Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 20 de 110
Filtrar
Mais filtros

Bases de dados
Tipo de documento
Intervalo de ano de publicação
1.
J Clean Prod ; 279: 123586, 2021 Jan 10.
Artigo em Inglês | MEDLINE | ID: mdl-32836913

RESUMO

Sustainability certification schemes such as FAIRTRADE, FLO, WFTO and FT-USA have gained increasing markets. The significant growth of the fair trade (FT) movement in the last decades draws attention to ethical consumption. FT's aim at improving the livelihoods of producers in developing countries and promotion of social change is considered a model that shows the benefits of trade to development. Although conveying a large number of publications, important questions about the movement remain under-explored. The literature is prolific on coffee, cacao, flowers, wine, and gold. In contrast, the engagement with staple foods - a prominent globally traded food category - seems minor. The primary objective of this review was to map the existing literature about FT and staple foods; then, to investigate the role of staple foods in the FT movement. The search strategy was designed to retrieve publications on the intersection of FT and staple foods. To date, there is no review about FT and staple foods nexus. Our systematic review addressed this gap considering FT as an alternative capable of addressing unsustainable food consumption and production impacts. Our research protocol included keywords searching across four databases, screening, and comparative analysis. From 283 documents retrieved, 49 were deemed relevant to reflect the role of staple foods in the FT movement. This systematic review discusses challenges and opportunities for the FT model to further engage with staples and recommends improvement of its environmental credentials. The present study can contribute by informing decision makers, policy makers, businesses, NGOs, producers, and consumers.

2.
Cereb Cortex ; 29(6): 2470-2481, 2019 06 01.
Artigo em Inglês | MEDLINE | ID: mdl-29878066

RESUMO

Recent studies of semantic memory have focused on dissociating the neural bases of two foundational components of human thought: taxonomic categories, which group similar objects like dogs and seals based on features, and thematic categories, which group dissimilar objects like dogs and leashes based on events. While there is emerging consensus that taxonomic concepts are represented in the anterior temporal lobe, there is disagreement over whether thematic concepts are represented in the angular gyrus (AG). We previously found AG sensitivity to both kinds of concepts; however, some accounts suggest that such activity reflects inhibition of irrelevant information rather than thematic activation. To test these possibilities, an fMRI experiment investigated both types of conceptual relations in the AG during two semantic judgment tasks. Each task trained participants to give negative responses (inhibition) or positive responses (activation) to word pairs based on taxonomic and thematic criteria of relatedness. Results showed AG engagement during both negative judgments and thematic judgments, but not during positive judgments about taxonomic pairs. Together, the results suggest that activity in the AG reflects functions that include both thematic (but not taxonomic) processing and inhibiting irrelevant semantic information.


Assuntos
Formação de Conceito/fisiologia , Lobo Parietal/fisiologia , Semântica , Adulto , Mapeamento Encefálico/métodos , Feminino , Humanos , Processamento de Imagem Assistida por Computador/métodos , Imageamento por Ressonância Magnética/métodos , Masculino , Memória/fisiologia
3.
Can J Urol ; 27(3): 10228-10232, 2020 06.
Artigo em Inglês | MEDLINE | ID: mdl-32544045

RESUMO

INTRODUCTION: To evaluate flexible pediatric cystoscopy (FPC) as an adjunctive procedure to retrograde urethrography (RUG) and voiding cystourethrography (VCUG) in the preoperative setting for male urethral strictures. Since imaging interpretation of stricture length and caliber can be difficult at times, we sought to evaluate diagnostic utility of FPC to predict reconstructive surgery. MATERIALS AND METHODS: Reconstructive urology databases at Washington University and Columbia University were queried from 2010-2017. A total of 185 anterior urethroplasty patients met inclusion criteria. All surgeries were performed by a single surgeon. There were 102 patients that underwent preoperative FPC (7.5 Fr in diameter). Surgical urethroplasty techniques employed were: ventral or dorsal onlay buccal mucosa graft, fasciocutaneous penile skin flap, excision and primary anastomosis or augmented anastomotic. We analyzed the RUG, VCUG, FPC, and intraoperative details of the urethral strictures by univariate and multivariate statistics. RESULTS: Mean patient age was 47.2 (+/-16.5) years. Of the patients who underwent FPC, 42.2% were narrower than the FPC, and 57.8% were wider. Intraoperative stricture length better correlated with FPC findings compared to RUG/ VCUG (r = 0.834 versus r = 0.766) (p < 0.001). Moreover, inability to pass the FPC through the stricture correlated with the need to perform urethral stricture excision or complete reconstruction of the urethral plate (p = 0.005), rather than onlay urethroplasty. CONCLUSION: Preoperative FPC is a useful adjunctive tool in the evaluation of urethral strictures. FPC facilitates stricture assessment by accurately correlating with intraoperative stricture length and predicting the need to excise or graft during reconstruction.


