Detalhe da pesquisa
1.
Functional Profiling of a Plasmodium Genome Reveals an Abundance of Essential Genes.
Cell
; 170(2): 260-272.e8, 2017 07 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-28708996
2.
Inferring a complete genotype-phenotype map from a small number of measured phenotypes.
PLoS Comput Biol
; 16(9): e1008243, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32991585
3.
The Malaria Parasite's Lactate Transporter PfFNT Is the Target of Antiplasmodial Compounds Identified in Whole Cell Phenotypic Screens.
PLoS Pathog
; 13(2): e1006180, 2017 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-28178359
4.
Molecular Mechanisms for Drug Hypersensitivity Induced by the Malaria Parasite's Chloroquine Resistance Transporter.
PLoS Pathog
; 12(7): e1005725, 2016 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27441371
5.
Diverse mutational pathways converge on saturable chloroquine transport via the malaria parasite's chloroquine resistance transporter.
Proc Natl Acad Sci U S A
; 111(17): E1759-67, 2014 Apr 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-24728833
6.
Verapamil-Sensitive Transport of Quinacrine and Methylene Blue via the Plasmodium falciparum Chloroquine Resistance Transporter Reduces the Parasite's Susceptibility to these Tricyclic Drugs.
J Infect Dis
; 213(5): 800-10, 2016 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26503982
7.
Multiple drugs compete for transport via the Plasmodium falciparum chloroquine resistance transporter at distinct but interdependent sites.
J Biol Chem
; 289(52): 36336-51, 2014 Dec 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-25378409
8.
Know your enemy: understanding the role of PfCRT in drug resistance could lead to new antimalarial tactics.
Cell Mol Life Sci
; 69(12): 1967-95, 2012 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-22286067
9.
Saquinavir inhibits the malaria parasite's chloroquine resistance transporter.
Antimicrob Agents Chemother
; 56(5): 2283-9, 2012 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-22354298
10.
Sodium-dependent uptake of inorganic phosphate by the intracellular malaria parasite.
Nature
; 443(7111): 582-5, 2006 Oct 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-17006451
11.
Identifying the major lactate transporter of Toxoplasma gondii tachyzoites.
Sci Rep
; 11(1): 6787, 2021 03 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-33762657
12.
Synthesis and biological evaluation of benzhydryl-based antiplasmodial agents possessing Plasmodium falciparum chloroquine resistance transporter (PfCRT) inhibitory activity.
Eur J Med Chem
; 215: 113227, 2021 Apr 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33601312
13.
Membrane transport proteins of the malaria parasite.
Mol Microbiol
; 74(3): 519-28, 2009 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-19796339
14.
The transportome of the malaria parasite.
Biol Rev Camb Philos Soc
; 95(2): 305-332, 2020 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-31701663
15.
The natural function of the malaria parasite's chloroquine resistance transporter.
Nat Commun
; 11(1): 3922, 2020 08 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32764664
16.
Characterization of a Dopamine Transporter and Its Splice Variant Reveals Novel Features of Dopaminergic Regulation in the Honey Bee.
Front Physiol
; 10: 1375, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31736791
17.
Mechanisms of resistance to the partner drugs of artemisinin in the malaria parasite.
Curr Opin Pharmacol
; 42: 71-80, 2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30142480
18.
Globally prevalent PfMDR1 mutations modulate Plasmodium falciparum susceptibility to artemisinin-based combination therapies.
Nat Commun
; 7: 11553, 2016 05 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-27189525
19.
A lactate and formate transporter in the intraerythrocytic malaria parasite, Plasmodium falciparum.
Nat Commun
; 6: 6721, 2015 Mar 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-25823844
20.
Mutations in the Plasmodium falciparum chloroquine resistance transporter, PfCRT, enlarge the parasite's food vacuole and alter drug sensitivities.
Sci Rep
; 5: 14552, 2015 Sep 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-26420308