RESUMO
Squamous cell carcinoma (SCC) of the colon is a rare tumor that accounts for 0.1%-0.2% of colonic malignancies. However, pure SCC of the cecum is extremely rare. Although SCC of the colon is a rare complication of idiopathic inflammatory bowel disease (IBD), SCC of the cecum in the context of IBD has not been previously reported in the English literature. We report a case of the coexistence of SCC of the cecum and a carcinoid tumor in a 46-year-old female with long-standing pan-ulcerative colitis.
Assuntos
Apêndice , Tumor Carcinoide/etiologia , Neoplasias do Ceco/etiologia , Colite Ulcerativa/complicações , Biópsia , Tumor Carcinoide/diagnóstico , Tumor Carcinoide/cirurgia , Neoplasias do Ceco/diagnóstico , Neoplasias do Ceco/cirurgia , Colectomia/métodos , Colonoscopia , Diagnóstico Diferencial , Feminino , Humanos , Pessoa de Meia-Idade , Tomografia Computadorizada por Raios XRESUMO
A 48-year-old woman presented with a 2-week history of diarrhoea and abdominal pain. No overt gastrointestinal bleeding was reported and there was no history of loss of weight or loss of appetite. General and abdominal examination was unremarkable except for subconjunctival pallor. The haemoglobin was 7.1 g/dl at presentation with the peripheral blood film indicating iron deficiency anaemia. An urgent colonoscopy revealed two strictures within a 5 cm segment of transverse colon. The distal stricture showed significant ulceration and inflammation, while the proximal one showed an impassable "diaphragm-like" stricture. Biopsies from both of the strictures showed chronic inflammatory infiltrate with numerous eosinophils and no evidence of malignancy. The patient had been taking enteric-coated diclofenac tablets 50 mg three times daily over the past 10 years for chronic backache. Her bowel symptoms resolved significantly within 4 weeks of stopping diclofenac and she continued to remain relatively asymptomatic at 3 months follow-up.
Assuntos
Neoplasias do Colo/diagnóstico , Sangue Oculto , Idoso , Reações Falso-Negativas , Feminino , Humanos , Masculino , Pessoa de Meia-IdadeRESUMO
Small-bowel adenocarcinoma is an uncommon tumor, comprising<2 percent of all gastrointestinal tract malignancies. These tumors are known to occur in association with Crohn's disease. To date, there have been only two documented cases of adenocarcinoma arising at the site of previous strictureplasty reported in the literature. We report the third such case in a patient with no other premalignant conditions affecting the small bowel and question whether we may see an increasing trend in this type of presentation.