Assuntos
Tomada de Decisão Clínica , Cistoscopia , Uretra/cirurgia , Estreitamento Uretral/patologia , Estreitamento Uretral/cirurgia , Adulto , Humanos , Masculino , Pessoa de Meia-Idade , Período Pré-Operatório , Reprodutibilidade dos Testes , Estudos Retrospectivos , Procedimentos Cirúrgicos Urológicos Masculinos/métodos
4.
J Urol ; 201(5): 956-961, 2019 05.
Artigo em Inglês | MEDLINE | ID: mdl-30676476

RESUMO

PURPOSE: Perineal urethrostomy is a viable option for many complex urethral strictures. However, to our knowledge no comparison with anterior urethroplasty regarding patient reported outcome measures has been published. We compared these groups using a large multi-institution database. MATERIALS AND METHODS: We performed a retrospective study of anterior urethroplasty in the TURNS (Trauma and Urologic Reconstructive Network of Surgeons) database. The anterior urethroplasty cohort was defined by long strictures greater than 6 cm. We compared demographic, clinical, urinary and sexual characteristics using validated patient reported outcome measures between patients treated with long stricture anterior urethroplasty and those who underwent perineal urethrostomy. RESULTS: Of the 131 patients 92 treated with long stricture anterior urethroplasty and 39 treated with perineal urethrostomy met study inclusion criteria. The cumulative incidence of failure at 2 years was 30.2% (95% CI 18.3-47.3) for long stricture anterior urethroplasty and 14.5% (95% CI 4.8-39.1) for perineal urethrostomy (p = 0.09). Compared to baseline metrics, patients who underwent long stricture anterior urethroplasty and perineal urethrostomy had similar improvements in urinary function and stable sexual function after surgery. CONCLUSIONS: Patients reported improvement in urinary function after perineal urethrostomy with no deleterious effect on sexual function. These patient reported outcome measures were comparable to those of long stricture anterior urethroplasty. Perineal urethrostomy failure rates were similar to those of long stricture anterior urethroplasty.


Assuntos
Satisfação do Paciente/estatística & dados numéricos , Comportamento Sexual/fisiologia , Estreitamento Uretral/cirurgia , Micção/fisiologia , Procedimentos Cirúrgicos Urológicos Masculinos/métodos , Adulto , Idoso , Estudos de Coortes , Intervalos de Confiança , Bases de Dados Factuais , Seguimentos , Humanos , Masculino , Pessoa de Meia-Idade , Períneo/cirurgia , Recuperação de Função Fisiológica , Estudos Retrospectivos , Medição de Risco , Índice de Gravidade de Doença , Resultado do Tratamento , Estreitamento Uretral/diagnóstico
5.
World J Urol ; 37(7): 1455-1459, 2019 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-30276541

RESUMO

PURPOSE: Guidelines call for routine reimaging of Grade 4-5 renal injuries at 48-72 h. The aim of the current study is to evaluate the clinical utility of computed tomography (CT) reimaging in high-grade renal injuries. MATERIALS AND METHODS: We assembled data on 216 trauma patients with high-grade renal trauma at three level 1 trauma centers over a 19-year span between 1999 and 2017 in retrospectively collected trauma database. Demographic, radiographic, and clinical characteristics of patients were retrospectively reviewed. RESULTS: In total, 151 cases were Grade 4 renal injuries, and 65 were Grade 5 renal injuries. 53.6% (81) Grade 4 and 15.4% (10) Grade 5 renal injuries were initially managed conservatively. Of the 6 asymptomatic cases where repeat imaging resulted in intervention, 100% had collecting system injuries at initial imaging. Collecting system injuries were only present in 42.9% of cases where routine repeat imaging did not trigger surgical intervention. Collecting system injury at the time of initial imaging was a statistically significant predictor of routine repeat imaging triggering surgical intervention (p = 0.022). Trauma grade and the presence of vascular injury were not significant predictors of intervention after repeat imaging in asymptomatic patients. CONCLUSION: In asymptomatic patients with high-grade renal trauma, the number needed to image is approximately one in eight (12.5%) to identify need for surgical intervention. There is potentially room to improve criteria for routine renal imaging in high-grade renal trauma based on the more predictive imaging finding of collecting system injury.


Assuntos
Traumatismos Abdominais/diagnóstico por imagem , Hemorragia/diagnóstico por imagem , Rim/diagnóstico por imagem , Rim/lesões , Traumatismos Abdominais/terapia , Adulto , Doenças Assintomáticas , Tratamento Conservador , Embolização Terapêutica , Feminino , Hemorragia/terapia , Humanos , Rim/cirurgia , Túbulos Renais/diagnóstico por imagem , Túbulos Renais/lesões , Masculino , Estudos Retrospectivos , Tomografia Computadorizada por Raios X , Centros de Traumatologia , Índices de Gravidade do Trauma , Urinoma/diagnóstico por imagem , Urinoma/terapia , Lesões do Sistema Vascular/diagnóstico por imagem , Lesões do Sistema Vascular/terapia , Ferimentos Penetrantes/diagnóstico por imagem
6.
Spinal Cord ; 57(3): 221-228, 2019 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-30262878

