Detalhe da pesquisa
1.
HTS-compatible FRET-based conformational sensors clarify membrane receptor activation.
Nat Chem Biol
; 13(4): 372-380, 2017 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28135236
2.
Orexin-corticotropin-releasing factor receptor heteromers in the ventral tegmental area as targets for cocaine.
J Neurosci
; 35(17): 6639-53, 2015 Apr 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-25926444
3.
Cocaine disrupts histamine H3 receptor modulation of dopamine D1 receptor signaling: σ1-D1-H3 receptor complexes as key targets for reducing cocaine's effects.
J Neurosci
; 34(10): 3545-58, 2014 Mar 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-24599455
4.
Circadian-related heteromerization of adrenergic and dopamine D4 receptors modulates melatonin synthesis and release in the pineal gland.
PLoS Biol
; 10(6): e1001347, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22723743
5.
Cannabinoid receptors CB1 and CB2 form functional heteromers in brain.
J Biol Chem
; 287(25): 20851-65, 2012 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22532560
6.
Spontaneous changes in brain striatal dopamine synthesis and storage dynamics ex vivo reveal end-product feedback-inhibition of tyrosine hydroxylase.
Neuropharmacology
; 212: 109058, 2022 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35429504
7.
Modulation of dopamine D1 receptors via histamine H3 receptors is a novel therapeutic target for Huntington's disease.
Elife
; 92020 06 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32513388
8.
D1-mGlu5 heteromers mediate noncanonical dopamine signaling in Parkinson's disease.
J Clin Invest
; 130(3): 1168-1184, 2020 03 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-32039920
9.
Discovery of a small molecule modulator of the Kv1.1/Kvß1 channel complex that reduces neuronal excitability and in vitro epileptiform activity.
CNS Neurosci Ther
; 25(4): 442-451, 2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30242974
10.
Class C G protein-coupled receptors: reviving old couples with new partners.
Biophys Rep
; 3(4): 57-63, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-29238742
11.
Heteroreceptor Complexes Formed by Dopamine D1, Histamine H3, and N-Methyl-D-Aspartate Glutamate Receptors as Targets to Prevent Neuronal Death in Alzheimer's Disease.
Mol Neurobiol
; 54(6): 4537-4550, 2017 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27370794
12.
Allosteric control of an asymmetric transduction in a G protein-coupled receptor heterodimer.
Elife
; 62017 08 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-28829739
13.
Allosteric nanobodies uncover a role of hippocampal mGlu2 receptor homodimers in contextual fear consolidation.
Nat Commun
; 8(1): 1967, 2017 12 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29213077
14.
Pharmacological evidence for a metabotropic glutamate receptor heterodimer in neuronal cells.
Elife
; 62017 06 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-28661401
15.
Constitutive activity of H3 autoreceptors modulates histamine synthesis in rat brain through the cAMP/PKA pathway.
Neuropharmacology
; 51(3): 517-23, 2006 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-16769092
16.
H3 autoreceptors modulate histamine synthesis through calcium/calmodulin- and cAMP-dependent protein kinase pathways.
Mol Pharmacol
; 67(1): 195-203, 2005 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-15465923