A Multigraph-Defined Distribution Function in a Simulation Model of a Communication Network.

We presented a method based on multigraphs to mathematically define a distribution function in time for the generation of data exchange in a special-purpose communication network. This is needed for the modeling and design of communication networks (CNs) consisting of integrated telecommunications and computer networks (ITCN). Simulation models require a precise definition of network traffic communication. An additional problem for describing the network traffic in simulation models is the mathematical model of data distribution, according to which the generation and exchange of certain types and quantities of data are realized. The application of multigraphs enabled the time and quantity of the data distribution to be displayed as operational procedures for a special-purpose communication unit. A multigraph was formed for each data-exchange time and allowed its associated adjacency matrix to be defined. Using the matrix estimation method allowed the mathematical definition of the distribution function values. The application of the described method for the use of multigraphs enabled a more accurate mathematical description of real traffic in communication networks.

A Symbolic Encapsulation Point as Tool for 5G Wideband Channel Cross-Layer Modeling.

Considering that networks based on New Radio (NR) technology are oriented to provide services of desired quality (QoS), it becomes questionable how to model and predict targeted QoS values, especially if the physical channel is dynamically changing. In order to overcome mobility issues, we aim to support the evaluation of second-order statistics of signal, namely level-crossing rate (LCR) and average fade duration (AFD) that is missing in general channel 5G models. Presenting results from our symbolic encapsulation point 5G (SEP5G) additional tool, we fill this gap and motivate further extensions on current general channel 5G. As a matter of contribution, we clearly propose: (i) anadditional tool for encapsulating different mobile 5G modeling approaches; (ii) extended, wideband, LCR, and AFD evaluation for optimal radio resource allocation modeling; and (iii) lower computational complexity and simulation time regarding analytical expression simulations in related scenario-specific 5G channel models. Using our deterministic channel model for selected scenarios and comparing it with stochastic models, we show steps towards higherlevel finite state Markov chain (FSMC) modeling, where mentioned QoS parameters become more feasible, placing symbolic encapsulation at the center of cross-layer design. Furthermore, we generate values within a specified 5G passband, indicating how it can be used for provisioningoptimal radio resource allocation.

An Operation Reduction Using Fast Computation of an Iteration-Based Simulation Method with Microsimulation-Semi-Symbolic Analysis.

This paper presents a method for shortening the computation time and reducing the number of math operations required in complex calculations for the analysis, simulation, and design of processes and systems. The method is suitable for education and engineering applications. The efficacy of the method is illustrated with a case study of a complex wireless communication system. The computer algebra system (CAS) was applied to formulate hypotheses and define the joint probability density function of a certain modulation technique. This innovative method was used to prepare microsimulation-semi-symbolic analyses to fully specify the wireless system. The development of an iteration-based simulation method that provides closed form solutions is presented. Previously, expressions were solved using time-consuming numerical methods. Students can apply this method for performance analysis and to understand data transfer processes. Engineers and researchers may use the method to gain insight into the impact of the parameters necessary to properly transmit and detect information, unlike traditional numerical methods. This research contributes to this field by improving the ability to obtain closed form solutions of the probability density function, outage probability, and considerably improves time efficiency with shortened computation time and reducing the number of calculation operations.

Contrastive Bayesian Analysis for Deep Metric Learning.

Recent methods for deep metric learning have been focusing on designing different contrastive loss functions between positive and negative pairs of samples so that the learned feature embedding is able to pull positive samples of the same class closer and push negative samples from different classes away from each other. In this work, we recognize that there is a significant semantic gap between features at the intermediate feature layer and class labels at the final output layer. To bridge this gap, we develop a contrastive Bayesian analysis to characterize and model the posterior probabilities of image labels conditioned by their features similarity in a contrastive learning setting. This contrastive Bayesian analysis leads to a new loss function for deep metric learning. To improve the generalization capability of the proposed method onto new classes, we further extend the contrastive Bayesian loss with a metric variance constraint. Our experimental results and ablation studies demonstrate that the proposed contrastive Bayesian metric learning method significantly improves the performance of deep metric learning in both supervised and pseudo-supervised scenarios, outperforming existing methods by a large margin.

Using Semantic Web Technologies to Enable Cancer Genomics Discovery at Petabyte Scale.

Increased efforts in cancer genomics research and bioinformatics are producing tremendous amounts of data. These data are diverse in origin, format, and content. As the amount of available sequencing data increase, technologies that make them discoverable and usable are critically needed. In response, we have developed a Semantic Web-based Data Browser, a tool allowing users to visually build and execute ontology-driven queries. This approach simplifies access to available data and improves the process of using them in analyses on the Seven Bridges Cancer Genomics Cloud (CGC; www.cancergenomicscloud.org). The Data Browser makes large data sets easily explorable and simplifies the retrieval of specific data of interest. Although initially implemented on top of The Cancer Genome Atlas (TCGA) data set, the Data Browser's architecture allows for seamless integration of other data sets. By deploying it on the CGC, we have enabled remote researchers to access data and perform collaborative investigations.

The Cancer Genomics Cloud: Collaborative, Reproducible, and Democratized-A New Paradigm in Large-Scale Computational Research.

The Seven Bridges Cancer Genomics Cloud (CGC; www.cancergenomicscloud.org) enables researchers to rapidly access and collaborate on massive public cancer genomic datasets, including The Cancer Genome Atlas. It provides secure on-demand access to data, analysis tools, and computing resources. Researchers from diverse backgrounds can easily visualize, query, and explore cancer genomic datasets visually or programmatically. Data of interest can be immediately analyzed in the cloud using more than 200 preinstalled, curated bioinformatics tools and workflows. Researchers can also extend the functionality of the platform by adding their own data and tools via an intuitive software development kit. By colocalizing these resources in the cloud, the CGC enables scalable, reproducible analyses. Researchers worldwide can use the CGC to investigate key questions in cancer genomics. Cancer Res; 77(21); e3-6. ©2017 AACR.