RESUMO
Cardiac amyloidosis is an infiltrative abnormality that causes myocardial thickening and dysfunction. Historically, it has been underrecognized as a cause of heart failure and was often misdiagnosed. In the past decade, the cardiology community has improved the understanding of the subtypes of these protein-based infiltrates and how they play a role in heart failure. This article reviews the pathophysiology, presentation, diagnosis, and management of cardiac amyloidosis.
Assuntos
Amiloidose/diagnóstico , Amiloidose/terapia , Cardiomiopatias/diagnóstico , Cardiomiopatias/terapia , Neuropatias Amiloides Familiares , Amiloidose/etiologia , Amiloidose/patologia , Cardiomiopatias/etiologia , Cardiomiopatias/patologia , Diagnóstico Diferencial , Erros de Diagnóstico/prevenção & controle , Ecocardiografia , Insuficiência Cardíaca/etiologia , Humanos , Cadeias Leves de Imunoglobulina , Amiloidose de Cadeia Leve de Imunoglobulina , Miocárdio/patologia , Pré-AlbuminaAssuntos
Insuficiência Cardíaca/diagnóstico , Antagonistas Adrenérgicos beta/uso terapêutico , Adulto , Bloqueio de Ramo , Tosse/etiologia , Diagnóstico Diferencial , Dispneia/etiologia , Ecocardiografia , Eletrocardiografia , Feminino , Furosemida/uso terapêutico , Insuficiência Cardíaca/complicações , Insuficiência Cardíaca/tratamento farmacológico , Humanos , Antagonistas de Receptores de Mineralocorticoides/uso terapêutico , Insuficiência da Valva Mitral , Recidiva , Infecções Respiratórias/diagnóstico , Inibidores de Simportadores de Cloreto de Sódio e Potássio/uso terapêutico , Volume SistólicoRESUMO
Heart failure (HF) is a significant clinical and financial burden worldwide. Remote monitoring (RM) devices capable of identifying early physiologic changes in decompensation have the potential to reduce the HF burden. However, few trials have discussed at length the practical aspects of implementing RM in real-world clinical practice. The present paper reviews current RM devices and clinical trials, focusing on patient populations, outcomes, data collection, storage, and management, and describes the implementation of an RM device in clinical practice, providing a pragmatic and adaptable framework.