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Dog vaccination is the key to controlling rabies in human populations. However, in countries like India, with large free-roaming dog populations, vaccination strategies that rely only on parenteral vaccines are unlikely to be either feasible or successful. Oral rabies vaccines could be used to reach these dogs. We use cost estimates for an Indian city and linear optimisation to find the most cost-effective vaccination strategies. We show that an oral bait handout method for dogs that are never confined can reduce the per dog costs of vaccination and increase vaccine coverage. This finding holds even when baits cost up to 10x the price of parenteral vaccines, if there is a large dog population or proportion of dogs that are never confined. We suggest that oral rabies vaccine baits will be part of the most cost-effective strategies to eliminate human deaths from dog-mediated rabies by 2030.
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Doenças do Cão , Vacina Antirrábica , Raiva , Animais , Cães , Humanos , Raiva/prevenção & controle , Raiva/veterinária , Doenças do Cão/prevenção & controle , Doenças do Cão/epidemiologia , Vacinação/veterinária , Vacinação/métodos , Índia/epidemiologiaRESUMO
Online gambling poses novel risks for problem gambling, but also unique opportunities to detect and intervene with at-risk users. A consortium of gambling companies recently committed to using nine behavioral "Markers of Harm'' that can be calculated with online user data to estimate risk for gambling-related harm. The current study evaluates these markers in two independent samples of sports bettors, collected ten years apart. We find over a two-year period that most users never had high enough overall risk scores to indicate that they would have received an intervention. This observation is partly due to characteristics of our samples that are associated with lower risk for gambling-related harm, but might also be due to overly high risk thresholds or flaws in the design of some markers. Users with higher average risk scores had more intraindividual variability in risk scores. Younger age and male gender were not associated with higher average risk scores. The most active users were more likely than other users to have ever exceeded risk thresholds. Several risk scores significantly predicted proxies of gambling-related harm (e.g., account closure). Overall, the current Markers of Harm system has some correctable limitations that future risk detection systems should consider adopting.
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Jogo de Azar , Esportes , Masculino , Humanos , Jogo de Azar/psicologia , Fatores de RiscoRESUMO
We conducted a series of meta-analytic tests on experiments in which participants read perspective-taking instructions-that is, written instructions to imagine a distressed persons' point of view ("imagine-self" and "imagine-other" instructions), or to inhibit such actions ("remain-objective" instructions)-and afterwards reported how much empathic concern they experienced upon learning about the distressed person. If people spontaneously empathize with others, then participants who receive remain-objective instructions should report less empathic concern than do participants in a "no-instructions" control condition; if people can deliberately increase how much empathic concern they experience, then imagine-self and imagine-other instructions should increase empathic concern relative to not receiving any instructions. Random-effects models revealed that remain-objective instructions reduced empathic concern, but "imagine" instructions did not significantly increase it. The results were robust to most corrections for bias. Our conclusions were not qualified by the study characteristics we examined, but most relevant moderators have not yet been thoroughly studied.
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Rede de Modo Padrão/fisiologia , Emoções/fisiologia , Empatia/fisiologia , Imaginação/fisiologia , Dor/fisiopatologia , Dor/psicologia , Adulto , Altruísmo , Conscientização/fisiologia , Humanos , Relações InterpessoaisRESUMO
We offer a friendly criticism of May's fantastic book on moral reasoning: It is overly charitable to the argument that moral disagreement undermines moral knowledge. To highlight the role that reasoning quality plays in moral judgments, we review literature that he did not mention showing that individual differences in intelligence and cognitive reflection explain much of moral disagreement. The burden is on skeptics of moral knowledge to show that moral disagreement arises from non-rational origins.
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When people experience empathy for a needy stranger, efforts to help are often not far behind. But does empathy actually cause prosocial behavior? And if so, does it activate genuine concern or more self-interested motivations? To rule out the alternative hypothesis that empathy motivates prosocial behavior by generating fear of social disapproval for acting selfishly, Fultz et al. (1986) manipulated empathy for a lonely stranger using perspective-taking instructions; they also manipulated whether subjects believed their decision to help would remain anonymous. However, Fultz et al. conducted their experiment decades ago, with few subjects, and before some potentially important cultural changes in college students' values and social lives. Here, in a preregistered replication with 280 undergraduates, we tested Fultz et al.'s key assertions. The perspective-taking and social evaluation manipulations influenced scores on the manipulation check measures mostly in theory-consistent ways but did not significantly influence helping. Consistent with theory, empathy was positively associated with prosocial behavior. We also found evidence that endorsement of the principle of care reflects genuine concern for needy strangers and that moral identity symbolization reflects a desire to help in order to avoid social disapproval. We consider these results a partially successful replication of key tenets of the empathy-altruism hypothesis, though questions remain about the conditions under which perspective-taking promotes prosocial behavior and about the generalizability of our findings to populations beyond undergraduate women circa 1986. Our results also help illuminate the motivational underpinnings of two individual differences that predicted prosocial behavior in previous research. (PsycInfo Database Record (c) 2024 APA, all rights reserved).
