Pesquisa | Portal de Pesquisa da BVS Enfermagem

1.

The rare C9 P167S risk variant for age-related macular degeneration increases polymerization of the terminal component of the complement cascade.

McMahon, O; Hallam, T M; Patel, S; Harris, C L; Menny, A; Zelek, W M; Widjajahakim, R; Java, A; Cox, T E; Tzoumas, N; Steel, D H W; Shuttleworth, V G; Smith-Jackson, K; Brocklebank, V; Griffiths, H; Cree, A J; Atkinson, J P; Lotery, A J; Bubeck, D; Morgan, B P; Marchbank, K J; Seddon, J M; Kavanagh, D.

Hum Mol Genet ; 30(13): 1188-1199, 2021 06 17.

Artigo em Inglês | MEDLINE | ID: mdl-33783477

2.

Ethnic differences in complement system biomarkers and their association with metabolic health in men of Black African and White European ethnicity.

Goff, L M; Davies, K; Zelek, W M; Kodosaki, E; Hakim, O; Lockhart, S; O'Rahilly, S; Morgan, B P.

Clin Exp Immunol ; 212(1): 52-60, 2023 04 07.

Artigo em Inglês | MEDLINE | ID: mdl-36722378

3.

Complement activation and expression during chronic relapsing experimental autoimmune encephalomyelitis in the Biozzi ABH mouse.

Ramaglia, V; Jackson, S J; Hughes, T R; Neal, J W; Baker, D; Morgan, B P.

Clin Exp Immunol ; 180(3): 432-41, 2015 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-25619542

4.

Systemic complement profiling in multiple sclerosis as a biomarker of disease state.

Ingram, G; Hakobyan, S; Hirst, C L; Harris, C L; Loveless, S; Mitchell, J P; Pickersgill, T P; Robertson, N P; Morgan, B P.

Mult Scler ; 18(10): 1401-11, 2012 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-22354735

5.

Mutational analysis of the active site and antibody epitopes of the complement-inhibitory glycoprotein, CD59.

Bodian, D L; Davis, S J; Morgan, B P; Rushmere, N K.

J Exp Med ; 185(3): 507-16, 1997 Feb 03.

Artigo em Inglês | MEDLINE | ID: mdl-9053451

6.

Physiologic relevance of the membrane attack complex inhibitory protein CD59 in human seminal plasma: CD59 is present on extracellular organelles (prostasomes), binds cell membranes, and inhibits complement-mediated lysis.

Rooney, I A; Atkinson, J P; Krul, E S; Schonfeld, G; Polakoski, K; Saffitz, J E; Morgan, B P.

J Exp Med ; 177(5): 1409-20, 1993 May 01.

Artigo em Inglês | MEDLINE | ID: mdl-7683035

7.

In vivo effects of monoclonal antibodies that functionally inhibit complement regulatory proteins in rats.

Matsuo, S; Ichida, S; Takizawa, H; Okada, N; Baranyi, L; Iguchi, A; Morgan, B P; Okada, H.

J Exp Med ; 180(5): 1619-27, 1994 Nov 01.

Artigo em Inglês | MEDLINE | ID: mdl-7525834

8.

Human protectin (CD59), an 18-20-kD homologous complement restriction factor, does not restrict perforin-mediated lysis.

Meri, S; Morgan, B P; Wing, M; Jones, J; Davies, A; Podack, E; Lachmann, P J.

J Exp Med ; 172(1): 367-70, 1990 Jul 01.

Artigo em Inglês | MEDLINE | ID: mdl-1694224

9.

Innate recognition of bacteria in human milk is mediated by a milk-derived highly expressed pattern recognition receptor, soluble CD14.

Labéta, M O; Vidal, K; Nores, J E; Arias, M; Vita, N; Morgan, B P; Guillemot, J C; Loyaux, D; Ferrara, P; Schmid, D; Affolter, M; Borysiewicz, L K; Donnet-Hughes, A; Schiffrin, E J.

J Exp Med ; 191(10): 1807-12, 2000 May 15.

Artigo em Inglês | MEDLINE | ID: mdl-10811873

10.

Systemic and local anti-C5 therapy reduces the disease severity in experimental autoimmune uveoretinitis.

Copland, D A; Hussain, K; Baalasubramanian, S; Hughes, T R; Morgan, B P; Xu, H; Dick, A D; Nicholson, L B.

Clin Exp Immunol ; 159(3): 303-14, 2010 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-20002447

11.

Upregulating CD59: a new strategy for protection of neurons from complement-mediated degeneration.

Kolev, M V; Tediose, T; Sivasankar, B; Harris, C L; Thome, J; Morgan, B P; Donev, R M.

Pharmacogenomics J ; 10(1): 12-9, 2010 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-19884909

12.

A novel mutation in a patient with a deficiency of the eighth component of complement associated with recurrent meningococcal meningitis.

Arnold, D F; Roberts, A G; Thomas, A; Ferry, B; Morgan, B P; Chapel, H.

J Clin Immunol ; 29(5): 691-5, 2009 Sep.

Artigo em Inglês | MEDLINE | ID: mdl-19434484

13.

Complement in multiple sclerosis: its role in disease and potential as a biomarker.

Ingram, G; Hakobyan, S; Robertson, N P; Morgan, B P.

Clin Exp Immunol ; 155(2): 128-39, 2009 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-19040603

14.

Exogenous glycosyl phosphatidylinositol-anchored CD59 associates with kinases in membrane clusters on U937 cells and becomes Ca(2+)-signaling competent.

van den Berg, C W; Cinek, T; Hallett, M B; Horejsi, V; Morgan, B P.

J Cell Biol ; 131(3): 669-77, 1995 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-7593188

15.

Complement, roles in renal disease and modulation for therapy.

Hepburn, N J; Ruseva, M M; Harris, C L; Morgan, B P.

Clin Nephrol ; 70(5): 357-76, 2008 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-19000536

16.

Immunology of reproduction: protecting the placenta.

Morgan, B P; Holmes, C H.

Curr Biol ; 10(10): R381-3, 2000 May 18.

Artigo em Inglês | MEDLINE | ID: mdl-10837212

17.

Tubulointerstitial injury induced in rats by a monoclonal antibody that inhibits function of a membrane inhibitor of complement.

Nomura, A; Nishikawa, K; Yuzawa, Y; Okada, H; Okada, N; Morgan, B P; Piddlesden, S J; Nadai, M; Hasegawa, T; Matsuo, S.

J Clin Invest ; 96(5): 2348-56, 1995 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-7593622

18.

Thrombomodulin enhances complement regulation through strong affinity interactions with factor H and C3b-Factor H complex.

Heurich, M; Preston, R J S; O'Donnell, V B; Morgan, B P; Collins, P W.

Thromb Res ; 145: 84-92, 2016 Sep.

Artigo em Inglês | MEDLINE | ID: mdl-27513882

19.

The inhibition of phospholipase A2 by manoalide and manoalide analogues.

Deems, R A; Lombardo, D; Morgan, B P; Mihelich, E D; Dennis, E A.

Biochim Biophys Acta ; 917(2): 258-68, 1987 Feb 14.

Artigo em Inglês | MEDLINE | ID: mdl-3801502

20.

Target-sensitive immunoerythrocytes: interaction of biotinylated red blood cells with immobilized avidin induces their lysis by complement.

Muzykantov, V R; Zaltsman, A B; Smirnov, M D; Samokhin, G P; Morgan, B P.

Biochim Biophys Acta ; 1279(2): 137-43, 1996 Mar 13.

Artigo em Inglês | MEDLINE | ID: mdl-8603079

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