Detalhe da pesquisa
1.
Sildenafil increases chemotherapeutic efficacy of doxorubicin in prostate cancer and ameliorates cardiac dysfunction.
Proc Natl Acad Sci U S A
; 107(42): 18202-7, 2010 Oct 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-20884855
2.
Multiple cyclin kinase inhibitors promote bile acid-induced apoptosis and autophagy in primary hepatocytes via p53-CD95-dependent signaling.
J Biol Chem
; 291(39): 20823, 2016 09 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-27664064
3.
A serotype 5/3 adenovirus expressing MDA-7/IL-24 infects renal carcinoma cells and promotes toxicity of agents that increase ROS and ceramide levels.
Mol Pharmacol
; 79(3): 368-80, 2011 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-21119025
4.
Poly(ADP-ribose) polymerase 1 modulates the lethality of CHK1 inhibitors in carcinoma cells.
Mol Pharmacol
; 78(5): 909-17, 2010 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-20696794
5.
BCL-2 family inhibitors enhance histone deacetylase inhibitor and sorafenib lethality via autophagy and overcome blockade of the extrinsic pathway to facilitate killing.
Mol Pharmacol
; 76(2): 327-41, 2009 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-19483105
6.
Sorafenib and vorinostat kill colon cancer cells by CD95-dependent and -independent mechanisms.
Mol Pharmacol
; 76(2): 342-55, 2009 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-19483104
7.
Vorinostat and sorafenib synergistically kill tumor cells via FLIP suppression and CD95 activation.
Clin Cancer Res
; 14(17): 5385-99, 2008 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-18765530
8.
Transient exposure of carcinoma cells to RAS/MEK inhibitors and UCN-01 causes cell death in vitro and in vivo.
Mol Cancer Ther
; 7(3): 616-29, 2008 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-18347148
9.
Mitogen-activated protein kinase kinase 1/2 inhibitors and 17-allylamino-17-demethoxygeldanamycin synergize to kill human gastrointestinal tumor cells in vitro via suppression of c-FLIP-s levels and activation of CD95.
Mol Cancer Ther
; 7(9): 2633-48, 2008 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-18790746
10.
Lapatinib resistance in HCT116 cells is mediated by elevated MCL-1 expression and decreased BAK activation and not by ERBB receptor kinase mutation.
Mol Pharmacol
; 74(3): 807-22, 2008 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-18544666
11.
Extrinsic pathway- and cathepsin-dependent induction of mitochondrial dysfunction are essential for synergistic flavopiridol and vorinostat lethality in breast cancer cells.
Mol Cancer Ther
; 6(12 Pt 1): 3101-12, 2007 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-18065490
12.
17-Allylamino-17-demethoxygeldanamycin enhances the lethality of deoxycholic acid in primary rodent hepatocytes and established cell lines.
Mol Cancer Ther
; 6(2): 618-32, 2007 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-17308059
13.
H-RAS V12-induced radioresistance in HCT116 colon carcinoma cells is heregulin dependent.
Mol Cancer Ther
; 4(2): 243-55, 2005 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-15713896
14.
Activated forms of H-RAS and K-RAS differentially regulate membrane association of PI3K, PDK-1, and AKT and the effect of therapeutic kinase inhibitors on cell survival.
Mol Cancer Ther
; 4(2): 257-70, 2005 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-15713897
15.
Sildenafil (Viagra) sensitizes prostate cancer cells to doxorubicin-mediated apoptosis through CD95.
Oncotarget
; 7(4): 4399-413, 2016 Jan 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-26716643
16.
Transient exposure of mammary tumors to PD184352 and UCN-01 causes tumor cell death in vivo and prolonged suppression of tumor regrowth.
Cancer Biol Ther
; 4(11): 1275-84, 2005 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-16319524
17.
Inhibition of insulin/IGF-1 receptor signaling enhances bile acid toxicity in primary hepatocytes.
Biochem Pharmacol
; 70(11): 1685-96, 2005 Nov 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-16207485
18.
Melanoma differentiation-associated 7 (interleukin 24) inhibits growth and enhances radiosensitivity of glioma cells in vitro and in vivo.
Clin Cancer Res
; 9(9): 3272-81, 2003 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-12960112
19.
MDA-7 (interleukin-24) inhibits the proliferation of renal carcinoma cells and interacts with free radicals to promote cell death and loss of reproductive capacity.
Mol Cancer Ther
; 2(7): 623-32, 2003 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-12883035
20.
mda-7 (IL-24) Inhibits growth and enhances radiosensitivity of glioma cells in vitro via JNK signaling.
Cancer Biol Ther
; 2(4): 347-53, 2003.
Artigo
em Inglês
| MEDLINE | ID: mdl-14508103