Detalhe da pesquisa
1.
The 2-hydroxy-nevirapine metabolite as a candidate for boosting apolipoprotein A1 and for modulating anti-HDL antibodies.
Pharmacol Res
; 165: 105446, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33515705
2.
Covalent Histone Modification by an Electrophilic Derivative of the Anti-HIV Drug Nevirapine.
Molecules
; 26(5)2021 Mar 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33802579
3.
Nevirapine Biotransformation Insights: An Integrated In Vitro Approach Unveils the Biocompetence and Glutathiolomic Profile of a Human Hepatocyte-Like Cell 3D Model.
Int J Mol Sci
; 21(11)2020 Jun 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32503263
4.
Singularities of nevirapine metabolism: from sex-dependent differences to idiosyncratic toxicity.
Drug Metab Rev
; 51(1): 76-90, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30712401
5.
Synthesis, Crystal Structure, and Biological Evaluation of Fused Thiazolo[3,2-a]Pyrimidines as New Acetylcholinesterase Inhibitors.
Molecules
; 24(12)2019 Jun 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-31234400
6.
Carcinogenicity of aspartame, methyleugenol, and isoeugenol.
Lancet Oncol
; 24(8): 848-850, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37454664
7.
Hepatocyte spheroids as a competent in vitro system for drug biotransformation studies: nevirapine as a bioactivation case study.
Arch Toxicol
; 91(3): 1199-1211, 2017 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-27417440
8.
Differences in nevirapine biotransformation as a factor for its sex-dependent dimorphic profile of adverse drug reactions.
J Antimicrob Chemother
; 69(2): 476-82, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-24051761
9.
Mechanistic insights into the cytotoxicity and genotoxicity induced by glycidamide in human mammary cells.
Mutagenesis
; 28(6): 721-9, 2013 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-24150595
10.
Synthesis and evaluation of diaryl sulfides and diaryl selenide compounds for antitubulin and cytotoxic activity.
Bioorg Med Chem Lett
; 23(16): 4669-73, 2013 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23810282
11.
2'-Deoxythymidine adducts from the anti-HIV drug nevirapine.
Molecules
; 18(5): 4955-71, 2013 Apr 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-23624649
12.
Biomimetic oxidation of aromatic xenobiotics: synthesis of the phenolic metabolites from the anti-HIV drug efavirenz.
Org Biomol Chem
; 10(23): 4554-61, 2012 Jun 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-22569890
13.
Oxidation of 2-hydroxynevirapine, a phenolic metabolite of the anti-HIV drug nevirapine: evidence for an unusual pyridine ring contraction.
Molecules
; 17(3): 2616-27, 2012 Mar 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-22391597
14.
The mechanisms underlying montelukast's neuropsychiatric effects - new insights from a combined metabolic and multiomics approach.
Life Sci
; 310: 121056, 2022 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36228771
15.
Reactive aldehyde metabolites from the anti-HIV drug abacavir: amino acid adducts as possible factors in abacavir toxicity.
Chem Res Toxicol
; 24(12): 2129-41, 2011 Dec 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-22032494
16.
Synthesis and oxidation of 2-hydroxynevirapine, a metabolite of the HIV reverse transcriptase inhibitor nevirapine.
Org Biomol Chem
; 9(22): 7822-35, 2011 Oct 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-21969039
17.
Acetaminophen Induces an Antioxidative Response in Lettuce Plants.
Plants (Basel)
; 10(6)2021 Jun 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-34204080
18.
Antimicrobial and antitumor activity of S-methyl dithiocarbazate Schiff base zinc(II) complexes.
J Inorg Biochem
; 216: 111331, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33348167
19.
Amino acid adduct formation by the nevirapine metabolite, 12-hydroxynevirapine--a possible factor in nevirapine toxicity.
Chem Res Toxicol
; 23(5): 888-99, 2010 May 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-20392079
20.
High-performance liquid chromatography electrospray ionization tandem mass spectrometry for the detection and quantitation of pyrrolizidine alkaloid-derived DNA adducts in vitro and in vivo.
Chem Res Toxicol
; 23(3): 637-52, 2010 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20078085