RESUMO

STUDY DESIGN: A prospective, parallel randomized controlled trial (RCT). OBJECTIVES: To test the preliminary effects of an online resource targeted to job-seekers with spinal cord injury or disorder (SCI/D), and to determine the feasibility of proceeding to a full-scale RCT. SETTING: A community cohort in Australia. METHODS: Forty-eight adults (M = 42 years, SD = 10.95, 27 males) were randomized to receive 4-weeks access to the Work and SCI resource (n = 25) or to a wait-list control group (n = 23). The Work and SCI intervention involved six stand-alone learning modules which provided job-searching and career-planning information through text, videos, and interactive activities. Self-report measures were administered at baseline and after 4 weeks: Job Procurement Self-Efficacy Scale (JSES), Life Orientation Test-Revised (LOT-R), and Patient Health Questionnaire-9 (PHQ-9). RESULTS: Online usage data identified high uptake of the Work and SCI resource, although study attrition was problematic. Intention-to-treat analyses failed to reach statistical significance, whereas complete data revealed a significant interaction effect for optimism (LOT-R). CONCLUSION: Further research to develop and enhance Work and SCI is indicated. Remediable strategies to optimize recruitment and statistical power in a future definitive RCT are discussed. SPONSORSHIP: This project was funded by the auDA Foundation (project 16019).


Assuntos
Emprego , Internet , Terapia Ocupacional , Doenças da Medula Espinal/reabilitação , Traumatismos da Medula Espinal/reabilitação , Telerreabilitação , Adulto , Emprego/psicologia , Estudos de Viabilidade , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Otimismo , Aceitação pelo Paciente de Cuidados de Saúde , Projetos Piloto , Autoeficácia , Doenças da Medula Espinal/psicologia , Traumatismos da Medula Espinal/psicologia , Resultado do Tratamento , Adulto Jovem
7.
J Urol ; 199(2): 552-557, 2018 02.
Artigo em Inglês | MEDLINE | ID: mdl-28899768

RESUMO

PURPOSE: Efforts have been made to reduce use of computerized tomography in children with blunt abdominal injury. Computerized tomography may be overused in pediatric patients with renal trauma. MATERIALS AND METHODS: We performed a retrospective chart review of all renal trauma patients younger than 18 years old treated at 2 urban trauma centers from 2002 to 2016. We collected demographic and clinical characteristics, renal trauma grades, urological interventions, and timing and use of computerized tomography and renal ultrasound. RESULTS: During the study period 145 patients presented with blunt renal trauma. During hospitalization 46 patients (32%) underwent repeat computerized tomography. About 20% of repeat computerized tomograms were performed less than 48 hours after the first scan. After controlling for center, isolated injury (yes/no), stent placement, age and surgical interventions (yes/no) patients who underwent delayed imaging on their first scan had decreased odds of undergoing a second computerized tomogram (adjusted OR 0.2, 95% CI 0.05-0.9, p = 0.04). Number needed to treat to prevent 1 repeat scan in high grade renal trauma patients was 3 (95% CI 2-4). Estimated sensitivity and specificity for ultrasound monitoring to detect an abnormality requiring urological intervention are 50% and 94%, respectively. CONCLUSIONS: Repeat computerized tomography in pediatric patients with renal trauma is common. Obtaining delayed imaging on the initial scan in patients with high grade renal trauma may prevent repeat scans. Renal ultrasound provides diagnostic usefulness in monitoring kidney injuries and should be considered before repeating computerized tomography.


Assuntos
Traumatismos Abdominais/diagnóstico por imagem , Rim/diagnóstico por imagem , Exposição à Radiação/prevenção & controle , Tomografia Computadorizada por Raios X/efeitos adversos , Centros de Traumatologia , Ferimentos não Penetrantes/diagnóstico por imagem , Traumatismos Abdominais/terapia , Adolescente , Criança , Feminino , Humanos , Rim/lesões , Rim/cirurgia , Masculino , Estudos Retrospectivos , Tomografia Computadorizada por Raios X/métodos , Ultrassonografia , População Urbana , Ferimentos não Penetrantes/terapia
8.
J Urol ; 199(3): 760-765, 2018 03.
Artigo em Inglês | MEDLINE | ID: mdl-29032297

