Detalhe da pesquisa
1.
Genome engineering of isogenic human ES cells to model autism disorders.
Nucleic Acids Res
; 43(10): e65, 2015 May 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-25765640
2.
AAV-mediated interneuron-specific gene replacement for Dravet syndrome.
bioRxiv
; 2023 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38168178
3.
Enhancer-AAVs allow genetic access to oligodendrocytes and diverse populations of astrocytes across species.
bioRxiv
; 2023 Sep 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-37790503
4.
Reduced gene dosage is a common mechanism of neuropathologies caused by ATP6AP2 splicing mutations.
Parkinsonism Relat Disord
; 101: 31-38, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35779466
5.
Functional enhancer elements drive subclass-selective expression from mouse to primate neocortex.
Cell Rep
; 34(13): 108754, 2021 03 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-33789096
6.
Polyglutamine-expanded androgen receptor truncation fragments activate a Bax-dependent apoptotic cascade mediated by DP5/Hrk.
J Neurosci
; 29(7): 1987-97, 2009 Feb 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-19228953
7.
The zinc-binding domain of Nna1 is required to prevent retinal photoreceptor loss and cerebellar ataxia in Purkinje cell degeneration (pcd) mice.
Vision Res
; 48(19): 1999-2005, 2008 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-18602413
8.
Dynamics of embryonic stem cell differentiation inferred from single-cell transcriptomics show a series of transitions through discrete cell states.
Elife
; 62017 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28296635
9.
A Single-Cell Roadmap of Lineage Bifurcation in Human ESC Models of Embryonic Brain Development.
Cell Stem Cell
; 20(1): 120-134, 2017 01 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28094016
10.
Polyglutamine-expanded ataxin-7 promotes non-cell-autonomous purkinje cell degeneration and displays proteolytic cleavage in ataxic transgenic mice.
J Neurosci
; 22(12): 4897-905, 2002 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-12077187
11.
CORTECON: a temporal transcriptome analysis of in vitro human cerebral cortex development from human embryonic stem cells.
Neuron
; 83(1): 51-68, 2014 Jul 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-24991954
12.
Nutrient deprivation induces neuronal autophagy and implicates reduced insulin signaling in neuroprotective autophagy activation.
J Biol Chem
; 284(4): 2363-73, 2009 Jan 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-19017649
13.
The Purkinje cell degeneration 5J mutation is a single amino acid insertion that destabilizes Nna1 protein.
Mamm Genome
; 17(2): 103-10, 2006 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-16465590
14.
Genomic context drives SCA7 CAG repeat instability, while expressed SCA7 cDNAs are intergenerationally and somatically stable in transgenic mice.
Hum Mol Genet
; 12(1): 41-50, 2003 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-12490531