Detalhe da pesquisa
1.
Reduction in ocular complement factor B protein in mice and monkeys by systemic administration of factor B antisense oligonucleotide.
Mol Vis
; 23: 561-571, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28855795
2.
In vivo reduction of hepatitis B virus antigenemia and viremia by antisense oligonucleotides.
J Hepatol
; 64(4): 781-9, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-26658683
3.
TMPRSS6 as a Therapeutic Target for Disorders of Erythropoiesis and Iron Homeostasis.
Adv Ther
; 40(4): 1317-1333, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36690839
4.
IL-4 Receptor Alpha Signaling through Macrophages Differentially Regulates Liver Fibrosis Progression and Reversal.
EBioMedicine
; 29: 92-103, 2018 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-29463471
5.
Inhibition of the alternative complement pathway by antisense oligonucleotides targeting complement factor B improves lupus nephritis in mice.
Immunobiology
; 221(6): 701-8, 2016 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-26307001
6.
Allele-Specific Inhibition of Rhodopsin With an Antisense Oligonucleotide Slows Photoreceptor Cell Degeneration.
Invest Ophthalmol Vis Sci
; 56(11): 6362-75, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26436889
7.
Clinical Trial Design for Alpha-1 Antitrypsin Deficiency: A Model for Rare Diseases.
Chronic Obstr Pulm Dis
; 2(2): 177-190, 2015 Apr 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-28848840
8.
Using antisense technology to develop a novel therapy for α-1 antitrypsin deficient (AATD) liver disease and to model AATD lung disease.
Rare Dis
; 2: e28511, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-25054094
9.
Antisense oligonucleotide treatment ameliorates alpha-1 antitrypsin-related liver disease in mice.
J Clin Invest
; 124(1): 251-61, 2014 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-24355919
10.
Peripheral reduction of FGFR4 with antisense oligonucleotides increases metabolic rate and lowers adiposity in diet-induced obese mice.
PLoS One
; 8(7): e66923, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23922646