RESUMO

PURPOSE: Studies of surgical complications of penile inversion vaginoplasty are limited due to small sample sizes. We describe postoperative complications after penile inversion vaginoplasty and evaluated age, body mass index and years on hormone replacement therapy as risk factors for complications. MATERIALS AND METHODS: We retrospectively reviewed the records of male-to-female patients who presented for primary penile inversion vaginoplasty to a high volume surgeon (MLB) from 2011 to 2015. Complications included granulation tissue, vaginal pain, wound separation, labial asymmetry, vaginal stenosis, fistula formation, urinary symptoms including spraying stream or dribbling, infection, vaginal fissure or vaginal bleeding. We classified complications by Clavien-Dindo grade. Multivariable logistic regression was performed to determine the independent effects of age, body mass index and hormone replacement therapy on postoperative surgical complications. RESULTS: A total of 330 patients presented for primary penile inversion vaginoplasty. Median age at surgery was 35 years (range 18 to 76). Median followup in all patients was 3 months (range 3 to 73). Of the patients 95 (28.7%) presented with a postoperative complication. Median time to a complication was 4.4 months (IQR 1-11.5). Rectoneovaginal fistulas developed in 3 patients (0.9%). A total of 30 patients (9.0%) required a second operation. There were no complications greater than Clavien-Dindo grade IIIB. Age, body mass index and hormone replacement therapy were not associated with complications. CONCLUSIONS: Penile inversion vaginoplasty is a relatively safe procedure. Most complications due to this surgery develop within the first 4 months postoperatively. Age, body mass index and hormone replacement therapy are not associated with complications and, thus, they should not dictate the timing of surgery.


Assuntos
Pênis/cirurgia , Complicações Pós-Operatórias/epidemiologia , Cirurgia de Readequação Sexual/métodos , Estruturas Criadas Cirurgicamente , Pessoas Transgênero , Transexualidade/cirurgia , Vagina/cirurgia , Adolescente , Adulto , Idoso , Feminino , Seguimentos , Humanos , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos , Resultado do Tratamento , Estados Unidos/epidemiologia , Adulto Jovem
9.
J Urol ; 199(3): 785-790, 2018 03.
Artigo em Inglês | MEDLINE | ID: mdl-28964781

RESUMO

PURPOSE: Patient centered data are lacking regarding functional and quality of life improvements after artificial urinary sphincter placement. We analyzed the degree of benefit from artificial urinary sphincter placement using ISI (Incontinence Symptom Index), a validated patient reported outcome measure assessing the severity and bother of urinary incontinence, and IIQ-7 (Incontinence Impact Questionnaire-7), a validated patient reported outcome measure assessing the impact and emotional distress of urinary incontinence. MATERIALS AND METHODS: We performed a retrospective review at 4 centers participating in TURNS (Trauma and Urologic Reconstruction Network of Surgeons). Data were available on 51 and 45 patients who underwent artificial urinary sphincter placement, and had preoperative and postoperative ISI and IIQ-7 data, respectively. RESULTS: Mean age was 64.8 years. Median time from surgery to followup questionnaires was 8.5 months. On ISI the median preoperative severity and bother scores were 24 (IQR 20-28.5) and 6 (IQR 4-7), and the median postoperative severity and bother scores were 10 (IQR 4.5-17) and 1 (IQR 0-3), respectively. Improvement on each ISI item was statistically significant. On IIQ-7 the median preoperative impact and distress scores were 9 (IQR 6-13) and 4 (IQR 2-6), and the median postoperative impact and distress scores were 3 (IQR 0-7) and 0 (IQR 0-3), respectively. Improvement on each IIQ-7 item was statistically significant. CONCLUSIONS: Artificial urinary sphincter implantation significantly reduces the severity and bother of stress urinary incontinence symptoms. Longer followup and development are needed of a patient reported outcome measure targeting male stress urinary incontinence.


Assuntos
Medidas de Resultados Relatados pelo Paciente , Qualidade de Vida , Incontinência Urinária por Estresse/cirurgia , Esfíncter Urinário Artificial , Micção/fisiologia , Procedimentos Cirúrgicos Urológicos Masculinos/métodos , Seguimentos , Humanos , Masculino , Pessoa de Meia-Idade , Estudos Prospectivos , Incontinência Urinária por Estresse/fisiopatologia , Incontinência Urinária por Estresse/psicologia
10.
J Urol ; 199(3): 798-804, 2018 03.
Artigo em Inglês | MEDLINE | ID: mdl-29031767

RESUMO

PURPOSE: We explored the relation of cycling to urinary and sexual function in a large multinational sample of men. MATERIALS AND METHODS: Cyclists were recruited to complete a survey through Facebook® advertisements and outreach to sporting clubs. Swimmers and runners were recruited as a comparison group. Cyclists were categorized into low and high intensity cyclists. Participants were queried using validated questionnaires, including SHIM (Sexual Health Inventory for Men), I-PSS (International Prostate Symptom Score) and NIH-CPSI (National Institutes of Health Chronic Prostatitis Symptom Index), in addition to questions about urinary tract infections, urethral stricture, genital numbness and saddle sores. RESULTS: Of 5,488 complete survey responses 3,932 (72%) were included in our analysis. On multivariate analysis swimmers/runners had a lower mean SHIM score than low and high intensity cyclists (19.5 vs 19.9 and 20.7, p = 0.02 and <0.001, respectively). No significant differences were found in I-PSS or NIH-CPSI scores, or urinary tract infection history. Cyclists had statistically higher odds of urethral stricture compared to swimmers/runners (OR 2.5, p = 0.042). Standing more than 20% of the time while cycling significantly reduced the odds of genital numbness (OR 0.4, p = 0.006). Adjusting the handlebar higher or even with the saddle had lower odds of genital numbness and saddle sores (OR 0.8, p = 0.005 and 0.6, p <0.001, respectively). CONCLUSIONS: Cyclists had no worse sexual or urinary functions than swimmers or runners but cyclists were more prone to urethral stricture. Increased time standing while cycling and a higher handlebar height were associated with lower odds of genital sores and numbness.


