Detalhe da pesquisa
1.
Dysregulated expression of cholesterol biosynthetic genes in Alzheimer's disease alters epigenomic signatures of hippocampal neurons.
Neurobiol Dis
; 198: 106538, 2024 May 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-38789057
2.
Epigenetic mechanisms underlying enhancer modulation of neuronal identity, neuronal activity and neurodegeneration.
Neurobiol Dis
; 147: 105155, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33127472
3.
Myelinosome Organelles in the Retina of R6/1 Huntington Disease (HD) Mice: Ubiquitous Distribution and Possible Role in Disease Spreading.
Int J Mol Sci
; 22(23)2021 Nov 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-34884576
4.
The striatal kinase DCLK3 produces neuroprotection against mutant huntingtin.
Brain
; 141(5): 1434-1454, 2018 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29534157
5.
Neuronal identity genes regulated by super-enhancers are preferentially down-regulated in the striatum of Huntington's disease mice.
Hum Mol Genet
; 24(12): 3481-96, 2015 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25784504
6.
What is gained or 'lost in translation' in Huntington's disease.
Brain
; 142(10): 2900-2902, 2019 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31560061
7.
Transcription elongation and tissue-specific somatic CAG instability.
PLoS Genet
; 8(11): e1003051, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-23209427
8.
Mutant FUS induces chromatin reorganization in the hippocampus and alters memory processes.
Prog Neurobiol
; 227: 102483, 2023 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-37327984
9.
The nucleotide sequence, DNA damage location, and protein stoichiometry influence the base excision repair outcome at CAG/CTG repeats.
Biochemistry
; 51(18): 3919-32, 2012 May 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-22497302
10.
Stoichiometry of base excision repair proteins correlates with increased somatic CAG instability in striatum over cerebellum in Huntington's disease transgenic mice.
PLoS Genet
; 5(12): e1000749, 2009 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-19997493
11.
Hippocampal Cannabinoid 1 Receptors Are Modulated Following Cocaine Self-administration in Male Rats.
Mol Neurobiol
; 59(3): 1896-1911, 2022 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-35032317
12.
Altered activity-regulated H3K9 acetylation at TGF-beta signaling genes during egocentric memory in Huntington's disease.
Prog Neurobiol
; 219: 102363, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36179935
13.
Age-related and disease locus-specific mechanisms contribute to early remodelling of chromatin structure in Huntington's disease mice.
Nat Commun
; 12(1): 364, 2021 01 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-33441541
14.
Mitogen- and stress-activated protein kinase-1 deficiency is involved in expanded-huntingtin-induced transcriptional dysregulation and striatal death.
FASEB J
; 22(4): 1083-93, 2008 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-18029446
15.
Neuroepigenetics and addictive behaviors: Where do we stand?
Neurosci Biobehav Rev
; 106: 58-72, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30205119
16.
Cell-Type-Specific Gene Expression Profiling in Adult Mouse Brain Reveals Normal and Disease-State Signatures.
Cell Rep
; 26(9): 2477-2493.e9, 2019 02 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-30811995
17.
Reinstating plasticity and memory in a tauopathy mouse model with an acetyltransferase activator.
EMBO Mol Med
; 10(11)2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30275019
18.
SCA8 CAG/CTG expansions, a tale of two TOXICities: a unique or common case?
PLoS Genet
; 5(8): e1000593, 2009 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-19680445
19.
Contribution of Neuroepigenetics to Huntington's Disease.
Front Hum Neurosci
; 11: 17, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28194101
20.
Altered enhancer transcription underlies Huntington's disease striatal transcriptional signature.
Sci Rep
; 7: 42875, 2017 02 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-28225006