Pesquisa | Portal de Pesquisa da BVS Enfermagem

1.

HLA-DR15 Molecules Jointly Shape an Autoreactive T Cell Repertoire in Multiple Sclerosis.

Wang, Jian; Jelcic, Ivan; Mühlenbruch, Lena; Haunerdinger, Veronika; Toussaint, Nora C; Zhao, Yingdong; Cruciani, Carolina; Faigle, Wolfgang; Naghavian, Reza; Foege, Magdalena; Binder, Thomas M C; Eiermann, Thomas; Opitz, Lennart; Fuentes-Font, Laura; Reynolds, Richard; Kwok, William W; Nguyen, Julie T; Lee, Jar-How; Lutterotti, Andreas; Münz, Christian; Rammensee, Hans-Georg; Hauri-Hohl, Mathias; Sospedra, Mireia; Stevanovic, Stefan; Martin, Roland.

Cell ; 183(5): 1264-1281.e20, 2020 11 25.

Artigo em Inglês | MEDLINE | ID: mdl-33091337

2.

Memory B Cells Activate Brain-Homing, Autoreactive CD4⁺ T Cells in Multiple Sclerosis.

Jelcic, Ivan; Al Nimer, Faiez; Wang, Jian; Lentsch, Verena; Planas, Raquel; Jelcic, Ilijas; Madjovski, Aleksandar; Ruhrmann, Sabrina; Faigle, Wolfgang; Frauenknecht, Katrin; Pinilla, Clemencia; Santos, Radleigh; Hammer, Christian; Ortiz, Yaneth; Opitz, Lennart; Grönlund, Hans; Rogler, Gerhard; Boyman, Onur; Reynolds, Richard; Lutterotti, Andreas; Khademi, Mohsen; Olsson, Tomas; Piehl, Fredrik; Sospedra, Mireia; Martin, Roland.

Cell ; 175(1): 85-100.e23, 2018 09 20.

Artigo em Inglês | MEDLINE | ID: mdl-30173916

3.

Microbial peptides activate tumour-infiltrating lymphocytes in glioblastoma.

Naghavian, Reza; Faigle, Wolfgang; Oldrati, Pietro; Wang, Jian; Toussaint, Nora C; Qiu, Yuhan; Medici, Gioele; Wacker, Marcel; Freudenmann, Lena K; Bonté, Pierre-Emmanuel; Weller, Michael; Regli, Luca; Amigorena, Sebastian; Rammensee, Hans-Georg; Walz, Juliane S; Brugger, Silvio D; Mohme, Malte; Zhao, Yingdong; Sospedra, Mireia; Neidert, Marian C; Martin, Roland.

Nature ; 617(7962): 807-817, 2023 05.

Artigo em Inglês | MEDLINE | ID: mdl-37198490

4.

Targeting fibrin in neurodegeneration.

Martin, Roland.

Nat Immunol ; 19(11): 1149-1150, 2018 11.

Artigo em Inglês | MEDLINE | ID: mdl-30323342

5.

HLA Associations of Intrathecal IgG Production against Specific Viruses in Multiple Sclerosis.

Neidhart, Stephan; Vlad, Benjamin; Hilty, Marc; Högelin, Klara Asplund; Ziegler, Mario; Berenjeno-Correa, Ernesto; Reichen, Ina; Stridh, Pernilla; Jelcic, Ivan; Khademi, Mohsen; Kockum, Ingrid; Sospedra, Mireia; Al Nimer, Faiez; Martin, Roland; Jelcic, Ilijas.

Ann Neurol ; 2024 Mar 29.

Artigo em Inglês | MEDLINE | ID: mdl-38551149

6.

Determinants and Biomarkers of Progression Independent of Relapses in Multiple Sclerosis.

