Detalhe da pesquisa
1.
Inherited myeloproliferative neoplasm risk affects haematopoietic stem cells.
Nature
; 586(7831): 769-775, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33057200
2.
Reverting the molecular fingerprint of tumor dormancy as a therapeutic strategy for glioblastoma.
FASEB J
; : fj201701568R, 2018 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29856660
3.
DNA-damage response in hematopoietic stem cells: an evolutionary trade-off between blood regeneration and leukemia suppression.
Carcinogenesis
; 38(4): 367-377, 2017 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28334174
4.
Quercetin alters the DNA damage response in human hematopoietic stem and progenitor cells via TopoII- and PI3K-dependent mechanisms synergizing in leukemogenic rearrangements.
Int J Cancer
; 140(4): 864-876, 2017 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27813122
5.
Lnk adaptor suppresses radiation resistance and radiation-induced B-cell malignancies by inhibiting IL-11 signaling.
Proc Natl Acad Sci U S A
; 110(51): 20599-604, 2013 Dec 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-24297922
6.
Inactivation of myocardin and p16 during malignant transformation contributes to a differentiation defect.
Cancer Cell
; 11(2): 133-46, 2007 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-17292825
7.
Essential role for Ptpn11 in survival of hematopoietic stem and progenitor cells.
Blood
; 117(16): 4253-61, 2011 Apr 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-21398220
8.
T Cells Expressing a Modified FcγRI Exert Antibody-Dependent Cytotoxicity and Overcome the Limitations of CAR T-cell Therapy against Solid Tumors.
Cancer Immunol Res
; 11(6): 792-809, 2023 06 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-37070661
9.
KDM6 demethylases integrate DNA repair gene regulation and loss of KDM6A sensitizes human acute myeloid leukemia to PARP and BCL2 inhibition.
Leukemia
; 37(4): 751-764, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36720973
10.
The NCOR-HDAC3 co-repressive complex modulates the leukemogenic potential of the transcription factor ERG.
Nat Commun
; 14(1): 5871, 2023 09 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-37735473
11.
Sex-specific differences in DNA double-strand break repair of cycling human lymphocytes during aging.
Aging (Albany NY)
; 13(17): 21066-21089, 2021 09 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34506302
12.
Recurrent deletions in clonal hematopoiesis are driven by microhomology-mediated end joining.
Nat Commun
; 12(1): 2455, 2021 04 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-33911081
13.
The mTOR inhibitor everolimus overcomes CXCR4-mediated resistance to histone deacetylase inhibitor panobinostat through inhibition of p21 and mitotic regulators.
Biochem Pharmacol
; 168: 412-428, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31325448
14.
Spironolactone inhibits the growth of cancer stem cells by impairing DNA damage response.
Oncogene
; 38(17): 3103-3118, 2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30622338
15.
A novel method for detecting the cellular stemness state in normal and leukemic human hematopoietic cells can predict disease outcome and drug sensitivity.
Leukemia
; 33(8): 2061-2077, 2019 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-30705411
16.
An ERG Enhancer-Based Reporter Identifies Leukemia Cells with Elevated Leukemogenic Potential Driven by ERG-USP9X Feed-Forward Regulation.
Cancer Res
; 79(15): 3862-3876, 2019 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31175119
17.
Element-tagged immunoassay with ICP-MS detection: evaluation and comparison to conventional immunoassays.
J Immunol Methods
; 336(1): 56-63, 2008 Jul 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-18456275
18.
hTERT-immortalized prostate epithelial and stromal-derived cells: an authentic in vitro model for differentiation and carcinogenesis.
Cancer Res
; 66(7): 3531-40, 2006 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16585177
19.
Mutant p53 protects cells from 12-O-tetradecanoylphorbol-13-acetate-induced death by attenuating activating transcription factor 3 induction.
Cancer Res
; 66(22): 10750-9, 2006 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-17108111
20.
Replication stress in hematopoietic stem cells in mouse and man.
Mutat Res
; 808: 74-82, 2018 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29079268