Detalhe da pesquisa
1.
IPSC-Derived Astrocytes Contribute to In Vitro Modeling of Parkinson's Disease Caused by the GBA1 N370S Mutation.
Int J Mol Sci
; 25(1)2023 Dec 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-38203497
2.
Transcriptomic Analysis of CRISPR/Cas9-Mediated PARP1-Knockout Cells under the Influence of Topotecan and TDP1 Inhibitor.
Int J Mol Sci
; 24(6)2023 Mar 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-36982223
3.
Biochemical Characteristics of iPSC-Derived Dopaminergic Neurons from N370S GBA Variant Carriers with and without Parkinson's Disease.
Int J Mol Sci
; 24(5)2023 Feb 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-36901867
4.
New Hybrid Compounds Combining Fragments of Usnic Acid and Thioether Are Inhibitors of Human Enzymes TDP1, TDP2 and PARP1.
Int J Mol Sci
; 22(21)2021 Oct 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-34768766
5.
Design, Synthesis, and Biological Investigation of Novel Classes of 3-Carene-Derived Potent Inhibitors of TDP1.
Molecules
; 25(15)2020 Jul 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-32751997
6.
Impact of Xist RNA on chromatin modifications and transcriptional silencing maintenance at different stages of imprinted X chromosome inactivation in vole Microtus levis.
Chromosoma
; 127(1): 129-139, 2018 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29151149
7.
A Knockout of Poly(ADP-Ribose) Polymerase 1 in a Human Cell Line: An Influence on Base Excision Repair Reactions in Cellular Extracts.
Cells
; 13(4)2024 Feb 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-38391916
8.
Detection of ER Stress in iPSC-Derived Neurons Carrying the p.N370S Mutation in the GBA1 Gene.
Biomedicines
; 12(4)2024 Mar 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-38672099
9.
Transcriptomic analysis of HEK293A cells with a CRISPR/Cas9-mediated TDP1 knockout.
Biochim Biophys Acta Gen Subj
; 1868(7): 130616, 2024 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-38621596
10.
Usnic Acid Derivatives Inhibit DNA Repair Enzymes Tyrosyl-DNA Phosphodiesterases 1 and 2 and Act as Potential Anticancer Agents.
Genes (Basel)
; 14(10)2023 10 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37895279
11.
Oxidative stress monitoring in iPSC-derived motor neurons using genetically encoded biosensors of H2O2.
Sci Rep
; 12(1): 8928, 2022 05 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-35624228
12.
Generation of induced pluripotent stem cell line, ICGi034-A, by reprogramming peripheral blood mononuclear cells from a patient with Parkinson's disease associated with GBA mutation.
Stem Cell Res
; 59: 102651, 2022 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-35007918
13.
Genetically Encoded Fluorescent Biosensors for Biomedical Applications.
Biomedicines
; 9(11)2021 Oct 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-34829757
14.
The Cutting Edge of Disease Modeling: Synergy of Induced Pluripotent Stem Cell Technology and Genetically Encoded Biosensors.
Biomedicines
; 9(8)2021 Aug 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-34440164
15.
Mild phenotype of knockouts of the major apurinic/apyrimidinic endonuclease APEX1 in a non-cancer human cell line.
PLoS One
; 16(9): e0257473, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34529719
16.
New Hybrid Compounds Combining Fragments of Usnic Acid and Monoterpenoids for Effective Tyrosyl-DNA Phosphodiesterase 1 Inhibition.
Biomolecules
; 11(7)2021 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34356597
17.
Comparative Metabolomic Profiling of Rat Embryonic and Induced Pluripotent Stem Cells.
Stem Cell Rev Rep
; 16(6): 1256-1265, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33047280
18.
Structure and expression pattern of Oct4 gene are conserved in vole Microtus rossiaemeridionalis.
BMC Genomics
; 9: 162, 2008 Apr 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-18402712
19.
Noncoding RNAs in the Regulation of Pluripotency and Reprogramming.
Stem Cell Rev Rep
; 14(1): 58-70, 2018 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-29143182
20.
Modern Genome Editing Technologies in Huntington's Disease Research.
J Huntingtons Dis
; 6(1): 19-31, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28128770