of DNA polymerase α.
Cell Res
; 21(2): 258-74, 2011 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-20877309