Detalhe da pesquisa
1.
Proteostatic imbalance and protein spreading in amyotrophic lateral sclerosis.
EMBO J
; 40(10): e106389, 2021 05 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-33792056
2.
SPG15 protein deficits are at the crossroads between lysosomal abnormalities, altered lipid metabolism and synaptic dysfunction.
Hum Mol Genet
; 31(16): 2693-2710, 2022 08 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-35313342
3.
FUS pathology in ALS is linked to alterations in multiple ALS-associated proteins and rescued by drugs stimulating autophagy.
Acta Neuropathol
; 138(1): 67-84, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30937520
4.
Brain oxygen tension controls the expansion of outer subventricular zone-like basal progenitors in the developing mouse brain.
Development
; 142(17): 2904-15, 2015 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26329599
5.
Circumventing the packaging limit of AAV-mediated gene replacement therapy for neurological disorders.
Expert Opin Biol Ther
; 22(9): 1163-1176, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34904932
6.
SMN-deficient cells exhibit increased ribosomal DNA damage.
Life Sci Alliance
; 5(8)2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35440492
7.
C9ORF72-derived poly-GA DPRs undergo endocytic uptake in iAstrocytes and spread to motor neurons.
Life Sci Alliance
; 5(9)2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35568435
8.
Phenotypic Screening Using Mouse and Human Stem Cell-Based Models of Neuroinflammation and Gene Expression Analysis to Study Drug Responses.
Methods Mol Biol
; 1888: 21-43, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-30519939
9.
Muscleblind acts as a modifier of FUS toxicity by modulating stress granule dynamics and SMN localization.
Nat Commun
; 10(1): 5583, 2019 12 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31811140
10.
Dual Inhibition of GSK3ß and CDK5 Protects the Cytoskeleton of Neurons from Neuroinflammatory-Mediated Degeneration In Vitro and In Vivo.
Stem Cell Reports
; 12(3): 502-517, 2019 03 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30773488
11.
RNA buffers the phase separation behavior of prion-like RNA binding proteins.
Science
; 360(6391): 918-921, 2018 05 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-29650702
12.
Generation of iPSCs carrying a common LRRK2 risk allele for in vitro modeling of idiopathic Parkinson's disease.
PLoS One
; 13(3): e0192497, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29513666
13.
Isogenic FUS-eGFP iPSC Reporter Lines Enable Quantification of FUS Stress Granule Pathology that Is Rescued by Drugs Inducing Autophagy.
Stem Cell Reports
; 10(2): 375-389, 2018 02 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-29358088
14.
Delivery of therapeutic AAV9 vectors via cisterna magna to treat neurological disorders.
Trends Mol Med
; 28(1): 79-80, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34756547
15.
Primary Spinal OPC Culture System from Adult Zebrafish to Study Oligodendrocyte Differentiation In Vitro.
Front Cell Neurosci
; 11: 284, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28959189
16.
Oxygen Tension Within the Neurogenic Niche Regulates Dopaminergic Neurogenesis in the Developing Midbrain.
Stem Cells Dev
; 25(3): 227-38, 2016 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26577812
17.
Adoptive T-cell therapy in the treatment of viral and opportunistic fungal infections.
Future Microbiol
; 10(4): 665-82, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25865200