Detalhe da pesquisa
1.
Subcellular diversity of Nav1.5 in cardiomyocytes: distinct functions, mechanisms and targets.
J Physiol
; 601(5): 941-960, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36469003
2.
Recent advances and current limitations of available technology to optically manipulate and observe cardiac electrophysiology.
Pflugers Arch
; 475(11): 1357-1366, 2023 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-37770585
3.
Targeting the Microtubule EB1-CLASP2 Complex Modulates NaV1.5 at Intercalated Discs.
Circ Res
; 129(3): 349-365, 2021 07 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-34092082
4.
Oxidation of Protein Kinase A Regulatory Subunit PKARIα Protects Against Myocardial Ischemia-Reperfusion Injury by Inhibiting Lysosomal-Triggered Calcium Release.
Circulation
; 143(5): 449-465, 2021 02 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33185461
5.
Functional modulation of atrio-ventricular conduction by enhanced late sodium current and calcium-dependent mechanisms in Scn5a1798insD/+ mice.
Europace
; 22(10): 1579-1589, 2020 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32778883
6.
Absence of Functional Nav1.8 Channels in Non-diseased Atrial and Ventricular Cardiomyocytes.
Cardiovasc Drugs Ther
; 33(6): 649-660, 2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31916131
7.
A common co-morbidity modulates disease expression and treatment efficacy in inherited cardiac sodium channelopathy.
Eur Heart J
; 39(31): 2898-2907, 2018 08 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-29718149
8.
Functional Consequences of the SCN5A-p.Y1977N Mutation within the PY Ubiquitylation Motif: Discrepancy between HEK293 Cells and Transgenic Mice.
Int J Mol Sci
; 20(20)2019 Oct 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31614475
9.
Decreasing microtubule detyrosination modulates Nav1.5 subcellular distribution and restores sodium current in mdx cardiomyocytes.
Cardiovasc Res
; 2024 Feb 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-38395031
10.
Microtubule plus-end tracking proteins: novel modulators of cardiac sodium channels and arrhythmogenesis.
Cardiovasc Res
; 119(7): 1461-1479, 2023 07 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-37040608
11.
Optogenetic manipulation of cardiac repolarization gradients using sub-threshold illumination.
Front Physiol
; 14: 1167524, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37215182
12.
Differential Sodium Current Remodelling Identifies Distinct Cellular Proarrhythmic Mechanisms in Paroxysmal vs Persistent Atrial Fibrillation.
Can J Cardiol
; 39(3): 277-288, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36586483
13.
Desmosomal protein degradation as an underlying cause of arrhythmogenic cardiomyopathy.
Sci Transl Med
; 15(688): eadd4248, 2023 03 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-36947592
14.
Chronically elevated branched chain amino acid levels are pro-arrhythmic.
Cardiovasc Res
; 118(7): 1742-1757, 2022 06 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-34142125
15.
Low human dystrophin levels prevent cardiac electrophysiological and structural remodelling in a Duchenne mouse model.
Sci Rep
; 11(1): 9779, 2021 05 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33963238
16.
Patch-Clamp Recordings of Action Potentials From Human Atrial Myocytes: Optimization Through Dynamic Clamp.
Front Pharmacol
; 12: 649414, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33912059
17.
The sodium channel NaV 1.5 impacts on early murine embryonic cardiac development, structure and function in a non-electrogenic manner.
Acta Physiol (Oxf)
; 230(2): e13493, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32386467