Pesquisa | Portal de Pesquisa da BVS Enfermagem

1.

A cholesterol switch controls phospholipid scrambling by G protein-coupled receptors.

Menon, Indu; Sych, Taras; Son, Yeeun; Morizumi, Takefumi; Lee, Joon; Ernst, Oliver P; Khelashvili, George; Sezgin, Erdinc; Levitz, Joshua; Menon, Anant K.

J Biol Chem ; 300(2): 105649, 2024 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-38237683

2.

Genome-wide CRISPR screen reveals CLPTM1L as a lipid scramblase required for efficient glycosylphosphatidylinositol biosynthesis.

Wang, Yicheng; Menon, Anant K; Maki, Yuta; Liu, Yi-Shi; Iwasaki, Yugo; Fujita, Morihisa; Guerrero, Paula A; Silva, Daniel Varó'n; Seeberger, Peter H; Murakami, Yoshiko; Kinoshita, Taroh.

Proc Natl Acad Sci U S A ; 119(14): e2115083119, 2022 04 05.

Artigo em Inglês | MEDLINE | ID: mdl-35344438

3.

Rethinking Opsins.

Feuda, Roberto; Menon, Anant K; Göpfert, Martin C.

Mol Biol Evol ; 39(3)2022 03 02.

Artigo em Inglês | MEDLINE | ID: mdl-35143663

4.

Identification of TbPBN1 in Trypanosoma brucei reveals a conserved heterodimeric architecture for glycosylphosphatidylinositol-mannosyltransferase-I.

Cowton, Andrew; Bütikofer, Peter; Häner, Robert; Menon, Anant K.

Mol Microbiol ; 117(2): 450-461, 2022 02.

Artigo em Inglês | MEDLINE | ID: mdl-34875117

5.

Elimination of GPI2 suppresses glycosylphosphatidylinositol GlcNAc transferase activity and alters GPI glycan modification in Trypanosoma brucei.

Jenni, Aurelio; Knüsel, Sebastian; Nagar, Rupa; Benninger, Mattias; Häner, Robert; Ferguson, Michael A J; Roditi, Isabel; Menon, Anant K; Bütikofer, Peter.

J Biol Chem ; 297(2): 100977, 2021 08.

Artigo em Inglês | MEDLINE | ID: mdl-34284059

6.

Speed Limits for Nonvesicular Intracellular Sterol Transport.

Dittman, Jeremy S; Menon, Anant K.

Trends Biochem Sci ; 42(2): 90-97, 2017 02.

Artigo em Inglês | MEDLINE | ID: mdl-27956059

7.

Endoplasmic reticulum-plasma membrane contact sites integrate sterol and phospholipid regulation.

Quon, Evan; Sere, Yves Y; Chauhan, Neha; Johansen, Jesper; Sullivan, David P; Dittman, Jeremy S; Rice, William J; Chan, Robin B; Di Paolo, Gilbert; Beh, Christopher T; Menon, Anant K.

PLoS Biol ; 16(5): e2003864, 2018 05.

Artigo em Inglês | MEDLINE | ID: mdl-29782498

8.

Out-of-the-groove transport of lipids by TMEM16 and GPCR scramblases.

Malvezzi, Mattia; Andra, Kiran K; Pandey, Kalpana; Lee, Byoung-Cheol; Falzone, Maria E; Brown, Ashley; Iqbal, Rabia; Menon, Anant K; Accardi, Alessio.

Proc Natl Acad Sci U S A ; 115(30): E7033-E7042, 2018 07 24.

Artigo em Inglês | MEDLINE | ID: mdl-29925604

9.

Ergosterol is mainly located in the cytoplasmic leaflet of the yeast plasma membrane.

Solanko, Lukasz M; Sullivan, David P; Sere, Yves Y; Szomek, Maria; Lunding, Anita; Solanko, Katarzyna A; Pizovic, Azra; Stanchev, Lyubomir D; Pomorski, Thomas Günther; Menon, Anant K; Wüstner, Daniel.

Traffic ; 19(3): 198-214, 2018 03.