Assuntos
Ciclismo/fisiologia , Disfunção Erétil/fisiopatologia , Prostatite/fisiopatologia , Comportamento Sexual/fisiologia , Inquéritos e Questionários , Estreitamento Uretral/fisiopatologia , Micção/fisiologia , Adolescente , Adulto , Idoso , Austrália/epidemiologia , Canadá/epidemiologia , Estudos Transversais , Disfunção Erétil/epidemiologia , Seguimentos , Humanos , Masculino , Pessoa de Meia-Idade , Nova Zelândia/epidemiologia , Projetos Piloto , Prevalência , Prostatite/epidemiologia , Estudos Retrospectivos , Reino Unido/epidemiologia , Estados Unidos/epidemiologia , Estreitamento Uretral/epidemiologia , Adulto Jovem
11.
J Sex Med ; 15(4): 510-518, 2018 04.
Artigo em Inglês | MEDLINE | ID: mdl-29548713

RESUMO

BACKGROUND: Bicycle riding has become an increasingly popular mode of transportation and exercise, especially among women, and previous studies have demonstrated a relationship between cycling and sexual dysfunction, albeit using non-validated questionnaires. AIM: We aimed to explore the relationship between cycling and sexual and urinary dysfunction. METHODS: Cyclists were recruited to complete a survey through Facebook advertisements and outreach to sporting clubs across 5 English-speaking countries. Swimmers and runners were recruited as a comparison group. OUTCOMES: Participants were queried using validated questionnaires, including the Female Sexual Function Index, the American Urological Association Symptom Index, and non-validated questions about history of urinary tract infections (UTIs), genital numbness, and genital saddle sores (all self-reported). RESULTS: 3,118 (53.3%) Women completed the survey, comprising 1,053 (34%) non-cyclists, 1,656 (53%) low-intensity cyclists, and 409 (13%) high-intensity cyclists. After adjusting for age, body mass index, hypertension, diabetes, ischemic heart disease, tobacco use, race, marital status, urinary symptoms, and sexual activity, high-intensity cyclists had lower odds of self-reported sexual dysfunction compared to non-cyclists (adjusted odds ratio [aOR] 0.7, P = .02). There were no statistically significant differences in urinary symptoms across groups. Compared to non-cyclists, both low- and high-intensity cyclists had higher odds of reporting a previous UTI (aOR 1.4, P < .001, and aOR 1.4, P = .009, respectively), genital numbness (odds ratio [OR] 6.5, P < .001, and OR 9.1, P < .001, respectively), and saddle sores (OR 6.3, P < .001, and OR 22.7, P < .001, respectively). CLINICAL TRANSLATION: Women cyclists were more likely to report other genitourinary conditions, including UTIs, genital numbness, and saddle sores. CONCLUSIONS: This is the largest study comparing cyclists to other athletes with respect to sexual and urinary function. The study is limited by its cross-sectional design and sampling methods. We found that women cyclists were no more likely to report sexual dysfunction or urinary symptoms than swimmers or runners. Gaither TW, Awad MA, Murphy GP, et al. Cycling and Female Sexual and Urinary Function: Results From a Large, Multinational, Cross-Sectional Study. J Sex Med 2018;15:510-518.


Assuntos
Ciclismo , Disfunções Sexuais Fisiológicas , Transtornos Urinários , Adolescente , Adulto , Austrália , Canadá , Estudos Transversais , Feminino , Humanos , Pessoa de Meia-Idade , Nova Zelândia , Razão de Chances , Autorrelato , Inquéritos e Questionários , Reino Unido , Estados Unidos , Adulto Jovem
12.
Arch Phys Med Rehabil ; 99(2): 272-280, 2018 02.
Artigo em Inglês | MEDLINE | ID: mdl-28928026