Calabrese, Massimiliano; Preziosa, Paolo; Scalfari, Antonio; Colato, Elisa; Marastoni, Damiano; Absinta, Martina; Battaglini, Marco; De Stefano, Nicola; Di Filippo, Massimiliano; Hametner, Simon; Howell, Owain W; Inglese, Matilde; Lassmann, Hans; Martin, Roland; Nicholas, Richard; Reynolds, Richard; Rocca, Maria A; Tamanti, Agnese; Vercellino, Marco; Villar, Luisa Maria; Filippi, Massimo; Magliozzi, Roberta.

Ann Neurol ; 2024 Apr 03.

Artigo em Inglês | MEDLINE | ID: mdl-38568026

7.

Multiple sclerosis: doubling down on MHC.

Martin, Roland; Sospedra, Mireia; Eiermann, Thomas; Olsson, Tomas.

Trends Genet ; 37(9): 784-797, 2021 09.

Artigo em Inglês | MEDLINE | ID: mdl-34006391

8.

Attenuated immune control of Epstein-Barr virus in humanized mice is associated with the multiple sclerosis risk factor HLA-DR15.

Zdimerova, Hana; Murer, Anita; Engelmann, Christine; Raykova, Ana; Deng, Yun; Gujer, Cornelia; Rühl, Julia; McHugh, Donal; Caduff, Nicole; Naghavian, Reza; Pezzino, Gaetana; Capaul, Riccarda; Zbinden, Andrea; Ferlazzo, Guido; Lünemann, Jan D; Martin, Roland; Chatterjee, Bithi; Münz, Christian.

Eur J Immunol ; 51(1): 64-75, 2021 01.

Artigo em Inglês | MEDLINE | ID: mdl-32949466

9.

MAPK pathway and B cells overactivation in multiple sclerosis revealed by phosphoproteomics and genomic analysis.

Kotelnikova, Ekaterina; Kiani, Narsis A; Messinis, Dimitris; Pertsovskaya, Inna; Pliaka, Vicky; Bernardo-Faura, Marti; Rinas, Melanie; Vila, Gemma; Zubizarreta, Irati; Pulido-Valdeolivas, Irene; Sakellaropoulos, Theodore; Faigle, Wolfgang; Silberberg, Gilad; Masso, Mar; Stridh, Pernilla; Behrens, Janina; Olsson, Tomas; Martin, Roland; Paul, Friedemann; Alexopoulos, Leonidas G; Saez-Rodriguez, Julio; Tegner, Jesper; Villoslada, Pablo.

Proc Natl Acad Sci U S A ; 116(19): 9671-9676, 2019 05 07.

Artigo em Inglês | MEDLINE | ID: mdl-31004050

10.

Dynamics of Inflammatory and Neurodegenerative Biomarkers after Autologous Hematopoietic Stem Cell Transplantation in Multiple Sclerosis.

Ruder, Josefine; Dinner, Gianna; Maceski, Aleksandra; Berenjeno-Correa, Ernesto; Müller, Antonia Maria; Jelcic, Ilijas; Kuhle, Jens; Martin, Roland.

Int J Mol Sci ; 23(18)2022 Sep 19.

Artigo em Inglês | MEDLINE | ID: mdl-36142860

11.

Differential Expression of Serum Extracellular Vesicle miRNAs in Multiple Sclerosis: Disease-Stage Specificity and Relevance to Pathophysiology.

Cuomo-Haymour, Nagiua; Bergamini, Giorgio; Russo, Giancarlo; Kulic, Luka; Knuesel, Irene; Martin, Roland; Huss, André; Tumani, Hayrettin; Otto, Markus; Pryce, Christopher R.

Int J Mol Sci ; 23(3)2022 Jan 31.

Artigo em Inglês | MEDLINE | ID: mdl-35163583

12.

The 3A6-TCR/superagonist/HLA-DR2a complex shows similar interface and reduced flexibility compared to the complex with self-peptide.

Salutari, Ilaria; Martin, Roland; Caflisch, Amedeo.

Proteins ; 88(1): 31-46, 2020 01.

Artigo em Inglês | MEDLINE | ID: mdl-31237711

13.

Exploring the origins of grey matter damage in multiple sclerosis.

