Detalhe da pesquisa
1.
Let's get fat: emergence of S-acylation as a therapeutic target in Huntington disease.
Biochem Soc Trans
; 52(3): 1385-1392, 2024 Jun 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-38695682
2.
Rescue of aberrant huntingtin palmitoylation ameliorates mutant huntingtin-induced toxicity.
Neurobiol Dis
; 158: 105479, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34390831
3.
Identification of a novel caspase cleavage site in huntingtin that regulates mutant huntingtin clearance.
FASEB J
; 33(3): 3190-3197, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30423259
4.
Neurodegeneration: Role of repeats in protein clearance.
Nature
; 545(7652): 33-34, 2017 05 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28445458
5.
Identification of a post-translationally myristoylated autophagy-inducing domain released by caspase cleavage of huntingtin.
Hum Mol Genet
; 23(12): 3166-79, 2014 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24459296
6.
The palmitoyl acyltransferase HIP14 shares a high proportion of interactors with huntingtin: implications for a role in the pathogenesis of Huntington's disease.
Hum Mol Genet
; 23(15): 4142-60, 2014 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24705354
7.
Curation of the Mammalian Palmitoylome Indicates a Pivotal Role for Palmitoylation in Diseases and Disorders of the Nervous System and Cancers.
PLoS Comput Biol
; 11(8): e1004405, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-26275289
8.
Partial rescue of some features of Huntington Disease in the genetic absence of caspase-6 in YAC128 mice.
Neurobiol Dis
; 76: 24-36, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25583186
9.
The Salmonella type III effector SspH2 specifically exploits the NLR co-chaperone activity of SGT1 to subvert immunity.
PLoS Pathog
; 9(7): e1003518, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23935490
10.
Post-translational myristoylation at the cross roads of cell death, autophagy and neurodegeneration.
Biochem Soc Trans
; 43(2): 229-34, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25849922
11.
Regulation of co- and post-translational myristoylation of proteins during apoptosis: interplay of N-myristoyltransferases and caspases.
FASEB J
; 27(2): 811-21, 2013 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-23150525
12.
Systemic delivery of mutant huntingtin lowering antisense oligonucleotides to the brain using apolipoprotein A-I nanodisks for Huntington disease.
J Control Release
; 367: 27-44, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38215984
13.
Tandem reporter assay for myristoylated proteins post-translationally (TRAMPP) identifies novel substrates for post-translational myristoylation: PKCε, a case study.
FASEB J
; 26(1): 13-28, 2012 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-21965604
14.
Full-length huntingtin is palmitoylated at multiple sites and post-translationally myristoylated following caspase-cleavage.
Front Physiol
; 14: 1086112, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36711022
15.
Lost in traffic: consequences of altered palmitoylation in neurodegeneration.
Front Physiol
; 14: 1166125, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37324388
16.
Delivery of mutant huntingtin-lowering antisense oligonucleotides to the brain by intranasally administered apolipoprotein A-I nanodisks.
J Control Release
; 360: 913-927, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37468110
17.
The human Dcn1-like protein DCNL3 promotes Cul3 neddylation at membranes.
Proc Natl Acad Sci U S A
; 106(30): 12365-70, 2009 Jul 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-19617556
18.
Optimized Incorporation of Alkynyl Fatty Acid Analogs for the Detection of Fatty Acylated Proteins using Click Chemistry.
J Vis Exp
; (170)2021 04 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-33900285
19.
Rapid and selective detection of fatty acylated proteins using omega-alkynyl-fatty acids and click chemistry.
J Lipid Res
; 51(6): 1566-80, 2010 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-20028662
20.
Surface study of apoB1694-1880, a sequence that can anchor apoB to lipoproteins and make it nonexchangeable.
J Lipid Res
; 50(7): 1340-52, 2009 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-19251580