RESUMO

OBJECTIVE: To provide a preliminary evaluation of the effectiveness of an online resource for job seekers with multiple sclerosis (MS). DESIGN: Randomized controlled design. SETTING: Community-dwelling cohort. PARTICIPANTS: Adults (N = 95) with relapsing-remitting or progressive MS were randomly assigned to one of two groups. Forty-five accessed an email delivered, 7 module resource, Work and MS, over a 4 week period. Waitlist control participants (n=50) were offered the opportunity to access Work and MS 4 weeks postenrollment. MAIN OUTCOME MEASURES: Primary outcomes focused on vocational interests (My Vocational Situation Scale) and self-efficacy in job-seeking activities (Job-Procurement Self Efficacy Scale). Secondary outcomes focused on perceived workplace difficulties (Multiple Sclerosis Work Difficulties Questionnaire [MSWDQ]), optimism (Life Orientation Test - Revised), and mood (Patient Health Questionnaire-9). RESULTS: Intention-to-treat analyses revealed pre-post gains: participants who accessed Work and MS reported improved confidence in their career goals (My Vocational Situation Scale g=.55; 95% confidence interval [CI], .14-.96; P=.008) and positively reappraised potential workplace difficulties (MSWDQ g range, .42-.47; P range, .023-.042). The effect on job self-efficacy was not significant, but changed in the expected direction (g=.17; 95% CI, -.23 to .57; P=.409). Completer data revealed larger, significant effect estimates (g range, .52-.64; P range, .009-.035). CONCLUSIONS: Findings provide preliminary support for the utility of a job information resource, Work and MS, to augment existing employment services. The results also suggest the need to test employment-ready interventions in a larger study population. This might include the addition of online peer support to increase intervention compliance.


Assuntos
Esclerose Múltipla/reabilitação , Sistemas On-Line , Reabilitação Vocacional , Retorno ao Trabalho , Adulto , Austrália , Feminino , Humanos , Análise de Intenção de Tratamento , Masculino , Autoeficácia , Inquéritos e Questionários
13.
Inj Prev ; 24(2): 135-141, 2018 04.
Artigo em Inglês | MEDLINE | ID: mdl-28572269

RESUMO

INTRODUCTION: Emergency department visits and hospital admissions resulting from adult bicycle trauma have increased dramatically. Annual medical costs and work losses of these incidents last were estimated for 2005 and quality-of-life losses for 2000. METHODS: We estimated costs associated with adult bicycle injuries in the USA using 1997-2013 non-fatal incidence data from the National Electronic Injury Surveillance System with cost estimates from the Consumer Product Safety Commission's Injury Cost Model, and 1999-2013 fatal incidence data from the National Vital Statistics System costed by similar methods. RESULTS: Approximately 3.8 million non-fatal adult bicycle injuries were reported during the study period and 9839 deaths. In 2010 dollars, estimated adult bicycle injury costs totalled $24.4 billion in 2013. Estimated injury costs per mile bicycled fell from $2.85 in 2001 to $2.35 in 2009. From 1999 to 2013, total estimated costs were $209 billion due to non-fatal bicycle injuries and $28 billion due to fatal injuries. Inflation-free annual costs in the study period increased by 137% for non-fatal injuries and 23% for fatal injuries. The share of non-fatal costs associated with injuries to riders age 45 and older increased by 1.6% (95% CI 1.4% to 1.9%) annually. The proportion of costs due to incidents that occurred on a street or highway steadily increased by 0.8% (95% CI 0.4% to 1.3%) annually. CONCLUSIONS: Inflation-free costs per case associated with non-fatal bicycle injuries are increasing. The growth in costs is especially associated with rising ridership, riders 45 and older, and street/highway crashes.


Assuntos
Acidentes de Trânsito/economia , Acidentes de Trânsito/estatística & dados numéricos , Ciclismo/lesões , Custos de Cuidados de Saúde/estatística & dados numéricos , Ferimentos e Lesões/economia , Ferimentos e Lesões/mortalidade , Adulto , Distribuição por Idade , Ciclismo/economia , Serviço Hospitalar de Emergência/economia , Serviço Hospitalar de Emergência/estatística & dados numéricos , Feminino , Hospitalização/economia , Hospitalização/estatística & dados numéricos , Humanos , Incidência , Masculino , Pessoa de Meia-Idade , Distribuição por Sexo , Estados Unidos/epidemiologia
14.
Mem Cognit ; 46(4): 530-543, 2018 05.
Artigo em Inglês | MEDLINE | ID: mdl-29313292

RESUMO

Categorization research has demonstrated the use of both rules and remembered exemplars in classification, although there is disagreement over whether learners shift from one to the other or use both strategies simultaneously. Theoretical arguments can motivate predictions for both rule use and exemplar use increasing with more practice. We describe a single large experiment (n = 190) that manipulated the number of training items (category size), the number of presentations of each training item, and the similarity between the training and the transfer stimuli in order to discover when rules and exemplars are most likely to be used. Results showed that rules and exemplars both influenced classification and that exemplars were used more often with smaller categories, with more training on items, and when test items were similar to training items. There was no consistent evidence of a shift from rule-based to exemplar-based categorization with more learning. Importantly, we found a number of conditions in which rules and exemplars were both used, even within individual participants. We discuss our results in terms of hybrid models of classification.


