Detalhe da pesquisa
1.
ACE2 and TMPRSS2 SARS-CoV-2 infectivity genes: deep mutational scanning and characterization of missense variants.
Hum Mol Genet
; 31(24): 4183-4192, 2022 12 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-35861636
2.
IL17RB genetic variants are associated with acamprosate treatment response in patients with alcohol use disorder: A proteomics-informed genomics study.
Brain Behav Immun
; 120: 304-314, 2024 Jun 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-38852760
3.
Single cell transcriptomics reveals distinct transcriptional responses to oxycodone and buprenorphine by iPSC-derived brain organoids from patients with opioid use disorder.
Mol Psychiatry
; 2022 Oct 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-36302966
4.
TSPAN5 influences serotonin and kynurenine: pharmacogenomic mechanisms related to alcohol use disorder and acamprosate treatment response.
Mol Psychiatry
; 26(7): 3122-3133, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32753686
5.
SLCO1B1: Application and Limitations of Deep Mutational Scanning for Genomic Missense Variant Function.
Drug Metab Dispos
; 49(5): 395-404, 2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33658230
6.
Pharmacogenomic Next-Generation DNA Sequencing: Lessons from the Identification and Functional Characterization of Variants of Unknown Significance in CYP2C9 and CYP2C19.
Drug Metab Dispos
; 47(4): 425-435, 2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30745309
7.
Molecular mechanisms involved in alcohol craving, IRF3, and endoplasmic reticulum stress: a multi-omics study.
Transl Psychiatry
; 14(1): 165, 2024 Mar 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-38531832
8.
FKBP5 genetic variation: association with selective serotonin reuptake inhibitor treatment outcomes in major depressive disorder.
Pharmacogenet Genomics
; 23(3): 156-66, 2013 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-23324805
9.
Epigenetic regulation of GABA catabolism in iPSC-derived neurons: The molecular links between FGF21 and histone methylation.
Mol Metab
; 77: 101798, 2023 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-37689244
10.
Gemcitabine metabolic pathway genetic polymorphisms and response in patients with non-small cell lung cancer.
Pharmacogenet Genomics
; 22(2): 105-16, 2012 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-22173087
11.
Human liver methionine cycle: MAT1A and GNMT gene resequencing, functional genomics, and hepatic genotype-phenotype correlation.
Drug Metab Dispos
; 40(10): 1984-92, 2012 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-22807109
12.
Genome-wide association study for circulating FGF21 in patients with alcohol use disorder: Molecular links between the SNHG16 locus and catecholamine metabolism.
Mol Metab
; 63: 101534, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35752286
13.
Genetic variants associated with acamprosate treatment response in alcohol use disorder patients: A multiple omics study.
Br J Pharmacol
; 179(13): 3330-3345, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35016259
14.
Plasma TNFSF10 levels associated with acamprosate treatment response in patients with alcohol use disorder.
Front Pharmacol
; 13: 986238, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36120372
15.
A novel application of pattern recognition for accurate SNP and indel discovery from high-throughput data: targeted resequencing of the glucocorticoid receptor co-chaperone FKBP5 in a Caucasian population.
Mol Genet Metab
; 104(4): 457-69, 2011 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-21917492
16.
Methionine adenosyltransferase 2A/2B and methylation: gene sequence variation and functional genomics.
Drug Metab Dispos
; 39(11): 2135-47, 2011 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-21813468
17.
All-trans- and 9-cis-retinoic acids activate the human cyclooxynase-2 gene: a role for DR1 as RARE or RXRE.
Mol Biol Rep
; 38(2): 833-40, 2011 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-20376700
18.
Natriuretic peptide pharmacogenetics: membrane metallo-endopeptidase (MME): common gene sequence variation, functional characterization and degradation.
J Mol Cell Cardiol
; 49(5): 864-74, 2010 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-20692264
19.
Ecto-5'-nucleotidase and thiopurine cellular circulation: association with cytotoxicity.
Drug Metab Dispos
; 38(12): 2329-38, 2010 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-20855458
20.
CYP2C9 and CYP2C19: Deep Mutational Scanning and Functional Characterization of Genomic Missense Variants.
Clin Transl Sci
; 13(4): 727-742, 2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32004414