Detalhe da pesquisa
1.
Disrupting the adult globin promoter alleviates promoter competition and reactivates fetal globin gene expression.
Blood
; 139(14): 2107-2118, 2022 04 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35090172
2.
Identification of Protein Isoforms Using Reference Databases Built from Long and Short Read RNA-Sequencing.
J Proteome Res
; 21(7): 1628-1639, 2022 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35612954
3.
Wake-up Sleepy Gene: Reactivating Fetal Globin for ß-Hemoglobinopathies.
Trends Genet
; 34(12): 927-940, 2018 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30287096
4.
A natural regulatory mutation in the proximal promoter elevates fetal globin expression by creating a de novo GATA1 site.
Blood
; 133(8): 852-856, 2019 02 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-30617196
5.
KLF1 drives the expression of fetal hemoglobin in British HPFH.
Blood
; 130(6): 803-807, 2017 08 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-28659276
6.
Differential regulation of the α-globin locus by Krüppel-like Factor 3 in erythroid and non-erythroid cells.
BMC Mol Biol
; 15: 8, 2014 May 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-24885809
7.
Rewriting regulatory DNA to dissect and reprogram gene expression.
bioRxiv
; 2023 Dec 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-38187584
8.
Phenotypic screen for oxygen consumption rate identifies an anti-cancer naphthoquinone that induces mitochondrial oxidative stress.
Redox Biol
; 28: 101374, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31743887
9.
Natural regulatory mutations elevate the fetal globin gene via disruption of BCL11A or ZBTB7A binding.
Nat Genet
; 50(4): 498-503, 2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29610478
10.
The regulation of human globin promoters by CCAAT box elements and the recruitment of NF-Y.
Biochim Biophys Acta Gene Regul Mech
; 1860(5): 525-536, 2017 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-27718361
11.
Transcription factors LRF and BCL11A independently repress expression of fetal hemoglobin.
Science
; 351(6270): 285-9, 2016 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26816381