Assuntos
Prática Psicológica , Pensamento/fisiologia , Transferência de Experiência/fisiologia , Adulto , Formação de Conceito/fisiologia , Humanos , Adulto Jovem
15.
J Sex Med ; 14(9): 1071-1078, 2017 09.
Artigo em Inglês | MEDLINE | ID: mdl-28859870

RESUMO

BACKGROUND: Erectile dysfunction (ED) after treatment for prostate cancer with radiotherapy (RT) is well known, and pooled estimates of ED after RT will provide more accurate patient education. AIM: To systematically evaluate the natural history of ED in men with previous erectile function after prostate RT and to determine clinical factors associated with ED. METHODS: We performed a review of the PubMed and Medline, Embase, Cochrane Library, and Web of Science databases in April 2016 according to the Preferred Reporting Items for Systematic Review and Meta-analysis (PRISMA) statement. Identified reports included a measurement of ED before and after prostate RT. Two hundred seventy-eight abstracts were screened and 105 publications met the criteria for inclusion. Only men with known erectile function before RT were included in the analysis. OUTCOME: ED after RT of the prostate. RESULTS: In total, 17,057 men underwent brachytherapy (65%), 8,166 men underwent external-beam RT (31%), and 1,046 men underwent both (4%). Seven common instruments were used to measure ED, including 23 different cutoffs for ED. The Sexual Health Inventory for Men (SHIM) was used in 31 studies (30%). Pooled estimates of SHIM-confirmed ED (score <10-17) suggested the prevalence of ED after RT is 34% of men (95% CI = 0.29-0.39) at 1 year and 57% (95% CI = 0.53-0.61) at 5.5 years. Compared with brachytherapy, studies of the two types of radiation increased the proportion of new-onset ED found by 12.3% of studies (95% CI = 2.3-22.4). For every 10% who were lost to follow-up, the proportion of ED reported increased by 2.3% (95% CI = 0.03-4.7). CLINICAL IMPLICATIONS: ED is common regardless of RT modality and increases during each year of follow-up. Using the SHIM, ED is found in approximately 50% patients at 5 years. STRENGTHS AND LIMITATIONS: The strengths of this systematic review include strict inclusion criteria of studies that measured baseline erectile function, no evidence for large effect size bias, and a large number of studies, which allow for modeling techniques. However, all data included in this analysis were observational, which leaves the possibility that residual confounding factors increase the rates of ED. CONCLUSION: Definitions and measurements of ED after RT vary considerably in published series and could account for variability in the prevalence of reported ED. Loss to follow-up in studies could bias the results to overestimate ED. Gaither TW, Awad MA, Osterberg EC, et al. The Natural History of Erectile Dysfunction After Prostatic Radiotherapy: A Systematic Review and Meta-Analysis. J Sex Med 2017;14:1071-1078.


Assuntos
Braquiterapia , Disfunção Erétil , Neoplasias da Próstata , Humanos , Masculino , Braquiterapia/efeitos adversos , Disfunção Erétil/etiologia , Disfunção Erétil/fisiopatologia , Ereção Peniana , Neoplasias da Próstata/radioterapia
16.
Curr Urol Rep ; 18(3): 23, 2017 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-28233229

RESUMO

PURPOSE OF REVIEW: Review the current literature regarding the management of grade IV renal injuries in children. RECENT FINDINGS: Children are at increased risk for renal trauma compared to adults due to differences in anatomy. Newer grading systems have been proposed and are reviewed. Observation of most grade IV renal injuries is safe. Operative intervention is necessary for the unstable patient to control life-threatening bleeding with either angioembolization or open exploration. Symptomatic urinomas may require percutaneous drainage and/or endoscopic stent placement. Ureteropelvic junction (UPJ) disruption, seen more often in children, requires immediate surgical repair. Grade IV renal injuries in children are increasingly managed in a conservative manner.


Assuntos
Rim/lesões , Criança , Drenagem , Embolização Terapêutica , Endoscopia , Hemorragia/terapia , Humanos
17.
J Med Internet Res ; 19(8): e254, 2017 08 22.
Artigo em Inglês | MEDLINE | ID: mdl-28830852

RESUMO

BACKGROUND: Web-based physician ratings systems are a popular tool to help patients evaluate physicians. Websites help patients find information regarding physician licensure, office hours, and disciplinary records along with ratings and reviews. Whether higher patient ratings are associated with higher quality of care is unclear. OBJECTIVE: The aim of this study was to characterize the impact of physician probation on consumer ratings by comparing website ratings between doctors on probation against matched controls. METHODS: A retrospective review of data from the Medical Board of California for physicians placed on probation from December 1989 to September 2015 was performed. Violations were categorized into nine types. Nonprobation controls were matched by zip code and specialty with probation cases in a 2:1 ratio using the California Department of Consumer Affairs website. Web-based reviews were recorded from vitals.com, healthgrades.com, and ratemds.com (ratings range from 1-5). RESULTS: A total of 410 physicians were placed on probation for 866 violations. The mean (standard deviation [SD]) number of ratings per doctor was 5.2 (7.8) for cases and 4 (6.3) for controls (P=.003). The mean rating for physicians on probation was 3.7 (1.6) compared with 4.0 (1.0) for controls when all three rating websites were pooled (P<.001). Violations for medical documentation, incompetence, prescription negligence, and fraud were found to have statistically significant lower rating scores. Conversely, scores for professionalism, drugs or alcohol, crime, sexual misconduct, and personal illness were similar between cases and controls. In a univariate analysis, probation was found to be associated with lower rating, odds ratio=1.5 (95% CI 1.0-2.2). This association was not significant in a multivariate model when we included age and gender. CONCLUSIONS: Web-based physician ratings were lower for doctors on probation indicating that patients may perceive a difference. Despite these statistical findings, the absolute difference was quite small. Physician rating websites have utility but are imperfect proxies for competence. Further research on physician Web-based ratings is warranted to understand what they measure and how they are associated with quality.


