Detalhe da pesquisa
1.
Oligopeptide Signaling through TbGPR89 Drives Trypanosome Quorum Sensing.
Cell
; 176(1-2): 306-317.e16, 2019 01 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30503212
2.
L-plastin associated syndrome of immune deficiency and hematologic cytopenia.
J Allergy Clin Immunol
; 2024 May 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-38710235
3.
Antileishmanial Activities of (Z)-2-(Nitroimidazolylmethylene)-3(2H)-Benzofuranones: Synthesis, In Vitro Assessment, and Bioactivation by NTR 1 and 2.
Antimicrob Agents Chemother
; 66(11): e0058322, 2022 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36286539
4.
High-Throughput Screening Platform To Identify Inhibitors of Protein Synthesis with Potential for the Treatment of Malaria.
Antimicrob Agents Chemother
; 66(6): e0023722, 2022 06 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-35647647
5.
Identification of a Proteasome-Targeting Arylsulfonamide with Potential for the Treatment of Chagas' Disease.
Antimicrob Agents Chemother
; 66(1): e0153521, 2022 01 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-34606338
6.
Chemical pulldown combined with mass spectrometry to identify the molecular targets of antimalarials in cell-free lysates.
STAR Protoc
; 4(1): 102002, 2023 03 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-36609153
7.
Potent acyl-CoA synthetase 10 inhibitors kill Plasmodium falciparum by disrupting triglyceride formation.
Nat Commun
; 14(1): 1455, 2023 03 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-36927839
8.
Toolkit of Approaches To Support Target-Focused Drug Discovery for Plasmodium falciparum Lysyl tRNA Synthetase.
ACS Infect Dis
; 8(9): 1962-1974, 2022 09 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36037410
9.
Repositioning of a Diaminothiazole Series Confirmed to Target the Cyclin-Dependent Kinase CRK12 for Use in the Treatment of African Animal Trypanosomiasis.
J Med Chem
; 65(7): 5606-5624, 2022 04 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-35303411
10.
Identification and optimisation of novel sulfonamide, selective vasopressin V1B receptor antagonists.
Bioorg Med Chem Lett
; 21(12): 3603-7, 2011 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21601454
11.
Optimisation of pharmacokinetic properties to afford an orally bioavailable and selective V1A receptor antagonist.
Bioorg Med Chem Lett
; 21(15): 4622-8, 2011 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21700453
12.
Synthesis and SAR studies of novel 2-(6-aminomethylaryl-2-aryl-4-oxo-quinazolin-3(4H)-yl)acetamide vasopressin V1b receptor antagonists.
Bioorg Med Chem Lett
; 21(12): 3813-7, 2011 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21596563
13.
The discovery of novel 8-azabicyclo[3.2.1]octan-3-yl)-3-(4-chlorophenyl) propanamides as vasopressin V1A receptor antagonists.
Bioorg Med Chem Lett
; 21(10): 3163-7, 2011 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21458261
14.
Synthesis and SAR studies of novel 2-(4-oxo-2-aryl-quinazolin-3(4H)-yl)acetamide vasopressin V1b receptor antagonists.
Bioorg Med Chem Lett
; 21(6): 1871-5, 2011 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21353540
15.
An enhanced toolkit for the generation of knockout and marker-free fluorescent Plasmodium chabaudi.
Wellcome Open Res
; 5: 71, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32500098
16.
New 8-Nitroquinolinone Derivative Displaying Submicromolar in Vitro Activities against Both Trypanosoma brucei and cruzi.
ACS Med Chem Lett
; 11(4): 464-472, 2020 Apr 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32292551
17.
The Qi Site of Cytochrome b is a Promiscuous Drug Target in Trypanosoma cruzi and Leishmania donovani.
ACS Infect Dis
; 6(3): 515-528, 2020 03 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-31967783
18.
Nongenotoxic 3-Nitroimidazo[1,2-a]pyridines Are NTR1 Substrates That Display Potent in Vitro Antileishmanial Activity.
ACS Med Chem Lett
; 10(1): 34-39, 2019 Jan 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30655943
19.
Immobilization of Irpex lacteus to liquid-core alginate beads and their application to degradation of pollutants.
Folia Microbiol (Praha)
; 62(4): 335-342, 2017 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-28213748
20.
Tumorigenic fragments of APC cause dominant defects in directional cell migration in multiple model systems.
Dis Model Mech
; 5(6): 940-7, 2012 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-22563063