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OBJECTIVE: Problem gambling may be an underappreciated treatment target for reducing self-harm. Multivariate studies examining the relationship between problem gambling and self-harm have returned inconsistent results, perhaps due to insufficient power or differences in study quality. METHOD: We conducted a series of meta-analyses examining the effect of problem gambling on self-harm outcomes of varying severity. We assessed the sensitivity of results to study characteristics, publication bias, and influential cases. To highlight threats to causal inference, we evaluated each study for residual confounding bias. RESULTS: In total, two types of meta-analyses were adequately powered: those assessing (a) the effect of problem gambling (binary) on suicide ideation and (b) problem gambling (binary) on suicide attempt (k = 14 unique studies between the two meta-analyses). For both meta-analyses, we found a positive, statistically significant average effect of problem gambling on the respective self-harm outcome. We did not detect any influential studies among these two meta-analyses, nor residual confounding. However, these findings are limited by the overall quality of included literature. PET-PEESE analysis detected substantial potential publication bias in the main results, with both meta-analytic effects being reduced to statistical nonsignificance. All included studies also used a cross-sectional design for their analysis of interest, thus simultaneity bias cannot be ruled out. CONCLUSION: While these findings suggest there is an appreciable relationship between problem gambling and at least two forms of self-harm (suicide ideation and attempts), well-designed longitudinal research is needed to make more firm conclusions. (PsycInfo Database Record (c) 2023 APA, all rights reserved).
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Jogo de Azar , Comportamento Autodestrutivo , Humanos , Jogo de Azar/epidemiologia , Estudos Transversais , Tentativa de Suicídio , Comportamento Autodestrutivo/epidemiologia , Ideação SuicidaRESUMO
OBJECTIVES: Systematic mapping of evaluations of tools and interventions that are intended to mitigate risks for gambling harm. DESIGN: Scoping Review and z-curve analysis (which estimates the average replicability of a body of literature). SEARCH STRATEGY: We searched 7 databases. We also examined reference lists of included studies, as well as papers that cited included studies. Included studies described a quantitative empirical assessment of a game-based (i.e., intrinsic to a specific gambling product) structural feature, user-directed tool, or regulatory initiative to promote responsible gambling. At least two research assistants independently performed screening and extracted study characteristics (e.g., study design and sample size). One author extracted statistics for the z-curve analysis. RESULTS: 86 studies met inclusion criteria. No tools or interventions had unambiguous evidence of efficacy, but some show promise, such as within-session breaks in play. Pre-registration of research hypotheses, methods, and analytic plans was absent until 2019, reflecting a recent embracement of open science practices. Published studies also inconsistently reported effect sizes and power analyses. The results of z-curve provide some evidence of publication bias, and suggest that the replicability of the responsible product design literature is uncertain but could be low. CONCLUSION: Greater transparency and precision are paramount to improving the evidence base for responsible product design to mitigate gambling-related harm.
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Jogo de Azar , Comportamento Aditivo , Bases de Dados Factuais , Jogo de Azar/prevenção & controle , Redução do Dano , HumanosRESUMO
There is a very high suicide rate in the year after psychiatric hospital discharge. Intensive postdischarge case management programs can address this problem but are not cost-effective for all patients. This issue can be addressed by developing a risk model to predict which inpatients might need such a program. We developed such a model for the 391,018 short-term psychiatric hospital admissions of US veterans in Veterans Health Administration (VHA) hospitals 2010-2013. Records were linked with the National Death Index to determine suicide within 12 months of hospital discharge (n=771). The Super Learner ensemble machine learning method was used to predict these suicides for time horizon between 1 week and 12 months after discharge in a 70% training sample. Accuracy was validated in the remaining 30% holdout sample. Predictors included VHA administrative variables and small area geocode data linked to patient home addresses. The models had AUC=.79-.82 for time horizons between 1 week and 6 months and AUC=.74 for 12 months. An analysis of operating characteristics showed that 22.4%-32.2% of patients who died by suicide would have been reached if intensive case management was provided to the 5% of patients with highest predicted suicide risk. Positive predictive value (PPV) at this higher threshold ranged from 1.2% over 12 months to 3.8% per case manager year over 1 week. Focusing on the low end of the risk spectrum, the 40% of patients classified as having lowest risk account for 0%-9.7% of suicides across time horizons. Variable importance analysis shows that 51.1% of model performance is due to psychopathological risk factors accounted, 26.2% to social determinants of health, 14.8% to prior history of suicidal behaviors, and 6.6% to physical disorders. The paper closes with a discussion of next steps in refining the model and prospects for developing a parallel precision treatment model.
