RESUMO
Defined formula diets, shown to be clinically effective in separate trials, have never been compared in the same subjects under identical controls. The intent of this study was to determine which one of three diets, (Vivonex, Flexical, or Precision LR) was most effectively absorbed and utilized. Stool weight and frequency, nitrogen balance and fecal fat, ash and moisture were measured. In addition, subjective comments were recorded regarding overall acceptability and ease of preparation. Statistically significant differences were found only in total stool weight. The data imply that the underlying disease state of the patient, the individual's response to the diet, the composition, cost, availability, and storage requirements of the diet must be taken into consideration when selecting a low residue formulation.
Assuntos
Dieta/normas , Fezes , Nitrogênio/metabolismo , Adolescente , Adulto , Defecação , Carboidratos da Dieta/análise , Gorduras na Dieta/análise , Fezes/análise , Feminino , Análise de Alimentos , Gastroenteropatias/dietoterapia , Humanos , Lipídeos/análise , Masculino , Pessoa de Meia-Idade , Minerais/análise , Nitrogênio/análiseRESUMO
Chronic depletion of body chloride developed in a group of infants ingesting a diet consisting almost exclusively of chloride deficient Neo-Mull-Soy. Ten of the 12 infants were on this diet three to five months before loss of appetite, failure to thrive, muscle weakness, and lethargy led to a diagnostic evaluation. The outstanding laboratory features were severe hypokalemic metabolic alkalosis, low urinary chloride concentrations (< 10 mEq/liter), and erythrocyturia. There was marked decrease in weight for age in all 12 infants. Head circumference for age had decreased in five of six and length for age in five of ten infants for whom earlier measurements were available. The biochemical abnormalities reverted to normal following dietary supplementation with either sodium or potassium chloride. Appetite, affect, and muscle strength improved, and weight gain resumed. Head circumference for age has moved toward the percentile level present prior to starting Neo-Mull-Soy in all instances. With one exception, length measurements show a similar pattern. The erythrocyturia has decreased or vanished. Chloride deficiency led to contraction of the extracellular volume and the substitution of poorly reabsorbable anions for readily reabsorbable chloride. These alterations caused development of the negative hydrogen ion and potassium balances which led to the hypokalemic metabolic alkalosis.