Assuntos
Satisfação do Paciente , Médicos , Qualidade da Assistência à Saúde/normas , Adulto , California , Feminino , Humanos , Internet , Masculino , Estudos Retrospectivos
18.
Can J Urol ; 22(5): 8006-8, 2015 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-26432974

RESUMO

A 46-year-old male with a history of hypertension presented with symptoms of persistent abdominal fullness and a non-pulsatile abdominal mass. Subsequent computed tomographic angiography studies revealed the presence multiple large renal aneurysms from the segmental branches of the renal artery and an enlarged hydronephrotic kidney with minimal parenchyma. The renal deterioration appeared to be as a result of an obstruction caused by the large intra-renal aneurysms at the level of the renal calyces. Since the right kidney had no function, an open radical nephrectomy was subsequently performed without complications at 3 months follow up.


Assuntos
Aneurisma/complicações , Aneurisma/cirurgia , Hidronefrose/etiologia , Nefrectomia/métodos , Artéria Renal , Obstrução Ureteral/etiologia , Humanos , Hidronefrose/cirurgia , Masculino , Pessoa de Meia-Idade , Obstrução Ureteral/cirurgia
19.
Aust Crit Care ; 28(3): 160-7, 2015 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-25012764

RESUMO

BACKGROUND: Basic Life Support (BLS) is a life-saving and fundamental skill in resuscitation. However, studies have reported limitations in BLS training outcomes for both health professional and lay populations, and noted the resource and time-intensive nature of traditional training approaches. PURPOSE: This exploratory study evaluated the effectiveness of an interactive CD-based BLS training programme that included unsupervised manikin practice compared with a traditional instructor-led BLS training programme involving demonstration and supervised practice. METHODS: A quasi-experimental post-test with follow-up design was used. The sample was comprised of two cohorts: Novice second-year undergraduate Nursing students (n=187) and Practising Nurses (n=107) in their first year of hospital employment. BLS skill outcomes were assessed at one week and again at eight weeks post training. FINDINGS: No statistically significant differences were found between the CD and traditional instructor-led BLS training methods in BLS skills of Novice and Practising Nurses at one week and eight weeks post training. However, there was a decrement in skill between one week and eight weeks post-training across both groups and an overall low level of competence. CONCLUSION: The failure to find a difference between the CD-based BLS programme with unsupervised manikin practice and a resource-intensive traditional instructor-led BLS training programme may indicate equivalence of the programmes or, even study design limitations. It is concerning that competence displayed by trainees from both groups was less than optimal and suggests the need for renewed efforts to develop and evaluate BLS training programmes which can achieve high rates of competence with acceptable skill retention over time.


Assuntos
Reanimação Cardiopulmonar/educação , Educação Continuada em Enfermagem/métodos , Capacitação em Serviço , Cuidados para Prolongar a Vida , Adolescente , Adulto , Competência Clínica , Discos Compactos , Avaliação Educacional , Feminino , Humanos , Masculino , Manequins
20.
Psychol Sci ; 25(9): 1816-21, 2014 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-25015685

RESUMO

The ability to represent knowledge at the category level promotes the transfer of learning. How this ability integrates with basic forms of conditioned learning is unknown but could explain why conditioned fear is overgeneralized after aversive experiences. We examined the impact of stimulus typicality--an important determinant of category-based induction--on fear learning and generalization. Typicality is known to affect the strength of categorical arguments; a premise involving typical exemplars (e.g., sparrow) is believed to apply to other members, whereas a premise about atypical exemplars (e.g., penguin) generalizes more narrowly to similar items. We adopted this framework to human fear conditioning and found that fear conditioned to typical exemplars generalized more readily to atypical members than vice versa, despite equal feature overlap across conditions. These findings have implications for understanding why some fearful events lead to broad overgeneralization of fear whereas others are regarded as isolated episodes.


Assuntos
Condicionamento Clássico , Medo , Resposta Galvânica da Pele , Generalização Psicológica , Adolescente , Adulto , Feminino , Humanos , Masculino , Adulto Jovem
SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA