Detalhe da pesquisa
1.
A Zn-dependent structural transition of SOD1 modulates its ability to undergo phase separation.
EMBO J
; 42(2): e111185, 2023 01 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-36416085
2.
Mechanistic View of hnRNPA2 Low-Complexity Domain Structure, Interactions, and Phase Separation Altered by Mutation and Arginine Methylation.
Mol Cell
; 69(3): 465-479.e7, 2018 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29358076
3.
A synergy between site-specific and transient interactions drives the phase separation of a disordered, low-complexity domain.
Proc Natl Acad Sci U S A
; 120(34): e2305625120, 2023 08 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-37579155
4.
Regulating phase behavior of nanoparticle assemblies through engineering of DNA-mediated isotropic interactions.
Proc Natl Acad Sci U S A
; 120(52): e2302037120, 2023 Dec 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-38109548
5.
Specific residues and conformational plasticity define the substrate specificity of short-chain dehydrogenases/reductases.
J Biol Chem
; 300(1): 105596, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-38145745
6.
Tyrosine phosphorylation regulates hnRNPA2 granule protein partitioning and reduces neurodegeneration.
EMBO J
; 40(3): e105001, 2021 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33349959
7.
Insights into Molecular Diversity within the FUS/EWS/TAF15 Protein Family: Unraveling Phase Separation of the N-Terminal Low-Complexity Domain from RNA-Binding Protein EWS.
J Am Chem Soc
; 146(12): 8071-8085, 2024 Mar 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-38492239
8.
Molecular interactions underlying the phase separation of HP1α: role of phosphorylation, ligand and nucleic acid binding.
Nucleic Acids Res
; 50(22): 12702-12722, 2022 12 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36537242
9.
Amphiphilic proteins coassemble into multiphasic condensates and act as biomolecular surfactants.
Proc Natl Acad Sci U S A
; 118(51)2021 12 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-34916288
10.
Multiscale simulations reveal TDP-43 molecular-level interactions driving condensation.
Biophys J
; 122(22): 4370-4381, 2023 11 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-37853696
11.
The living interface between synthetic biology and biomaterial design.
Nat Mater
; 21(4): 390-397, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35361951
12.
TDP-43 α-helical structure tunes liquid-liquid phase separation and function.
Proc Natl Acad Sci U S A
; 117(11): 5883-5894, 2020 03 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-32132204
13.
Identifying sequence perturbations to an intrinsically disordered protein that determine its phase-separation behavior.
Proc Natl Acad Sci U S A
; 117(21): 11421-11431, 2020 05 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-32393642
14.
Principles Governing the Phase Separation of Multidomain Proteins.
Biochemistry
; 61(22): 2443-2455, 2022 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35802394
15.
Developing Bonded Potentials for a Coarse-Grained Model of Intrinsically Disordered Proteins.
J Chem Inf Model
; 62(18): 4474-4485, 2022 09 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-36066390
16.
Sequence dependent phase separation of protein-polynucleotide mixtures elucidated using molecular simulations.
Nucleic Acids Res
; 48(22): 12593-12603, 2020 12 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-33264400
17.
A predictive coarse-grained model for position-specific effects of post-translational modifications.
Biophys J
; 120(7): 1187-1197, 2021 04 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33582133
18.
Phosphorylation of the FUS low-complexity domain disrupts phase separation, aggregation, and toxicity.
EMBO J
; 36(20): 2951-2967, 2017 10 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-28790177
19.
Biomolecular Phase Separation: From Molecular Driving Forces to Macroscopic Properties.
Annu Rev Phys Chem
; 71: 53-75, 2020 04 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-32312191
20.
Deep learning for characterizing the self-assembly of three-dimensional colloidal systems.
Soft Matter
; 17(4): 989-999, 2021 Jan 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-33284930