Detalhe da pesquisa
1.
Germline variation in RASAL2 may predict survival in patients with RAS-activated colorectal cancer.
Genes Chromosomes Cancer
; 62(6): 332-341, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36790221
2.
Activation of innate-adaptive immune machinery by poly(I:C) exposes a therapeutic vulnerability to prevent relapse in stroma-rich colon cancer.
Gut
; 71(12): 2502-2517, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35477539
3.
Genetic variation in ST6GAL1 is a determinant of capecitabine and oxaliplatin induced hand-foot syndrome.
Int J Cancer
; 151(6): 957-966, 2022 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35467766
4.
Clinicopathological and molecular characteristics of RSPO fusion-positive colorectal cancer.
Br J Cancer
; 127(6): 1043-1050, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35715628
5.
TET2 Drives 5hmc Marking of GATA6 and Epigenetically Defines Pancreatic Ductal Adenocarcinoma Transcriptional Subtypes.
Gastroenterology
; 161(2): 653-668.e16, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33915173
6.
Experiences of running a stratified medicine adaptive platform trial: Challenges and lessons learned from 10 years of the FOCUS4 trial in metastatic colorectal cancer.
Clin Trials
; 19(2): 146-157, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35083924
7.
Image-based consensus molecular subtype (imCMS) classification of colorectal cancer using deep learning.
Gut
; 70(3): 544-554, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32690604
8.
Genome-wide association studies of toxicity to oxaliplatin and fluoropyrimidine chemotherapy with or without cetuximab in 1800 patients with advanced colorectal cancer.
Int J Cancer
; 149(9): 1713-1722, 2021 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34270794
9.
Exploiting differential Wnt target gene expression to generate a molecular biomarker for colorectal cancer stratification.
Gut
; 69(6): 1092-1103, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31563876
10.
Systemic chemotherapy with or without cetuximab in patients with resectable colorectal liver metastasis (New EPOC): long-term results of a multicentre, randomised, controlled, phase 3 trial.
Lancet Oncol
; 21(3): 398-411, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32014119
11.
Study protocol: a multi-centre randomised study of induction chemotherapy followed by capecitabine ± nelfinavir with high- or standard-dose radiotherapy for locally advanced pancreatic cancer (SCALOP-2).
BMC Cancer
; 19(1): 121, 2019 Feb 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30717707
12.
Variation at 2q35 (PNKD and TMBIM1) influences colorectal cancer risk and identifies a pleiotropic effect with inflammatory bowel disease.
Hum Mol Genet
; 25(11): 2349-2359, 2016 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27005424
13.
Comprehensive pharmacogenetic profiling of the epidermal growth factor receptor pathway for biomarkers of response to, and toxicity from, cetuximab.
J Med Genet
; 54(8): 567-571, 2017 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-28283541
14.
Mendelian randomisation implicates hyperlipidaemia as a risk factor for colorectal cancer.
Int J Cancer
; 140(12): 2701-2708, 2017 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28340513
15.
Testing many treatments within a single protocol over 10 years at MRC Clinical Trials Unit at UCL: Multi-arm, multi-stage platform, umbrella and basket protocols.
Clin Trials
; 14(5): 451-461, 2017 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-28830236
16.
Prognosis of patients with peritoneal metastatic colorectal cancer given systemic therapy: an analysis of individual patient data from prospective randomised trials from the Analysis and Research in Cancers of the Digestive System (ARCAD) database.
Lancet Oncol
; 17(12): 1709-1719, 2016 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-27743922
17.
Common genetic variation and survival after colorectal cancer diagnosis: a genome-wide analysis.
Carcinogenesis
; 37(1): 87-95, 2016 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-26586795
18.
Mendelian randomisation analysis strongly implicates adiposity with risk of developing colorectal cancer.
Br J Cancer
; 115(2): 266-72, 2016 Jul 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27336604
19.
NEOSCOPE: a randomised Phase II study of induction chemotherapy followed by either oxaliplatin/capecitabine or paclitaxel/carboplatin based chemoradiation as pre-operative regimen for resectable oesophageal adenocarcinoma.
BMC Cancer
; 15: 48, 2015 Feb 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-25880814
20.
Panitumumab and irinotecan versus irinotecan alone for patients with KRAS wild-type, fluorouracil-resistant advanced colorectal cancer (PICCOLO): a prospectively stratified randomised trial.
Lancet Oncol
; 14(8): 749-59, 2013 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-23725851