Calabrese, Massimiliano; Magliozzi, Roberta; Ciccarelli, Olga; Geurts, Jeroen J G; Reynolds, Richard; Martin, Roland.

Nat Rev Neurosci ; 16(3): 147-58, 2015 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-25697158

14.

In search of cerebrospinal fluid biomarkers of fatigue in multiple sclerosis: A proteomics study.

Valko, Philipp O; Roschitzki, Bernd; Faigle, Wolfgang; Grossmann, Jonas; Panse, Christian; Biro, Peter; Dambach, Micha; Spahn, Donat R; Weller, Michael; Martin, Roland; Baumann, Christian R.

J Sleep Res ; 28(3): e12721, 2019 06.

Artigo em Inglês | MEDLINE | ID: mdl-29961995

15.

Unfavorable Structural and Functional Outcomes in Myelin Oligodendrocyte Glycoprotein Antibody-Associated Optic Neuritis.

Jelcic, Ilijas; Hanson, James V M; Lukas, Sebastian; Weber, Konrad P; Landau, Klara; Pless, Misha; Reindl, Markus; Weller, Michael; Martin, Roland; Lutterotti, Andreas; Schippling, Sven.

J Neuroophthalmol ; 39(1): 3-7, 2019 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-30015656

16.

A standardised frankincense extract reduces disease activity in relapsing-remitting multiple sclerosis (the SABA phase IIa trial).

Stürner, Klarissa Hanja; Stellmann, Jan-Patrick; Dörr, Jan; Paul, Friedemann; Friede, Tim; Schammler, Sven; Reinhardt, Stefanie; Gellissen, Susanne; Weissflog, Gainet; Faizy, Tobias Djamsched; Werz, Oliver; Fleischer, Sabine; Vaas, Lea A I; Herrmann, Frank; Pless, Ole; Martin, Roland; Heesen, Christoph.

J Neurol Neurosurg Psychiatry ; 89(4): 330-338, 2018 04.

Artigo em Inglês | MEDLINE | ID: mdl-29248894

17.

Dynamics and heterogeneity of brain damage in multiple sclerosis.

Kotelnikova, Ekaterina; Kiani, Narsis A; Abad, Elena; Martinez-Lapiscina, Elena H; Andorra, Magi; Zubizarreta, Irati; Pulido-Valdeolivas, Irene; Pertsovskaya, Inna; Alexopoulos, Leonidas G; Olsson, Tomas; Martin, Roland; Paul, Friedemann; Tegnér, Jesper; Garcia-Ojalvo, Jordi; Villoslada, Pablo.

PLoS Comput Biol ; 13(10): e1005757, 2017 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-29073203

18.

Current multiple sclerosis treatments have improved our understanding of MS autoimmune pathogenesis.

Martin, Roland; Sospedra, Mireia; Rosito, Maria; Engelhardt, Britta.

Eur J Immunol ; 46(9): 2078-90, 2016 09.

Artigo em Inglês | MEDLINE | ID: mdl-27467894

19.

Mechanisms of immune escape in central nervous system infection with neurotropic JC virus variant.

Jelcic, Ivan; Jelcic, Ilijas; Kempf, Christian; Largey, Fabienne; Planas, Raquel; Schippling, Sven; Budka, Herbert; Sospedra, Mireia; Martin, Roland.

Ann Neurol ; 79(3): 404-18, 2016 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-26874214

20.

Nogo-A antibodies enhance axonal repair and remyelination in neuro-inflammatory and demyelinating pathology.

Ineichen, Benjamin V; Kapitza, Sandra; Bleul, Christiane; Good, Nicolas; Plattner, Patricia S; Seyedsadr, Maryam S; Kaiser, Julia; Schneider, Marc P; Zörner, Björn; Martin, Roland; Linnebank, Michael; Schwab, Martin E.

Acta Neuropathol ; 134(3): 423-440, 2017 09.

Artigo em Inglês | MEDLINE | ID: mdl-28646336

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