Detalhe da pesquisa
1.
A genetically encoded fluorescent sensor for manganese(II), engineered from lanmodulin.
Proc Natl Acad Sci U S A
; 119(51): e2212723119, 2022 12 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-36508659
2.
Up-regulation of the manganese transporter SLC30A10 by hypoxia-inducible factors defines a homeostatic response to manganese toxicity.
Proc Natl Acad Sci U S A
; 118(35)2021 08 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-34446561
3.
Manganese efflux transporter SLC30A10 missense polymorphism T95I associated with liver injury retains manganese efflux activity.
Am J Physiol Gastrointest Liver Physiol
; 324(1): G78-G88, 2023 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36414535
4.
Hepatic and intestinal manganese excretion are both required to regulate brain manganese during elevated manganese exposure.
Am J Physiol Gastrointest Liver Physiol
; 325(3): G251-G264, 2023 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37461848
5.
Manganese and thyroid function in the national health and nutrition examination survey, 2011-2012.
Environ Res
; 222: 115371, 2023 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36709872
6.
A three-pocket model for substrate coordination and selectivity by the nucleotide sugar transporters SLC35A1 and SLC35A2.
J Biol Chem
; 297(3): 101069, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34384782
7.
Role of excretion in manganese homeostasis and neurotoxicity: a historical perspective.
Am J Physiol Gastrointest Liver Physiol
; 322(1): G79-G92, 2022 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34786983
8.
Brain manganese and the balance between essential roles and neurotoxicity.
J Biol Chem
; 295(19): 6312-6329, 2020 05 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32188696
9.
SLC30A10 transporter in the digestive system regulates brain manganese under basal conditions while brain SLC30A10 protects against neurotoxicity.
J Biol Chem
; 294(6): 1860-1876, 2019 02 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-30559290
10.
Maintaining Translational Relevance in Animal Models of Manganese Neurotoxicity.
J Nutr
; 150(6): 1360-1369, 2020 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32211802
11.
Functional analyses of the UDP-galactose transporter SLC35A2 using the binding of bacterial Shiga toxins as a novel activity assay.
Glycobiology
; 29(6): 490-503, 2019 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30834435
12.
Deficiency in the manganese efflux transporter SLC30A10 induces severe hypothyroidism in mice.
J Biol Chem
; 292(23): 9760-9773, 2017 06 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-28461334
13.
Hypothyroidism induced by loss of the manganese efflux transporter SLC30A10 may be explained by reduced thyroxine production.
J Biol Chem
; 292(40): 16605-16615, 2017 10 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28860195
14.
A Conserved Structural Motif Mediates Retrograde Trafficking of Shiga Toxin Types 1 and 2.
Traffic
; 16(12): 1270-87, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26420131
15.
Structural Elements in the Transmembrane and Cytoplasmic Domains of the Metal Transporter SLC30A10 Are Required for Its Manganese Efflux Activity.
J Biol Chem
; 291(31): 15940-57, 2016 07 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-27307044
16.
SLC30A10 is a cell surface-localized manganese efflux transporter, and parkinsonism-causing mutations block its intracellular trafficking and efflux activity.
J Neurosci
; 34(42): 14079-95, 2014 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25319704
17.
Manganese homeostasis in the nervous system.
J Neurochem
; 134(4): 601-10, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-25982296
18.
Identification of a gain-of-function mutation in a Golgi P-type ATPase that enhances Mn2+ efflux and protects against toxicity.
Proc Natl Acad Sci U S A
; 108(2): 858-63, 2011 Jan 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-21187401
19.
Loss of SLC30A10 manganese transporter alters expression of neurotransmission genes and activates hypoxia-inducible factor signaling in mice.
Metallomics
; 16(2)2024 02 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-38285613
20.
Unexpected inhibition of the lipid kinase PIKfyve reveals an epistatic role for p38 MAPKs in endolysosomal fission and volume control.
Cell Death Dis
; 15(1): 80, 2024 01 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-38253602