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The Social Heuristics Hypothesis claims that cooperation is intuitive because it is positively reinforced in everyday life, where behaviour typically has reputational consequences1,2. Consequently, participants will cooperate in anonymous laboratory settings unless they either reflect on the one-shot nature of the interaction or learn through experience with such settings that cooperation does not promote self-interest. Experiments reveal that cognitive-processing manipulations (which increase reliance on either intuition or deliberation) indeed affect cooperation3, but may also introduce confounds4,5. Here, we elide the interpretation issues created by between-subjects designs in showing that people are less cooperative over time in laboratory paradigms in which cooperation cannot promote self-interest, but are just as cooperative over time in paradigms that have the potential to promote self-interest. Contrary to previous findings6,7, we find that cooperation is equally intuitive for men and women: unilateral giving did not differ across gender at the first study session, and decreased equally for both genders across sessions.
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Comportamento Cooperativo , Relações Interpessoais , Intuição , Altruísmo , Feminino , Jogos Experimentais , Heurística , Humanos , Masculino , Fatores Sexuais , Confiança , Adulto JovemRESUMO
Researchers have identified the capacity to take the perspective of others as a precursor to empathy-induced altruistic motivation. Consequently, investigators frequently use so-called perspective-taking instructions to manipulate empathic concern. However, most experiments using perspective-taking instructions have had modest sample sizes, undermining confidence in the replicability of results. In addition, it is unknown whether perspective-taking instructions work because they increase empathic concern or because comparison conditions reduce empathic concern (or both). Finally, some researchers have found that egoistic factors that do not involve empathic concern, including self-oriented emotions and self-other overlap, mediate the relationship between perspective-taking instructions and helping. The present investigation was a high-powered, preregistered effort that addressed methodological shortcomings of previous experiments to clarify how and when perspective-taking manipulations affect emotional arousal and prosocial motivation in a prototypical experimental paradigm administered over the Internet. Perspective-taking instructions did not clearly increase empathic concern; this null finding was not due to ceiling effects. Instructions to remain objective, on the other hand, unequivocally reduced empathic concern relative to a no-instructions control condition. Empathic concern was the most strongly felt emotion in all conditions, suggesting that distressed targets primarily elicit other-oriented concern. Empathic concern uniquely predicted the quality of social support provided to the target, which supports the empathy-altruism hypothesis and contradicts the role of self-oriented emotions and self-other overlap in explaining helping behavior. Empathy-induced altruism may be responsible for many prosocial acts that occur in everyday settings, including the increasing number of prosocial acts that occur online. (PsycINFO Database Record
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Altruísmo , Emoções/fisiologia , Empatia/fisiologia , Adolescente , Adulto , Feminino , Humanos , Internet , Masculino , Apoio Social , Adulto JovemRESUMO
Many social scientists believe humans possess an evolved motivation to punish violations of norms-including norm violations that do not harm them directly. However, most empirical evidence for so-called altruistic punishment comes from experimental economics games that create experimental demand for third-party punishment, raising the possibility that the third-party punishment uncovered in these experiments has been motivated by a desire to appear concerned about social norms rather than by actual concern about upholding them. Here we present the results of five experiments in which we used an aggression paradigm to contrast second-party and third-party punishment with minimal experimental demand. We also summarize the results of these experiments meta-analytically. We found robust evidence that participants who were insulted by a stranger experienced anger and punished the insulter. To a lesser degree, participants who witnessed a friend receive an insult also became angry and punished the insulter. In contrast, we found robust evidence that participants who witnessed a stranger receive an insult did not punish the insulter, although they did experience modest amounts of anger. In only one experiment did we find any punishment on behalf of a stranger, and this result could plausibly be explained by the desire to escape the moral censure of other bystanders. Our results suggest that experimental designs that rely on demand-laden methods to test hypotheses about third-party punishment may have overstated the case for the existence of this trait. (PsycINFO Database Record