Artigo em Inglês | MEDLINE | ID: mdl-29282820

10.

A PhotoClick cholesterol-based quantitative proteomics screen for cytoplasmic sterol-binding proteins in Saccharomyces cerevisiae.

Chauhan, Neha; Sere, Yves Y; Sokol, Anna M; Graumann, Johannes; Menon, Anant K.

Yeast ; 37(1): 15-25, 2020 01.

Artigo em Inglês | MEDLINE | ID: mdl-31758572

11.

Lipid landscapes and pipelines in membrane homeostasis.

Holthuis, Joost C M; Menon, Anant K.

Nature ; 510(7503): 48-57, 2014 Jun 05.

Artigo em Inglês | MEDLINE | ID: mdl-24899304

12.

Nonenzymatic synthesis of anomerically pure, mannosyl-based molecular probes for scramblase identification studies.

Picca, Giovanni; Probst, Markus; Langenegger, Simon M; Khorev, Oleg; Bütikofer, Peter; Menon, Anant K; Häner, Robert.

Beilstein J Org Chem ; 16: 1732-1739, 2020.

Artigo em Inglês | MEDLINE | ID: mdl-32765793

13.

Structural mapping of fluorescently-tagged, functional nhTMEM16 scramblase in a lipid bilayer.

Andra, Kiran K; Dorsey, Savanna; Royer, Catherine A; Menon, Anant K.

J Biol Chem ; 293(31): 12248-12258, 2018 08 03.

Artigo em Inglês | MEDLINE | ID: mdl-29903908

14.

Scrambling of natural and fluorescently tagged phosphatidylinositol by reconstituted G protein-coupled receptor and TMEM16 scramblases.

Wang, Lei; Iwasaki, Yugo; Andra, Kiran K; Pandey, Kalpana; Menon, Anant K; Bütikofer, Peter.

J Biol Chem ; 293(47): 18318-18327, 2018 11 23.

Artigo em Inglês | MEDLINE | ID: mdl-30287690

15.

Structural basis of sterol binding and transport by a yeast StARkin domain.

Jentsch, Julian-Alexander; Kiburu, Irene; Pandey, Kalpana; Timme, Michael; Ramlall, Trudy; Levkau, Bodo; Wu, Jin; Eliezer, David; Boudker, Olga; Menon, Anant K.

J Biol Chem ; 293(15): 5522-5531, 2018 04 13.

Artigo em Inglês | MEDLINE | ID: mdl-29463678

16.

RFT1 Protein Affects Glycosylphosphatidylinositol (GPI) Anchor Glycosylation.

Gottier, Petra; Gonzalez-Salgado, Amaia; Menon, Anant K; Liu, Yuk-Chien; Acosta-Serrano, Alvaro; Bütikofer, Peter.

J Biol Chem ; 292(3): 1103-1111, 2017 01 20.

Artigo em Inglês | MEDLINE | ID: mdl-27927990

17.

flippant-An R package for the automated analysis of fluorescence-based scramblase assays.

Cotton, Richard J; Ploier, Birgit; Goren, Michael A; Menon, Anant K; Graumann, Johannes.

BMC Bioinformatics ; 18(1): 146, 2017 Mar 03.

Artigo em Inglês | MEDLINE | ID: mdl-28253836

18.

Lipid topogenesis--35years on.

Chauhan, Neha; Farine, Luce; Pandey, Kalpana; Menon, Anant K; Bütikofer, Peter.

Biochim Biophys Acta ; 1861(8 Pt B): 757-766, 2016 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-26946259

19.

The nhTMEM16 Scramblase Is Also a Nonselective Ion Channel.

Lee, Byoung-Cheol; Menon, Anant K; Accardi, Alessio.

Biophys J ; 111(9): 1919-1924, 2016 Nov 01.

Artigo em Inglês | MEDLINE | ID: mdl-27806273

20.

Structural biology: Lipid gymnastics.

Verchère, Alice; Menon, Anant K.

Nature ; 524(7566): 420-2, 2015 Aug 27.

Artigo em Inglês | MEDLINE | ID: mdl-26266983

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