Detalhe da pesquisa
1.
Recommendations on the Use of Multiple Labels in Human Mass Balance Studies.
Drug Metab Dispos
; 52(3): 153-158, 2024 Feb 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-38216306
2.
Preclinical in vitro and in vivo pharmacokinetic properties of danicamtiv, a new targeted myosin activator for the treatment of dilated cardiomyopathy.
Xenobiotica
; 51(2): 222-238, 2021 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-33078965
3.
Morphological behaviour and metabolic capacity of cryopreserved human primary hepatocytes cultivated in a perfused multiwell device.
Xenobiotica
; 45(1): 29-44, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25068923
4.
Metabolite Bioanalysis in Drug Development: Recommendations from the IQ Consortium Metabolite Bioanalysis Working Group.
Clin Pharmacol Ther
; 115(5): 939-953, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38073140
5.
Absorption, Metabolism, and Excretion of [14C]-Tolebrutinib After Oral Administration in Humans, Contribution of the Metabolites to Pharmacological Activity.
Clin Drug Investig
; 43(8): 653-665, 2023 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-37642857
6.
Considerations for Human ADME Strategy and Design Paradigm Shift(s) - An Industry White Paper.
Clin Pharmacol Ther
; 113(4): 775-781, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35733280
7.
Identification of metabolic pathways and enzyme systems involved in the in vitro human hepatic metabolism of dronedarone, a potent new oral antiarrhythmic drug.
Pharmacol Res Perspect
; 2(3): e00044, 2014 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-25505590